The Prophet Muhammad (PBUH) had six children with his first wife Khadija: Qasim, who died at age two, Zaynab, Ruqayyah, Umm Khulthum, Fatima, and Abdullah, who also died as a child. He had one child, Ibrahim, with his second wife Maria. The document provides details on each of the Prophet's children, such as who they married and had children with. It also notes that the Prophet was affectionate towards his grandchildren.