This document summarizes the differing early understandings and uses of the term "bioethics" put forth by Van Rensselaer Potter and scholars at Georgetown University. While Potter conceived of bioethics as addressing broad environmental and public health issues, Georgetown focused it more narrowly on medical ethics issues. Though initially at odds, the document argues Hellegers at Georgetown also envisioned a global scope for bioethics. It analyzes how Georgetown's definition became dominant due to various intellectual, practical, and institutional factors while Potter's view remained marginalized, despite his role in coining the term.
Inter specific hybridization to introduce useful genetic variability for pig...Vipin Pandey
Pulses occupy an important place in Indian agriculture. Within this protein-rich group of crops, red gram or pigeonpea occupies an important place among rainfed resource poor farmers because it provides quality food, fuel wood, broom and fodder.
Hybrids are plants that result from controlled cross-breeding of two different but specific varieties or breeding lines of the same species of plant. Wild species are important sources of resistance to biotic and abiotic stresses as they have evolved to survive droughts, floods, extremes of temperature (heat/ cold) and have the capability to with stand damage by insect pests and diseases. Ten alleles reported unique to inter-specific derivatives of Cajanus cajan × C. scarabaeoides. The presence of alleles unique to specific population or group indicates an inimitable genetic variability at certain loci. This information is valuable to categorise interspecific hybrids with exclusive genetic variability, whose selection can increase the allele richness of breeding population (Saxena, 2015).
High levels of resistance is available in wild Cajanus species, these are not being utilised adequately in pigeonpea breeding programs. The major limitation is due to the linkage drag and different incompatibility barriers between cultivated and wild species. Under such situations, pre-breeding provides a unique opportunity to expand primary gene pool by exploiting genetic variability present in wild species and cultivated germplasm and will ensure continuous supply of new and useful genetic variability into the breeding pipelines to develop new cultivars having high levels of resistance and broad genetic base (Sharma et al., 2013). The major limitation in successfully using Cajanus platycarpus for the improvement of cultivated pigeonpeais embryo abortion in the BC1 generation from the cross C. Platycarpus × C. cajan. This Cajanus platycarpus, although placed in the tertiary gene pool of pigeonpea, is now amenable to gene transfer with the development of suitable embryo rescue techniques (Mallikarjuna et al., 2011).
Genomics platform for agriculture-CAT lectureSenthil Natesan
The popular lecture for the undergraduate students of agriculture to know about the application of biotechnology in agriculture science graduates. Some of the major break through inventions how it impact on agriculture research and development
Inter specific hybridization to introduce useful genetic variability for pig...Vipin Pandey
Pulses occupy an important place in Indian agriculture. Within this protein-rich group of crops, red gram or pigeonpea occupies an important place among rainfed resource poor farmers because it provides quality food, fuel wood, broom and fodder.
Hybrids are plants that result from controlled cross-breeding of two different but specific varieties or breeding lines of the same species of plant. Wild species are important sources of resistance to biotic and abiotic stresses as they have evolved to survive droughts, floods, extremes of temperature (heat/ cold) and have the capability to with stand damage by insect pests and diseases. Ten alleles reported unique to inter-specific derivatives of Cajanus cajan × C. scarabaeoides. The presence of alleles unique to specific population or group indicates an inimitable genetic variability at certain loci. This information is valuable to categorise interspecific hybrids with exclusive genetic variability, whose selection can increase the allele richness of breeding population (Saxena, 2015).
High levels of resistance is available in wild Cajanus species, these are not being utilised adequately in pigeonpea breeding programs. The major limitation is due to the linkage drag and different incompatibility barriers between cultivated and wild species. Under such situations, pre-breeding provides a unique opportunity to expand primary gene pool by exploiting genetic variability present in wild species and cultivated germplasm and will ensure continuous supply of new and useful genetic variability into the breeding pipelines to develop new cultivars having high levels of resistance and broad genetic base (Sharma et al., 2013). The major limitation in successfully using Cajanus platycarpus for the improvement of cultivated pigeonpeais embryo abortion in the BC1 generation from the cross C. Platycarpus × C. cajan. This Cajanus platycarpus, although placed in the tertiary gene pool of pigeonpea, is now amenable to gene transfer with the development of suitable embryo rescue techniques (Mallikarjuna et al., 2011).
