Leaders in Science and Society - Prof Richard Gibbs
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Prof Richard Gibbs - Director, Baylor College of Medicine Human Genome Sequencing Centre Wofford Cain Professor of Human & Molecular Genetics. http://www.garvan.org.au/news-events/leaders-in-science-and-society
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The Human Genome Project was a large, international collaborative project launched in 1990 with the main goal of determining the complete DNA sequence of human genes. It involved research groups from six countries and sought to map all human genes to further the study of genetic diseases. By 2003, the project had completed mapping over 99% of the human genome, finding that while genomes are over 99.9% identical, small differences of 0.1% can impact traits and disease susceptibility. The project provided tremendous medical implications, including enabling identification of disease genes and advancing fields like gene therapy and pharmacogenomics.
KCA Big Data and Immunotherapeutics Symposium, August 31st, 2018, Sydney
Kids Cancer Alliance warmly invites you to this symposium featuring the latest developments in big data analytics, bioinformatics and, immunotherapeutic targeting.
An all-day symposium on the genomics of childhood cancer and germline predisposition, immune epitope targeting and CAR T cell therapeutics, and, single-cell transcriptomic and proteomic diagnostics in cancer.
For more details please contact Dr Michael Evtushenko MEvtushenko@ccia.unsw.edu.au
Medical Biotechnology presentation.pptx
Medical biotechnology uses living cells and organisms to develop medical products and therapies. It has applications in areas like stem cell research, the Human Genome Project, recombinant DNA technology, gene therapy, vaccine development, insulin production, diagnostics, and genetic engineering. Some key contributions of medical biotechnology include completing the human genome sequence, producing the first genetically engineered human insulin to treat diabetes, and developing vaccines that have saved millions of lives.
Human genome project ()
This document is not about ways to keep cool in Kathmandu. It discusses the Human Genome Project.
human microbiome project new.pptx
The concept of the human microbiome was first suggested by Joshua Lederberg, who coined the term ‘‘microbiome, to signify the ecological community of commensal, symbiotic, and pathogenic microorganisms that literally share our body space’’
Plegable pdf
Scientists have made progress in mapping the cancer genome and identifying genetic markers for lupus. A study identified many new genetic markers for lupus by analyzing over 27,000 people of European, African, and Hispanic descent. Separately, scientists evaluated algorithms used to analyze the cancer genome, finding that subgene algorithms provide a high-resolution view of how mutations in the same gene can lead to different health outcomes depending on location. Genetic mapping provides medical utility by aiding the discovery of drug targets and enabling targeted research in populations with high disease risk.
Evolution of dental informatics as a major research
This document discusses the evolution of dental informatics as a major research tool in oral pathology. It describes how dental informatics incorporates knowledge from various fields like health science, computer science, and information technology. The primary goals are to increase understanding of biological processes and improve patient outcomes. Major areas of research include gene finding, genome assembly, protein structure prediction, and drug design. Applications discussed include using microarrays and genomics/proteomics for early oral cancer detection, identifying genetic factors that influence disease progression, and cataloging proteins in oral fluids. The conclusion states that combining experimental and theoretical approaches from various disciplines like bioinformatics will provide better understanding of oral diseases at the molecular level.
ISCB ECCB BD2K keynote Kibbe 201707
Cancer Moonshot, funding opportunities for cancer informatics research, BD2K, ISMB, ISCB, ECCB, Prague 2017
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TJU_Newsletter 2008_summer Li photo
The document provides updates from various departments at the Kimmel Cancer Center. It announces new treatments for prostate cancer including high intensity focused ultrasound. It highlights advances in areas like radiation oncology, integrative medicine, and stem cell research. It recognizes support from donors and announces new rankings for cancer care.
