The liver is the largest gland in the body, located in the upper right quadrant of the abdomen under the diaphragm and within the rib cage. It has four lobes - two major lobes and two minor lobes - and ducts that carry bile from the liver to the gallbladder and join the pancreatic duct. The liver is made up of lobules containing hepatocytes that radiate outward from a central vein and produce and secrete bile. Blood flows to the liver through the hepatic portal vein and supplies the liver with nutrients and oxygen. The liver performs many important metabolic functions like synthesizing and breaking down substances, and excreting waste from the bloodstream into bile.

1. ANATOMY
OF LIVER

2. The Liver
• Largest gland in the body (1.5 Kg)
• Under the diaphragm, within the rib
cage in the upper right quadrant of the
abdomen

3. The Liver
•4 Lobes
Major: left and
right
Minor: caudate and
quadrate
•Ducts
Common hepatic
Cystic
From gallbladder
Common bile -
Choledochus
Joins pancreatic duct at
hepatopancreatic ampulla

4. liver
•Liver lobules – hexagonal structures consisting of
hepatocytes
• Hepatocytes radiate outward from a central vein
•Hepatocytes produce bile
Bile flows through canals called bile canaliculi to a bile
duct
Bile ducts leave the liver via the common hepatic duct
• At each of the six corners of a lobule is a portal
triad
• Liver sinusoids

7. BLOOD SUPPLY

8. Liver

9. Functions of Liver
• Metabolic
Synthesis
Breakdown
Other functions – storage of vitamin
A,D,B12,F…
• Excretion of waste products from bloodstream
into bile
• Vascular – storage of blood

10. Thank you for your
attention