Genomics platform for agriculture-CAT lectureSenthil Natesan
The popular lecture for the undergraduate students of agriculture to know about the application of biotechnology in agriculture science graduates. Some of the major break through inventions how it impact on agriculture research and development
Within the last twenty years, molecular biology has revolutionized conventional breeding techniques in all areas. Biochemical and Molecular techniques have shortened the duration of breeding programs from years to months, weeks, or eliminated the need for them all together. The use of molecular markers in conventional breeding techniques has also improved the accuracy of crosses and allowed breeders to produce strains with combined traits that were impossible before the advent of DNA technology
All living organisms have the ability
to improve themselves through
natural means in order to adapt to
changing environmental conditions.
However, it takes hundreds of years
before any detectable improvement
is obtained. Man then learned how
to domesticate and breed plants
in order to develop crops to his
own liking and needs using various
means including biotechnology.
Biotechnology is defined as
a set of tools that uses living
organisms (or parts of organisms)
to make or modify a product,
improve plants, trees or animals,
or develop microorganisms
for specific uses. Agricultural
biotechnology is the term used in
crop and livestock improvement
through biotechnology tools. This
monograph will focus only on
agricultural crop biotechnology.
Biotechnology encompasses a
number of tools and elements of
conventional breeding techniques,
bioinformatics, microbiology,
molecular genetics, biochemistry,
plant physiology, and molecular
biology.
The biotechnology tools that
are important for agricultural
biotechnology include:
- Conventional plant breeding
- Tissue culture and
micropropagation
- Molecular breeding or marker
assisted selection
- Genetic engineering and GM
crops
- Molecular Diagnostic Tools
Marker Assisted Selection in Crop BreedingPawan Chauhan
Marker Assisted Selection is a value addition to conventional methods of Crop Breeding. It has been gaining importance in plant breeding with new generation of plant breeders and to get accurate and fast desired result from plant breeding.
Molecular Breeding in Plants is an introduction to the fundamental techniques...UNIVERSITI MALAYSIA SABAH
This slide describe the process of molecular breeding in plants which involves the application of molecular markers for Marker Assisted Selection and Marker Assisted Breeding.
Within the last twenty years, molecular biology has revolutionized conventional breeding techniques in all areas. Biochemical and Molecular techniques have shortened the duration of breeding programs from years to months, weeks, or eliminated the need for them all together. The use of molecular markers in conventional breeding techniques has also improved the accuracy of crosses and allowed breeders to produce strains with combined traits that were impossible before the advent of DNA technology
All living organisms have the ability
to improve themselves through
natural means in order to adapt to
changing environmental conditions.
However, it takes hundreds of years
before any detectable improvement
is obtained. Man then learned how
to domesticate and breed plants
in order to develop crops to his
own liking and needs using various
means including biotechnology.
Biotechnology is defined as
a set of tools that uses living
organisms (or parts of organisms)
to make or modify a product,
improve plants, trees or animals,
or develop microorganisms
for specific uses. Agricultural
biotechnology is the term used in
crop and livestock improvement
through biotechnology tools. This
monograph will focus only on
agricultural crop biotechnology.
Biotechnology encompasses a
number of tools and elements of
conventional breeding techniques,
bioinformatics, microbiology,
molecular genetics, biochemistry,
plant physiology, and molecular
biology.
The biotechnology tools that
are important for agricultural
biotechnology include:
- Conventional plant breeding
- Tissue culture and
micropropagation
- Molecular breeding or marker
assisted selection
- Genetic engineering and GM
crops
- Molecular Diagnostic Tools
Marker Assisted Selection in Crop BreedingPawan Chauhan
Marker Assisted Selection is a value addition to conventional methods of Crop Breeding. It has been gaining importance in plant breeding with new generation of plant breeders and to get accurate and fast desired result from plant breeding.
Molecular Breeding in Plants is an introduction to the fundamental techniques...UNIVERSITI MALAYSIA SABAH
This slide describe the process of molecular breeding in plants which involves the application of molecular markers for Marker Assisted Selection and Marker Assisted Breeding.
