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The document summarizes key points about the human genome project and its impacts over the past 10 years as well as opportunities for the next 10 years. It discusses how the human genome project revealed the blueprint for building a human in 2001 and enabled greater understanding of gene functions and their medical impacts. It then outlines focus areas for genomic medicine in the coming decade like diagnostics, disease biology insights, cancer genome characterization, and clinical informatics. The role of the human microbiome in health and disease is also summarized along with challenges in bioinformatics like data analysis, integration and tools. Ethical and societal issues related to genomics research and medicine are also highlighted.
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The newly developed molecular techniques of genetics identification, gene-splicing, and artificial procedures represent a jump in our ability to control life itself, a command by culture and faith to be the province of a divine agency (Butte & Belsky, 1987). Thus, it would be complete that gene-splicing could be a phenomenon, the genetic engineering that takes place in nature whenever a gene crosses over on chromosomes, a cistron mutates, or a microorganism. Though reproducing systems for each sort of life are utilized for a long time, they require exclusive controlled common procedures to understand their finishes. What makes biotechnology totally not quite the same as logical transformation of the edification, notwithstanding is that science not just dislodges our comprehension of the plants, it allows the United States to rebuild nature to reproduce life itself regardless of whether it’s man, creature, plant, or germ.
Quality grafting methods have enabled analysis to embed qualities from absolutely random species to change life cycles and improve infection obstruction for a spread of oceanic animal categories. Some of the first encouraging strategies have ventured on the far side unobtrusive rearing and refined methods to utilize the hardware of life itself to fortify generations. Biotechnology assures to play the partner degree logically incredible job inside the extra restraining and control of our regular and our unnatural universes
Farming techniques are created to support local fish species with a ton of productivity, accelerate their advancement cycles, and give protection from the spread of ailments and pathogens. It is, therefore, not stunning that because the biological sciences and biotechnology have enjoyed exceptional success throughout the past thirty years, public awareness and discomfort, notably with gene-splicing, have multiplied.
The moral analysis of biotechnology cuts across two distinct ethical domains: the analysis of risks and advantages, and also the analysis of biotechnology in light-weight of broader cultural, religious, and moral principles. Social advantages can't be a basis for argument if the underlying ethical question issues the validity of corroding human advantages against the welfare of alternative species or natural ecosystems within the initial place (Leidos & Marris, 2001).
To argue that gene-splicing is solely associate degree extension of natural organic process processes doesn't virtuously justify the application. There’s a very important distinction between "natural organic process processes" and "natural gene-splicing. Natural organic process processes don't build a selection, they are doing not deliberate with the intention of achieving.
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Student’s name
Instructor
Course
Date
Biological Psychology
Research in the field of biological psychology aims to establish correlations between biological, physiological, and genetic factors and mental health and behavior (greatpacificmedia, 2009). Considering that the brain is the command center for all behavior, biological psychologists investigate its inner workings to better comprehend human nature. According to proponents of the biological view, human behavior directly results from our biological makeup. It's the only school of psychology that takes a physical, biological stance on investigating mental states and actions. Thus, it may be concluded that the physiological basis for the psychological is absolute. In this discussion, three significant technology advances such as High-throughput screening (HTS) technology, DNA synthesis technology, nanotechnology and biotechnology will be discussed in relation to the history of biological psychology
The term "high-throughput screening" (HTS) technology refers to a way to test a large number of biomolecular or chemical compounds quickly and efficiently for certain qualities. Access to these kinds of technologies is significant for reaping any benefits from building extensive libraries of compounds since they are used to zero down on a specific chemical with the needed qualities. Some examples of these traits are the biochemical or enzymatic activity that is wanted in a potential therapeutic drug or toxicity that would usually be avoided in such an agent. Increased productivity in biological assays is a hallmark of HTS, which has been made possible by developments in miniaturized screening technologies, bioinformatics, robotics, and other technologies (greatpacificmedia, 2009).
The merging of nanotechnology and biotechnology and the progress in both fields have impacted biological psychology. The growth of this field is also affected by what has been learned and how it has been used in RNAi and synthetic biology. Biomolecules are made to do certain things but are not called nanomaterials because they are not made in a lab. The progress in understanding the sequences of nucleotides and amino acids in nucleic acids and proteins is also crucial (Mazziotta, 2000). As time goes on, it becomes clearer that RNAi is linked to the broad control of gene expression by micro-RNAs, which are tiny RNA molecules produced endogenously (miRNA). There is a lot of interest in how miRNAs control gene expression during and after development. Every day, latest information comes out about this. Endogenous miRNAs reduce the expression of proteins that interact inside the cell by making the mRNA less stable or stopping it from being translated into protein (Bassett & Bullmore, 2009).
To instruct cells to produce a particular protein, DNA synthesis technology allows for the de novo production of genetic sequences. It is not brand new, but technological advances have made it p.
Impact of the human genome project on medical advancement in India.
Impact of the human genome project on medical advancement in India.University of Petroleum and Energy studies
This document discusses the impact of the Human Genome Project on medical advancement in India. It provides background on the human genome and the goals and processes of the Human Genome Project. Completing the human genome sequence provides benefits like enabling the diagnosis and treatment of genetic diseases in India. However, challenges remain like determining gene functions and understanding complex genetic traits. Overall, the document argues that further utilizing genome sequencing can help India better understand and manage its burden of genetic diseases.Gellibolian 2010 Audio Visual2
The document discusses various technologies used at the House Ear Institute including genomics, proteomics, and imaging. It describes how researchers are using these tools to study diseases like neurofibromatosis type 2 (NF2) at the molecular level in order to develop personalized treatments and therapies. Maintaining high quality biospecimens is important for enabling various types of research.