March 2, 2016 newsletter
The document discusses the history and progress of medicine and genomics over the past century. It describes how the human genome was sequenced between 2000-2003 and how this sparked the rise of omics technologies and new databases. It also discusses how microarray testing in 2012 revealed two subtypes of diffuse large B cell lymphoma that respond differently to treatments, representing an early achievement of precision medicine. The document advocates that clinical lab scientists help make precision diagnostic tests more widely accessible and efficient to improve health outcomes.
iOncologi_Pitch Deck_2024 slide show for hostinger
iOncologi is developing novel cancer immunotherapies including stem cell therapies and mRNA-nanoparticle vaccines. Their stem cell therapy has shown ability to overcome resistance to immune checkpoint inhibitors in preclinical studies and received FDA approval for clinical trials in glioblastoma patients. Their mRNA-NP vaccine platform is in early phase clinical trials for refractory solid cancers. iOncologi seeks capital to further clinical evaluation and develop allogeneic 'off-the-shelf' stem cell therapies.
Reg Sci Lecture Dec 2016
The document discusses the intersection of precision medicine, biomarkers, and healthcare policy. It describes how biomarkers and -omics data can be used for precision medicine to improve diagnostic accuracy, deliver targeted therapies, and stratify patient populations. However, clinical validation of biomarkers now requires large datasets and years of studies due to regulatory and payer requirements. This has reduced incentives for diagnostic innovation. The document also discusses challenges around clinical interpretation of complex multi-omic tests, evolving medical training and workflows, and disconnects between patent and reimbursement policies.
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With increasing population, people need to rely on packaged food stuffs. Packaging of food materials requires the preservation of food. There are various methods for the treatment of food to preserve them and irradiation treatment of food is one of them. It is the most common and the most harmless method for the food preservation as it does not alter the necessary micronutrients of food materials. Although irradiated food doesn’t cause any harm to the human health but still the quality assessment of food is required to provide consumers with necessary information about the food. ESR spectroscopy is the most sophisticated way to investigate the quality of the food and the free radicals induced during the processing of the food. ESR spin trapping technique is useful for the detection of highly unstable radicals in the food. The antioxidant capability of liquid food and beverages in mainly performed by spin trapping technique.
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Leaders in Science and Society - Prof Richard Gibbs
- 1. Garvan Institute of Medical Research Leaders in Science & Society Prof Richard Gibbs Director, Baylor College of Medicine Human Genome Sequencing Centre Wofford Cain Professor of Human & Molecular Genetics “Precision Medical Research” Monday 30 May 2016 12PM, AUDITORIUM Host: Prof John Mattick Richard Gibbs was born in Australia and graduated from Melbourne University and the Peter MaCallum Cancer Institute in 1986 in Genetics and Radiation Biology. He moved to the USA to Baylor College of Medicine, where he performed key work on the molecular characterization of human genetic disease and provided an early leadership role for the Human Genome Project. In 1997 he founded the BCM Human Genome Sequencing Center – the HGSC – that was one of five main groups to complete the HGP. The HGSC then completed the genomes of many model species and provided leadership for other international projects, including the Mammalian Gene Collection, the Hapmap Project, the 1000 Genomes Project and the Cancer Genome Atlas. The HGSC has also been a technology leader, including developing the DNA exome capture technologies now used ubiquitously. The HGSC continues to work on large scale comparative genomics and development of genome technologies. Beginning in 2007 the group developed the field of personal human genomics, beginning with personal genome sequences of James Watson and James Lupski and culminating with creation of the first Genetics Diagnostics Laboratory to be based on whole gene sequencing. He now leads the HGSC efforts in large scale clinical translation. Gibbs has served on many NIH Advisory Councils and was elected to the National Academy of Medicine in 2011, named an Honorary Fellow of the Royal College of Pathologists of Australasia in 2011 and recognized as one of the 400 most influential biomedical scientists in the world in 2013 (Eur J. Clin. Invest. 2014). He is currently the Wofford Cain Distinguished Professor of Molecular and Human Genetics and Director of the HGSC.