WHAT IS BIOETHICS?
Potter's definition .
The problems, which are significant to all mankind.
The problems connected with the appearance of new medical knowledge and technologies.
The central value of bioethics is life in general.
The Doctor and the Good Life - Introduction to Bioethics and Natural LawAmiel Villanueva
Second version of my lecture on medical ethics / bioethics to the Learning Unit II class of the UP College of Medicine as part of IDC 201: History of Medicine. This was presented last May 9, 2018.
Slide design by SlidesCarnival (slidescarnival.com)
By Paul J. HoehnerThroughout the land, arising from the throngTawnaDelatorrejs
By Paul J. Hoehner
Throughout the land, arising from the throngs of converts to bioethics awareness, there can be heard a mantra, “...beneficence…autonomy…justice…” It is this ritual incantation in the face of biomedical dilemmas that beckons our inquiry (Clouser & Gert, 1990, p. 219).
Ethics as a theological discipline is the auxiliary science in which an answer is sought in the Word of God to the questions of the goodness of human conduct. As a special elucidation of the doctrine of sanctification it is reflection on how far the Word of God proclaimed and accepted in Christian preaching effects a definite claiming of man. (Barth, 1981, p. 3)
Essential Questions
· What are the four elements of a Christian worldview and how do they influence a Christian approach to medicine, healing, and medical ethics?
· What are the four principles of medical ethics and how are they defined? How can a Christian appropriately use these four principles?
· What is meant by specifying, balancing, and weighing the principles? How does a Christian worldview influence how one defines and uses each of these four principles?
· What is the four-boxes approach to organizing an ethical case study? What is the difference and the relationship between the four-boxes approach, and the four principles of medical ethics?
· What are the four ethical topics that compose the four-boxes approach and what questions does each topic entail? How does the four-boxes approach help solve ethical dilemmas in a case study?
Introduction
Biomedical ethics, or bioethics, is a subfield of ethics concerned with the ethics of medicine and the ethical issues involving the life sciences, particularly those raised by modern technologies, such as stem cell research and cloning. The term medical ethics is closely related to biomedical ethics but is primarily focused on ethical issues raised in the practice of medicine and medical research, such as abortion, euthanasia, and medical treatment decisions (World Medical Association, 2015).
Because the terms biomedical ethics and medical ethics are closely related and involve a great deal of overlapping subject area, they will be used interchangeably to avoid confusion. The study of biomedical ethics and medical ethics presents some of the most complex and controversial challenges in applied ethics. The complexities of dealing with individual patients and the intricacies of modern health care, coupled with the rapid advances being made in medical science, present formidable challenges. For many health care workers, clinical ethical dilemmas will often challenge their own settled positions, especially if they have not taken the opportunity to reflect critically on their own moral presuppositions and how their own intuitive ethical positions may be justified.
When one encounters the many ways the world and even portions of the Christian church respond to ethical issues, it is easy to be tempted to think there are no right or wrong answers. The complexity o ...
Earliest Galaxies in the JADES Origins Field: Luminosity Function and Cosmic ...Sérgio Sacani
We characterize the earliest galaxy population in the JADES Origins Field (JOF), the deepest
imaging field observed with JWST. We make use of the ancillary Hubble optical images (5 filters
spanning 0.4−0.9µm) and novel JWST images with 14 filters spanning 0.8−5µm, including 7 mediumband filters, and reaching total exposure times of up to 46 hours per filter. We combine all our data
at > 2.3µm to construct an ultradeep image, reaching as deep as ≈ 31.4 AB mag in the stack and
30.3-31.0 AB mag (5σ, r = 0.1” circular aperture) in individual filters. We measure photometric
redshifts and use robust selection criteria to identify a sample of eight galaxy candidates at redshifts
z = 11.5 − 15. These objects show compact half-light radii of R1/2 ∼ 50 − 200pc, stellar masses of
M⋆ ∼ 107−108M⊙, and star-formation rates of SFR ∼ 0.1−1 M⊙ yr−1
. Our search finds no candidates
at 15 < z < 20, placing upper limits at these redshifts. We develop a forward modeling approach to
infer the properties of the evolving luminosity function without binning in redshift or luminosity that
marginalizes over the photometric redshift uncertainty of our candidate galaxies and incorporates the
impact of non-detections. We find a z = 12 luminosity function in good agreement with prior results,
and that the luminosity function normalization and UV luminosity density decline by a factor of ∼ 2.5
from z = 12 to z = 14. We discuss the possible implications of our results in the context of theoretical
models for evolution of the dark matter halo mass function.
