This document discusses jaw deformities including their definition, history, classification, treatment considerations, and complications. It provides details on congenital and acquired causes such as trauma during birth, wisdom tooth removal, and infections. Specific conditions that can cause jaw deformities like Treacher Collins syndrome and Pierre Robin sequence are explained. The treatment of early jaw deformity cases and development of procedures like Le Fort osteotomies are summarized.
A cyst is an epithelium-lined sac containing fluid or semisolid material. In the formation of a cyst, the epithelial cells first proliferate and later undergo degeneration and liquefaction. The liquefied material exerts equal pressure on the walls of the cyst from within. Cysts grow by expansion and thus displace the adjacent teeth by pressure. May can produce expansion of the cortical bone. On a radiograph, the radiolucency of a cyst is usually bordered by a radiopaque periphery of dense sclerotic bone. The radiolucency may be unilocular or multilocular. Odontogenic cysts are those which arise from the epithelium associated with the development of teeth. The source of epithelium is from the enamel organ, the reduced enamel epithelium, the cell rests of Malassez or the remnants of the dental lamina.
A cyst is an epithelium-lined sac containing fluid or semisolid material. In the formation of a cyst, the epithelial cells first proliferate and later undergo degeneration and liquefaction. The liquefied material exerts equal pressure on the walls of the cyst from within. Cysts grow by expansion and thus displace the adjacent teeth by pressure. May can produce expansion of the cortical bone. On a radiograph, the radiolucency of a cyst is usually bordered by a radiopaque periphery of dense sclerotic bone. The radiolucency may be unilocular or multilocular. Odontogenic cysts are those which arise from the epithelium associated with the development of teeth. The source of epithelium is from the enamel organ, the reduced enamel epithelium, the cell rests of Malassez or the remnants of the dental lamina.
Cleft Lip and Palate - Presentation.
Cleft Lip and Palate is the 2nd most common Congenital Anomaly after Clubfoot. This presentation goes in depth about the Presentation, eitiology, Genetics, Medical management, Nasoalveolar Moulding, Surgical management of Cleft Lip & Palate
DEVELOPMENTAL DISTURBANCES OF JAWS & DENTAL ARCH / oral surgery courses Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
Cleft Lip and Palate - Presentation.
Cleft Lip and Palate is the 2nd most common Congenital Anomaly after Clubfoot. This presentation goes in depth about the Presentation, eitiology, Genetics, Medical management, Nasoalveolar Moulding, Surgical management of Cleft Lip & Palate
DEVELOPMENTAL DISTURBANCES OF JAWS & DENTAL ARCH / oral surgery courses Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
Description :
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
diagnosing disc position- does it matter in orthodontics /certified fixed o...Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy provides dental crown & Bridge,rotary endodontics,fixed orthodontics,
Dental implants courses.for details pls visit www.indiandentalacademy.com ,or call
00919248678078
Clinical Digital Photography in OrthodonticsMustafa Haddad
Clinical Digital Photography in Orthodontics
Clinical Digital Photography in Orthodontics
Clinical Digital Photography in Orthodontics
Clinical Digital Photography in Orthodontics
Clinical Digital Photography in Orthodontics
Clinical Digital Photography in Orthodontics
Clinical Digital Photography in Orthodontics
Clinical Digital Photography in Orthodontics
Clinical Digital Photography in Orthodontics
Clinical Digital Photography in Orthodontics
Clinical Digital Photography in Orthodontics
Clinical Digital Photography in Orthodontics
Presented By Dr. MUSTAFA HADDAD
MSD , MCU 1st Year , 1st Semester
Presented By Dr. MUSTAFA HADDAD
MSD , MCU 1st Year , 1st Semester
Presented By Dr. MUSTAFA HADDAD
MSD , MCU 1st Year , 1st Semester
Presented By Dr. MUSTAFA HADDAD
MSD , MCU 1st Year , 1st Semester
Sinus Lift and Immediate Implant PlacementDental Evo
Sinus Lift and Immediate Implant Placement, using LAS kit and TS3 implants.