Brn jm anto-11062014
This document summarizes a presentation on applying systems biology approaches to epidemiology and personalized medicine. It discusses how epidemiology has evolved from studying single risk factors to investigating complex interactions between genes, environments and diseases. Systems approaches integrate multiple levels of data to gain insights into disease mechanisms. Large consortia now apply these methods to conditions like asthma and COPD to understand their complexity. Epidemiology contributes a population perspective and helps develop evidence-based systems medicine frameworks.
Methods to enhance the validity of precision guidelines emerging from big data
A talk on the use (and misuse) of using observational big data streams for medical guideline development.
Human Genome Project
The document provides an overview of the Human Genome Project (HGP). The HGP was an international scientific research project that aimed to determine the sequence of nucleotide base pairs that make up human DNA and identify and map all human genes. The project began in 1990 and was completed in 2003, two years ahead of schedule. Key outcomes included identifying over 1800 disease genes, developing over 1000 genetic tests, and determining that the human genetic origin is from Africa. The project helped lay the groundwork for advances in personalized medicine.
Interdisciplinarity and complexity as opportunities for research innovation i...
Interdisciplinarity and complexity as opportunities for research innovation i...Health and Biomedical Informatics Centre @ The University of Melbourne
In June this year, Prof Martin-Sanchez traveled to Heidelberg, Germany to represent HBIR and University of Melbourne participating in a three day scientific symposium "Biomedical Informatics: Confluence of Multiple Disciplines”.
These are the slides from the presentation he gave to the symposium.A Global Assessment Of Stem Cell Engineering
This document summarizes a global assessment of stem cell engineering (SCE) conducted from 2011-2012 by a panel of six experts. The study was sponsored by several US government science agencies and aimed to evaluate the status and trends in SCE worldwide, including both basic research and clinical/commercial translation. The panel found that SCE activities have increased significantly around the world in recent years. They concluded that greater involvement of engineers is needed to advance the field and generate new economic opportunities. To achieve this will require increased investment in engineering research and commercialization related to stem cells. The study involved site visits to institutions in Asia and Europe as well as workshops to assess SCE efforts and identify opportunities for collaboration between countries.
The biotechnology revolution - Background information
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ContentMine at EuropePMC AGM
This document summarizes content mining of biomedical literature and policy developments surrounding it. It defines content mining as using automated methods to exploit knowledge in biomedical literature. Examples discussed include building phylogenetic trees, extracting chemical reactions, and improving genome annotation. Legal considerations around copyright, databases, and contracts are also addressed. Developments in relevant UK and EU laws from 2011-2015 aimed to support these transformative technologies and help researchers.
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application_of_bioinformatics_in_various_fields.ppt
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My presentation2
- 1. Presentation on The Human Genome at Ten (BT-415) PRIYANKA SARKAR Roll: 40911 No: 0525241 Regn. No: 24401850 of 2009-10.
- 2. A genome is an organism’s complete set of DNA, including all of its genes. Each genome contains all of the information needed to build and maintain that organism. In February 2001, the IHGSC and Celera Genomics each reported draft sequences providing a first overall view of the human genome (Nature, 409 (6822): 860-921, 2001and Science 291(5507): 1304-1351, 2001). The work of the Human Genome Project has allowed researchers to understand the blueprint for building a person. As researchers learn more about the functions of genes and proteins, this knowledge will have a major impact in the fields of medicine, biotechnology, and the life sciences. After revealing the Human Genome Sequence in 2001, Systematic Study of genome begins which include Identification of genes , protein architecture, genome composition, Transposable elements, etc. The Human Genome Project marked a new approach in biomedical research, in which the scientific community came together to systematically characterize a large domain of important biological knowledge in the post genomic era.
- 3. NATURE VOL 470: 10 FEBRUARY 2011
- 4. Human genome at future ten 1. Genomic Medicine (From base pair to bedside) Opportunities for genomic medicine will come from acquiring foundational knowledge of genome function, insights into disease biology and powerful genomic tools. The following imperatives will capitalize on these opportunities in the coming decade. Making genomics-based diagnostics routine. Defining the genetic components of disease. Comprehensive characterization of cancer genomes. Practical systems for clinical genomic informatics. (NATURE VOL 470: 10 FEBRUARY 2011) The role of the human microbiome in health and disease: Many diseases are influenced by the microbial communities that inhabit our bodies (the microbiome). Recent initiatives are using new sequencing technologies to catalogue the resident microflora at distinct body sites, and studying correlations between specific diseases and the composition of the microbiome.
- 5. Human genome at future ten 2. Bioinformatics and Computational Biology: Advancement in the Bioinformatics can meet the following challenges in future: Data analysis. Data integration. Visualization Computational tools and infrastructure. Genomics and society: Psychosocial and ethical issues in genomics research. Psychosocial and ethical issues in genomic medicine. Legal and public policy issues. Broader societal issues. NATURE VOL 470: 10 FEBRUARY 2011
- 6. The Future Is Bright