Phenomics assisted breeding in crop improvementIshaGoswami9
As the population is increasing and will reach about 9 billion upto 2050. Also due to climate change, it is difficult to meet the food requirement of such a large population. Facing the challenges presented by resource shortages, climate
change, and increasing global population, crop yield and quality need to be improved in a sustainable way over the coming decades. Genetic improvement by breeding is the best way to increase crop productivity. With the rapid progression of functional
genomics, an increasing number of crop genomes have been sequenced and dozens of genes influencing key agronomic traits have been identified. However, current genome sequence information has not been adequately exploited for understanding
the complex characteristics of multiple gene, owing to a lack of crop phenotypic data. Efficient, automatic, and accurate technologies and platforms that can capture phenotypic data that can
be linked to genomics information for crop improvement at all growth stages have become as important as genotyping. Thus,
high-throughput phenotyping has become the major bottleneck restricting crop breeding. Plant phenomics has been defined as the high-throughput, accurate acquisition and analysis of multi-dimensional phenotypes
during crop growing stages at the organism level, including the cell, tissue, organ, individual plant, plot, and field levels. With the rapid development of novel sensors, imaging technology,
and analysis methods, numerous infrastructure platforms have been developed for phenotyping.
Richard's aventures in two entangled wonderlandsRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
DERIVATION OF MODIFIED BERNOULLI EQUATION WITH VISCOUS EFFECTS AND TERMINAL V...Wasswaderrick3
In this book, we use conservation of energy techniques on a fluid element to derive the Modified Bernoulli equation of flow with viscous or friction effects. We derive the general equation of flow/ velocity and then from this we derive the Pouiselle flow equation, the transition flow equation and the turbulent flow equation. In the situations where there are no viscous effects , the equation reduces to the Bernoulli equation. From experimental results, we are able to include other terms in the Bernoulli equation. We also look at cases where pressure gradients exist. We use the Modified Bernoulli equation to derive equations of flow rate for pipes of different cross sectional areas connected together. We also extend our techniques of energy conservation to a sphere falling in a viscous medium under the effect of gravity. We demonstrate Stokes equation of terminal velocity and turbulent flow equation. We look at a way of calculating the time taken for a body to fall in a viscous medium. We also look at the general equation of terminal velocity.
Nutraceutical market, scope and growth: Herbal drug technologyLokesh Patil
As consumer awareness of health and wellness rises, the nutraceutical market—which includes goods like functional meals, drinks, and dietary supplements that provide health advantages beyond basic nutrition—is growing significantly. As healthcare expenses rise, the population ages, and people want natural and preventative health solutions more and more, this industry is increasing quickly. Further driving market expansion are product formulation innovations and the use of cutting-edge technology for customized nutrition. With its worldwide reach, the nutraceutical industry is expected to keep growing and provide significant chances for research and investment in a number of categories, including vitamins, minerals, probiotics, and herbal supplements.
Deep Behavioral Phenotyping in Systems Neuroscience for Functional Atlasing a...Ana Luísa Pinho
Functional Magnetic Resonance Imaging (fMRI) provides means to characterize brain activations in response to behavior. However, cognitive neuroscience has been limited to group-level effects referring to the performance of specific tasks. To obtain the functional profile of elementary cognitive mechanisms, the combination of brain responses to many tasks is required. Yet, to date, both structural atlases and parcellation-based activations do not fully account for cognitive function and still present several limitations. Further, they do not adapt overall to individual characteristics. In this talk, I will give an account of deep-behavioral phenotyping strategies, namely data-driven methods in large task-fMRI datasets, to optimize functional brain-data collection and improve inference of effects-of-interest related to mental processes. Key to this approach is the employment of fast multi-functional paradigms rich on features that can be well parametrized and, consequently, facilitate the creation of psycho-physiological constructs to be modelled with imaging data. Particular emphasis will be given to music stimuli when studying high-order cognitive mechanisms, due to their ecological nature and quality to enable complex behavior compounded by discrete entities. I will also discuss how deep-behavioral phenotyping and individualized models applied to neuroimaging data can better account for the subject-specific organization of domain-general cognitive systems in the human brain. Finally, the accumulation of functional brain signatures brings the possibility to clarify relationships among tasks and create a univocal link between brain systems and mental functions through: (1) the development of ontologies proposing an organization of cognitive processes; and (2) brain-network taxonomies describing functional specialization. To this end, tools to improve commensurability in cognitive science are necessary, such as public repositories, ontology-based platforms and automated meta-analysis tools. I will thus discuss some brain-atlasing resources currently under development, and their applicability in cognitive as well as clinical neuroscience.