Presentation by Dr Nicola Baldini DDS
http://www.dentalevo.it/dentistry-materials/sinus-lift-big-buccal-window/
http://www.dentalevo.it/dentistry-materials/sinus-lift-small-buccal-window/
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
Primary etiologic sites:
1- Neuromuscular system:
The muscle group that serve most frequently as primary etiologic sites are:
== muscles of mastication
== muscles of facial expression
== tongue
The neuromuscular system plays its primary role in the etiology of dentofacial deformity by the effect of abnormal contraction of bony skeleton and the dentition. Both bones and teeth are affected by the many functional activities of orofacial region
2- Bone:
Since the bone pf maxilla and mandible serve as bases of dental arches, changes in dental arches growth may alter the occlusal and functional relationship.
3- Teeth;
The teeth may be primary sites in the etiology of dentofacial deformity in many ways
Gross variation in size and shape are encountered frequently and always are of concern
Decrease or increase in the regular number of teeth will give rise malocclusion
Etiologic factors:
A- Extrinsic factors:
1- Evolution:
With evolution, the jaws become smaller, reduction in number and size of teeth and diminution of jaw projections together with increased in vertical height of the face and there is a retrognathic tendency in mans as he ascends the evolutionary scale
2- Heredity:
Transmission of dentofacial characteristics through generations by genes. Most authors between 1900-- 1920 did not completely determine the role of inheritance in determination of the form, size and proportion of dentofacial skeleton, but they stress their work upon the effect of the environmental factors, and at this time they were hardly belief that the effect of local lack of function is more important.
Bennet statement: the size, form and density of bones such as maxilla and mandible varies according to the extent to which these structure are used during period of growth – (function stimulate growth)
Walk Joff statement: the form and degree of development of maxilla and mandible depends upon the magnitude of functional stimuli of muscles acting upon these structures.
Baker: his study was performed on animals by unilateral amputation of muscles of mastication, he found lack of growth on the affected side.
Brash: studied the facial form and the dental development in twins on genetic bases, he also emphasized the genetic facial pattern of some royal families in Europe where they had been inter-marriage, his studies gave the best evidence to support the role of inheritance
Axel Lundstorm:1925 showed that, the form and size of dental bases and the teeth are genetically determined, when the size of the teeth and their basal arches are not correlated, problems of crowding or spacing will be arising.
Broadbent and Hofrath 1931: developed standardized cephalometric x-ray technique which permit serial longitudinal studies of facial growth, by this studies the concept of inheritance growth pattern arises
There are three types of transmission of malocclusion from the standpoint of genetics:
a- Repetitive: the recurrence of single dentofacial deviation within the immediate famil
The presentation expalin major anomilies terminology and it's classification according to the site as: jaws, palate, lips gingivae, tongue, salivary gland, line of fusion and teeth
SYN= TOGETHER ,DROMOS= A RUNNING
“The aggregate of signs & symptoms associated with any morbid process & constituting together the picture of the disease and related to each other anatomically, biochemically or physiologically”
A group of deformations and malformation sequences, etc. that occur together due to some identifiable underlying cause.
Syndromes can be caused by chromosomes anomalies, single genes mutations, teratogens, or other causes.
management of orofacial clefts.pptxmanagement of orofacial clefts.pptxmanagement of orofacial clefts.pptxmanagement of orofacial clefts.pptxmanagement of orofacial clefts.pptx
Embryology, Anatomy, diagnosis, Management of individuals with clefts of the lip and/or palate, Management in the neonatal period, Management during childhood, Cleft management in adolescence and early adulthood, Importance of dental care in overall management,
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
3. A true resultant deformity of the jaw
bone/bones due to congenital anomalies
or acquired during the growth and
development of an individual (trauma,
habbits, familial, pathology or post cancer
surgery).
5. •
The first known correction of jaw deformity was carried out without
anaesthesia in the mid 19th century by an American, General
Surgeon Simon Hullihen.
• He was referred a patient with gross facial deformities as the result of
scarring from burns early in childhood, with a history of multiple
previous operations.
• He undertook initially an osteotomy of the mandible, repositioning
the anterior segment to correct an anterior open bite and
subsequently he carried out soft tissue surgery to improve the overall
appearance and functionality of the soft tissues of the lips, chin and
neck to return them to their normal position thus achieving lip closure
and a relatively normal facial profile. That was in 1848 .
6. • Maxillary surgery for tumour removal had been carried out in the
19th century by von Langenbeck in Germany and by Cheever in the
US.
