This document contains radiographs and photomicrographs showing various bone diseases and conditions. It includes images of osteogenesis imperfecta showing opaque dentin and blue sclera. Images also show osteopetrosis with sclerotic bone replacing marrow spaces. Cleidocranial dysplasia is depicted with unerupted teeth. Other images show focal osteoporotic marrow defects, idiopathic osteosclerosis, condensing osteitis, Paget's disease with abnormal bone formation, giant cell tumor, and massive osteolysis with extensive bone loss.

1. OSTEOGENESIS IMPERFECTA. A. OPALESCENT DENTIN IN A PATIENT WITH
OSTEOGENESIS IMPERFECTA. B. BITE-WING RADIOGRAPH OF THE SAME PATIE NT
SHOWING SHELL TEETH WITH THIN DENTIN AND ENAMEL OF NORMAL THICKNESS.

2. OSTEOGENESIS IMPERFECTA. BLUE SCLERA IN A
PATIENT WITH OSTEOGENESIS IMPERFECTA

4. OSTEOPETROSIS. THIS 24 -YEAR-OLD WHITE MAN HAS THE
INFANTILE FORM OF OSTEOPETROSIS. HE HAS SUFFERED FROM
MANDIBULAR OSTEOMYELITIS. AND MULT IPLE DRAINING FISTULAE
ARE PRESENT ON HIS FACE.

8. OSTEOPETROSIS. LOW-POWER PHOTOMICROGRAPH SHOWING SCLEROTIC BONE
THAT IS REPLACING THE NORMAL CANCELLOUS BONE. THE INSET SHOWS A
NODULAR PATTERN OF THE DENSE BONE OBLITERATING THE MARROW SPACES.

9. CLEIDOCRANIAL DYSPLASIA. THE PATIENT CAN
ALMOST APPROXIMATE HER SHOULDERS IN FRONT
OF HER CHEST.

10. CLEIDOCRANIAL DYSPLASIA. PANORAMIC RADIOGRAPH
SHOWING MULTIPLE UNERUPTED TEETH.

11. FOCAL OSTEOPOROTIC MARROW DEFECT. THE PERIAPICAL
FILM SHOWS A RADIOLUCENT AREA CONTAINING FINE
TRABECULATLONS.

12. FOCAL OSTEOPOROTIC MARROW DEFECT. PHOTORNICROGRAPH
SHOWING NORMAL HEMATOPOIETIC BONE MARROW.

13. IDIOPATHIC OSTEOSCLEROSIS. A. AN ASYMPTOMATIC AREA OF BANE
SCLEROSIS IS SEEN BETWEEN AND APICAL TO THE ROOTS OF THE FIRST AND
SECOND MANDIBULAR MOLARS. B, NO APPRECIABLE CHANGE CAN BE SEEN
ON THIS RADIOGRAPH TAKEN 10 YEARS LATER.

14. CONDENSING OSTEITIS. INCREASED AREAS OF RADIODENSITY
SURROUNDING THE APICES OF THE NONVITAL MANDIBULAR FIRST
MOLAR.

15. BONE SCAR. RESIDUAL AREA OF INCREASED
RADIODENSITY
IN THE AREA OF EXTRACTION OF THE MANDIBULAR FIRST
MOLAR.

19. PAGET'S DISEASE. LATERAL SKULL FILM SHOWS MARKED ENLARGEMENT OF THE
CRANIUM WITH NEW BONE FORMATION ABOVE THE OUTER TABLE OF THE SKULL AN
A PATCHY, DENSE, "COTTON WOOL“ APPEARANCE.

20. PAGET'S DISEASE. PERIAPICAL FILM SHOWING THE
"COTTON WOOL" APPEARANCE OF THE BONE.

22. PAGET'S DISEASE. PROMINENT OSTEOBLASTIC AND
OSTEOCLASTIC ACTIVITY SURROUND THE BONE
TRABECULAE. NOTE THE RESTING AND REVERSAL LINES.

23. GIANT CELL TUMOR. THIS PHOTOMICROGRAPH SHOWS
LARGE GIANT CELLS THAT ARE DISTRIBUTED IN A CELLULAR MESENCHYMAL
TISSUE. THIS SPECIMEN WAS FROMAN AGGRESSIVE LESION THAT HAD
DESTROYED MOST OF THE MAXILLA.

24. MASSIVE OSTEOLYSIS. PERIAPICAL RADIOGRAPH SHOWING AN ILL-DEFINED
RADIOLUCENCY ASSOCIATED WITH VITAL MANDIBULAR TEETH.
NOTE THE LOSS OF LAMINA DURA.

25. MASSIVE OSTEOLYSIS. PANORAMIC RADIOGRAPH OF THE SAME
PATIENT, SHOWING EXTENSIVE BONE LOSS AND A PATHOLOGIC
FRACTURE OF THE LEFT MANDIBLE. THIS DESTRUCTION OCCURRED
OVER AN 8-MONTH PERIOD.

26. MASSIVE OSTEOLYSIS. BIOPSY SPECIMEN FROM THE SAME PATIENT.
THE LOOSE. HIGHLY VASCULAR CONNECTIVE TISSUE SHOWS A
DIFFUSE CHRONIC INFLAMMATORY CELL INFILTRATE.