Salas, V. (2024) "John of St. Thomas (Poinsot) on the Science of Sacred Theol...Studia Poinsotiana
I Introduction
II Subalternation and Theology
III Theology and Dogmatic Declarations
IV The Mixed Principles of Theology
V Virtual Revelation: The Unity of Theology
VI Theology as a Natural Science
VII Theology’s Certitude
VIII Conclusion
Notes
Bibliography
All the contents are fully attributable to the author, Doctor Victor Salas. Should you wish to get this text republished, get in touch with the author or the editorial committee of the Studia Poinsotiana. Insofar as possible, we will be happy to broker your contact.
Toxic effects of heavy metals : Lead and Arsenicsanjana502982
Heavy metals are naturally occuring metallic chemical elements that have relatively high density, and are toxic at even low concentrations. All toxic metals are termed as heavy metals irrespective of their atomic mass and density, eg. arsenic, lead, mercury, cadmium, thallium, chromium, etc.
1. The Word "Bioethics": The Struggle Over Its Earliest Meanings
Warren Thomas Reich
Kennedy Institute of Ethics Journal, Volume 5, Number 1, March 1995, pp.
19-34 (Article)
Published by Johns Hopkins University Press
DOI:
For additional information about this article
Access provided by The University of Lethbridge Library (6 May 2017 16:31 GMT)
https://doi.org/10.1353/ken.0.0143
https://muse.jhu.edu/article/245728
3. KENNEDY INSTITUTE OF ETHICS JOURNAL · MARCH1995
from the start, some major differences—even clashes—between the
Potter understanding and the Hellegers/Georgetown understanding of
bioethics; and (2) the Hellegers/Georgetown approach came to be the
more widely accepted meaning of the term, while Potter's idea of
bioethics remained largely marginalized.
My inquiry has enabled me to validate these two assumptions only
partly, for it has led me to a third, unanticipated, conclusion: that
Hellegers (in contrast to the dominant model offered by the Georgetown
scholars) actually proposed a global approach to bioethics, bringing his
vision much closer to Potter's evolving view than previously has been
acknowledged.
Within months after Potter had introduced his new word "bioethics"
that would embrace within its scope long-range environmental concerns,
the Georgetown institute and scholars initiated a use of the word that
clashed with Potter's already-publicized vision. The Georgetown model1
introduced a notion of bioethics that would deal with concrete medical
dilemmas restricted to three issue-areas: (1) the rights and duties of
patients and health professionals; (2) the rights and duties of research
subjects and researchers; and (3) the formulation of public policy guide-
lines for clinical care and biomedical research.2 For example, the
Institute's original (October 1971) list of bioethical issues proposed for
consideration included: obligations regarding the "mongoloid child"
that has a life-threatening disease; laboratory research directed toward
development of "test-tube babies," and allocation of scarce "artificial
kidney machines" (Institute for Bioethics 1971).
When Georgetown took the term "bioethics" in the narrower direc-
tion of what one Georgetown scholar called a "revitalized study of med-
ical ethics," expanded somewhat beyond the "problems of physicians"
(Walters 1985, pp. 13-14), Potter was frustrated. His frustration and
disagreement were not directed toward Hellegers but toward the
Georgetown model of bioethics more generally. He acknowledged that
the Georgetown issues are part of bioethics, and he even found that a
general explanation of the field that was issued from the Kennedy
Institute was "essentially in general agreement with my original one"
(Potter 1975, p. 2299); but he emphasized that, in contrast to the
Georgetown definition and scope of the field, "my own view of bioethics
calls for a much broader vision" (p. 2300).