• It was not until the 1920’s that midface surgery as previously described
in the 19th century was specifically used to correct maxillary
deformity where there was severe maxillary retrusion often in
association with cleft palate problems.
• Martin Wassmund and Georg Axhausen were the first in Germany
to develop the procedure for midface deformity .
• Le Fort I osteotomy became widely accepted for the correction of low
midface deformity often in conjunction with mandibular surgery.
20. A congenital condition of facial abnormalities in humansin which a
chain of certain developmental malformations, one entailing the next.
The 3 main features are cleft palate, micrognathia , glossoptosis
Pierre Robin sequence may be caused by genetic anomalies at
chromosomes 2, 11, or 17.
21. • Also known as Oculo-Auriculo-Vertebral (OAV) syndrome
• Characterized by incomplete development of the ear, nose, soft
palate, lip, and mandible.
26. • Crouzon in 1912
• Crouzon syndrome (craniofacial dysostosis)is a genetic disorder
known as a branchial arch syndrome.
• This syndrome affects the first branchial (or pharyngeal) arch, which
is the precursor of the maxilla and mandible.
27. • Classified by apert in 1906
• Apert syndrome is a form of acrocephalosyndactyly, a congenital
disorder characterized by malformations of the skull, face, hands and
feet.
• It is classified as a branchial arch syndrome, affecting the
first branchial (or pharyngeal) arch, the precursor of
the maxilla and mandible.
28. •
•
•
•
•
Hypoplasia of maxilla
Failure of eruption of permanent teeth.
Frontal Bossing (bulging) of the forehead.
Open skull sutures, large fontanelles.
Hypertelorism.
Decribed in 1900 by Treacher-Collins.Termed mandibulofacialdysosteosis by franceschetti & klein 1944 & 1949.a rare autosomal dominant congenital disorder characterized by craniofacial deformities, such as absent cheekbones.
Pierre Robin syndrome (abbreviated to PRS, and also known as Pierre Robin malformation, Pierre Robin sequence,Pierre Robin anomaly or Pierre Robin anomalad), is a congenital condition of facial abnormalities in humans. PRS is a sequence, i.e. a chain of certain developmental malformations, one entailing the next. The 3 main features are cleft palate,micrognathia (a small jaw) and glossoptosis (airway obstruction caused by backwards displacement of the tongue base). A genetic cause to PRS was recently identified. Pierre Robin sequence may be caused by genetic anomalies at chromosomes 2, 11, or 17.
Goldenhar syndrome (also known as Oculo-Auriculo-Vertebral (OAV) syndrome) is a rare congenital defectcharacterized by incomplete development of the ear, nose, soft palate, lip, and mandible. It is associated with anomalous development of the first branchial arch and second branchial arch.[1] Common clinical manifestations include limbaldermoids, preauricular skin tags, and strabismus.[2]Chief markers of Goldenhar syndrome are incomplete development of the ear, nose, soft palate, lip, and mandible on usually one side of the body. Additionally, some patients will have growing issues with internal organs, especially heart, kidneys, and lungs.
Crouzon syndrome is a genetic disorder known as a branchial arch syndrome. This syndrome affects the first branchial (or pharyngeal) arch, which is the precursor of the maxilla and mandible. Since the branchial arches are important developmental features in a growing embryo, disturbances in their development create lasting and widespread effects.
Crouzon syndrome is a genetic disorder known as a branchial arch syndrome. Specifically, this syndrome affects the first branchial (or pharyngeal) arch, which is the precursor of the maxilla and mandible. Since the branchial arches are important developmental features in a growing embryo, disturbances in their development create lasting and widespread effects.
Fibrous dysplasia (FD) is a slowly progressive condition characterized by replacement of normal bone with an amalgamate of cellular fibrous tissue and irregular bony trabeculae.Genetically, there is a post-zygotic mutation of the gene GNAS1, on the long (q) arm of chromosome 20 at position 13.3, which is involved in G-protein signalling.[4] This mutation, often a mosaicism, prevents downregulation of cAMP signalling.Polyostotic fibrous dysplasia is usually caused by mosaicism for a mutation in a gene called GNAS1 (Guanine Nucleotide binding protein, Alpha Stimulating activity polypeptide 1).