The document discusses the chain rule in calculus, detailing its definition, applications, and examples for differentiating compositions of functions. It elaborates on the relationship between the derivatives of composite functions using both Newtonian and Leibnizian notations. The key theorem established is that if f and g are differentiable, then the derivative of the composition (f ◦ g)'(x) equals f'(g(x))g'(x).