Potter's reaction was based on his fear that the Georgetown approach
to bioethics would simply reaffirm the medical profession's inclination
[ 20 ]
4. REICH · THE WORD "BIOETHICS"
to think more in terms of issues of therapy to the neglect of prevention.
Because his field was carcinogenesis, he was aware of the strong link
between medical problems and carcinogens in the environment. Thus,
his holistic way of perceiving health led him to the view that even the
clinical therapist "should be thinking about the need for environmental
ethics" (interview with the author, 31 August 1992).
While the initial clash between the Potter and Georgetown perspec-
tives on the word "bioethics" focused on the scope of the term, more
pervasive differences existed between the two approaches. While Potter
offered probing essays that made an appeal for the development of a
general normative ethic for global health, the Georgetown approach pre-
sented precise philosophical arguments in the area of applied normative
ethics wherein certain ethical principles "may be applied to" special bio-
medical problem areas (Beauchamp and Walters 1978, p. 1). Thus,
whereas Potter (1975, p. 2297) saw bioethics as a new discipline that
would combine scientific and philosophical knowledge, Georgetown
saw bioethics as part of an old discipline—i.e., as a branch of the
already-existing applied ethics (Beauchamp and Walters 1978, p. 49).
The former was convinced of the potentially strong and influential links
between science and ethics (Potter 1971b, pp. 49-53), whereas the latter
emphasized the assumption that ethics differs from science (Beauchamp
and Walters 1978, p. 1).
Epistemologically, Potter regarded the task of bioethics as being
engaged in the search for wisdom—i.e., for the knowledge that would
enable us to make good judgments as to what would constitute physical,
cultural, and philosophical progress toward a valued survival (Potter
1975, p. 2297). The Georgetown model, on the other hand, sought to
"resolve [concrete] moral problems" in the biomedical arena, through
the coherent application of already-established and universally valid eth-
ical principles (Beauchamp and Walters 1978, p. 33).
In sum, Potter's idea of bioethics promoted development of a new
ethic that would guide moral choices for a valued human global survival,
while the Georgetown approach advocated what K. Danner Clouser
(1978, pp. 116, 120) called "the same old ethics"—i.e., "ordinary ethics
applied to the 'bio-realm.'"
It is not surprising that the Georgetown definition of and approach to
bioethics became the dominant one while Potter's idea of bioethics
remained largely marginalized. The biomedical dilemmas that were
labelled bioethical at Georgetown—such as not being allowed to die,
[ 21 ]
5. KENNEDY INSTITUTE OF ETHICS JOURNAL · MARCH 1995
depersonalized medical care, and the like—were issues that were felt
immediately in the lives of many people in the 1970s, while the envi-
ronmental concerns of Potter—e.g., reducing toxic substances in certain
environments—seemed (unfortunately) more remote and complex. The
American public's civil rights mentality of the 1960s and early 1970s—
e.g., the rights of minorities, women, and the handicapped—energized,
both politically and intellectually, the biomedically-oriented bioethics
that was concerned with abuses of the rights of patients, such as the
injection of live cancer cells into nonconsenting elderly patients for
research purposes. At the same time, there was a political urgency to
many of the biomedical issues: consider the groups who warred with
each other over abortion and the use of fetal tissue for research purpos-
es. The media craved the biomedical controversies and federal and state
policymakers wanted answers. Furthermore, when examined systemati-
cally, the clinical and research issues in bioethics provided interesting
topics for courses in high schools, colleges, and professional schools,
which in turn created a demand for bioethics texts and graduate stu-
dents. Thus, intellectual stimulation joined with economic gain tended to
favor the biomedical approach to bioethics.
Substantive philosophical considerations also favored the
Georgetown orientation to bioethics. While Potter's bioethics lan-
guage—spawned in biology, evolutionary theories, and cybernetics—
was probably judged to be excessively biocentric and too untested,
Georgetown's more traditional and familiar language of ethical princi-
ples (such as justice and autonomy), natural law theory, the rules of util-
itarian calculus, and the like were evidently found more congenial to the
educational and policymaking purposes being pursued.
