Late blight of potato is caused by the fungus Phytophthora infestans. It initially infects the lower leaves and can attack the plant at any time after foliage develops. The disease leads to water soaked spots on leaves that turn purple-brown and black, and white growth develops on the underside of leaves. It also causes purplish brown spots on tubers. Cool, humid conditions favor the spread of the disease. Control measures include using resistant varieties, avoiding bruising of tubers, and regularly spraying fungicides like mancozeb every 10-15 days during crop growth.