A humanistic flexibility also favored the Georgetown approach.
Potter's tendency to identify the meaning of bioethics with his own high-
ly detailed scientific/philosophical theory on survival tended by defini-
tion to exclude all other theories, concepts, and normative ethical
approaches, in spite of his assertions that he offered his own theory
"more to open the discussion rather than to finalize it" (Potter 1975, p.
2297). The Georgetown approach, while excessively narrowly focused
on rights, duties, and medical issues, was in principle open to a broad
range of concepts and arguments, in particular those that favored clari-
fication in the public forum of policymaking.
Finally, there was some skepticism over whether Potter's thought even
qualified as ethics. For example, Clouser wrote that it would seem odd
[ 22 ]
6. REICH · THE WORD "BIOETHICS"
to call Potter's enterprise "ethics," since it does not tell us whether we
have specific obligations or rights, or whether some environmental ben-
efits outweigh environmental harms. Clouser did concede, however, that
what he called Potter's "applied science"—the use of science to improve
the quality of life—helped to give substance to already existing "derived
moral rules" (see Clouser 1978, pp. 118-19).3
In addition to the foregoing, there were practical academic and insti-
tutional reasons why Potter's understanding of bioethics was marginal-
ized while the Georgetown use of the term prospered. To promote the
success of the Georgetown vision, Hellegers marshalled hitherto
untapped federal and private funding and university resources for oper-
ating expenses and endowed chairs in bioethics. He fostered the need for
medical bioethics in the government agencies and biomedical research
and clinical centers that were seeking to develop ethical and regulative
policies, and he supplied that need. He surrounded himself with accom-
plished scholars in ethics and the biological and social sciences, who
could develop new interdisciplinary methods and publications in
bioethics. And he fostered the creation of a graduate program in philos-
ophy/bioethics to prepare new generations of scholars for the new field
he envisioned.
By contrast, Potter had no special institutional, academic, or financial
tools for promoting his vision. During most of his career he had to
devote himself to research in biochemistry in order to gain tenure, only
writing on bioethics part-time until his acquisition of senior rank and
retirement permitted him to devote more time to it. Without an inter-
disciplinary team of scholars surrounding him, he had to elaborate a phi-
losophy of science without special credentials in that area. He had no
graduate students in bioethics to extend his research and his influence,
and he had no funding or special institutional support to expand his
work in this area (interview with the author, 30 August 1992).
It is noteworthy that the dominance of the Georgetown over the Potter
idea of bioethics was accompanied by a failure on the part of the schol-
ars of the first group to acknowledge the pioneering role of Van
Rensselaer Potter in coining and publishing the word "bioethics," repeat-
edly promoting the establishment of a new field of bioethics, and con-
tributing scholarly writings to the area of the ethics of environmental
health. One notes, for example, that a number of the significant, early
publications on the meaning, scope, and/or origins of the field of
bioethics fail even to mention Potter's role. These include foundational,
[ 23 ]
7. KENNEDY INSTITUTE OF ETHICS JOURNAL · MARCH I99 5
first-of-a-kind works by Reich (1978),4 Callahan (1973), Walters (1975),
Beauchamp and Walters (1978), and Fox (1990), where one might have
expected such an acknowledgement. The omission may be attributable to
the authors' vague and confused impressions about the precise origin of
the word and to the attitude that they were contributing to a field that
was totally different from Potter's. Yet, by contrast, it is remarkable how
frequently foreign-language introductions to and surveys of bioethics
begin with an acknowledgement of the founding role of Potter.
A CONVERGENCE OF GLOBAL VIEWS
I have found that, in one important respect, Potter and Hellegers were
not that far apart. In spite of their different intellectual backgrounds,
professional settings, bioethical interests, and personal/professional
motivations, they each developed an outlook on bioethics that was
"global" in its breadth of concerns.
My analysis of these two pioneers of bioethics has led me to distin-
guish three senses of the word "global," a word that was introduced into
the literature by Potter. A global bioethics could (1) relate to or involve
the entire earth: a worldwide ethic for the good of the world; (2) entail
the comprehensive inclusion of all ethical issues in the life sciences and
health care (both the "biomedical" and the "environmental" issues of
this classic debate); and (3) utilize a comprehensive vision of methods for
approaching those issues: expansively incorporating all relevant values,
concepts, modes of reasoning and disciplines.
Potter's initial and lasting concern was with a bioethics that was glob-
al in the first sense: It focused on worldwide issues affecting the whole
earth. This ethic was an environmental or ecological ethic, in which he
pleaded for attention to a land ethic, a wildlife ethic, a population ethic,
and a consumption ethic, in international perspective (Potter 1971b).
However, as far as I know, Potter did not use the word "global" to
describe this focus of his idea of bioethics.
After the Kennedy Institute established a medical focus for bioethics,
Potter espoused a perspective on bioethics that was global in the second
sense of the term: a bioethics that comprehensively included all the issues
of both visions. Interestingly, he was pushed in this all-inclusive direction
by his own experience as an oncologist. The concerns and health-related
responsibilities of oncologists, he noted, create links between cancer
research, therapy for cancer patients, prevention of cancer from such envi-
ronmental causes as health conditions in the work place (e.g., worker
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8. REICH · THE WORD "BIOETHICS"
exposure to vinyl chloride), agricultural policies (e.g., the use of agricul-
tural lands for tobacco growing), and health education (e.g., instructing
school children on the dangers of smoking) (Potter 1975, pp. 2299, 2301).
When his revised, more comprehensive definition of bioethics did not
catch on, Potter (1992b, p. 2) acknowledged that his original definition
had not clearly indicated that bioethics could designate a broad range of
moral issues—for example, both medical and environmental. In the
meantime, he saw the term "bioethics" become "widely used in the lim-
ited sense of concern solely with the ethical problems connected with the
practice of medicine." For these reasons, 18 years after coining the word
"bioethics," Potter (1988, 1992a) invented the term "global bioethics"
as a way of uniting medical and ecological ethical issues in the one, more
inclusive field of bioethics. Unfortunately, Potter speaks, in this context,
of "the philosophy of global bioethics," in which biomedical and eco-
logical ethical concerns are united under the single banner of his own
notion of "acceptable survival." The objection can be raised that no field
of learning should be defined in terms that are specific to only one the-
ory propounded within that field.
Within the framework of his own theory, Potter is remarkably global
(without using the word in this context) in the third sense—i.e., as man-
ifesting a broad and expansive vision of perspectives, values, concepts,
and disciplines. A key factor that motivated Potter to embrace a broad
vision for science and philosophy, and eventually to advocate the field of
bioethics, was his own frustration as a research oncologist. Decades
devoted to his own research in cell biology and cancer as a concerned
biochemist did not witness the elimination of "the scourge of cancer"
from the human horizon (Potter 1971b, p. viii). He experienced what he
called a "subconscious drive": He was motivated to find an "ordered
disorder" at the cosmic level, to explain the "disorder" he had seen in
the practical aspects of the cancer problem. This, in turn, led him to his
overriding concept of global human survival through progress. The
moral task, then, according to Potter, was to "do research on truth ori-
ented to the future": not only knowledge, but value judgments that will
be significant for future generations. But "since no individual knows the
criteria that are most appropriate for judging actions oriented to the
future, we must be disposed to transcend the boundaries of the disci-
plines, ...[and] develop pluralistic approaches arising from the work of
interdisciplinary groups" (Spinsanti, 1994, p. 237). Consequently, Pot-
ter's methods were global in scope.
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10. REICH · THE WORD "BIOETHICS"
bioethics with the pursuit of global issues in international health and
population dynamics.
Hellegers frequently introduced global issues into bioethics by arguing
that the profound changes being experienced in clinical medicine led in
that direction. These changes deeply altered public expectations, which
in turn expanded the issues and values that should characterize medical
ethics and the nascent field of bioethics in the medical context.
For example, the shift from a private setting to team care expanded
professional responsibilities and patient expectations; increasing diagno-
sis of conditions that are hyper- or hypo- required a judgment of what is
significant for health—a judgment that had to rely on epidemiology, bio-
statistics, and values; medicine increasingly served the purpose of ren-
dering individuals more amenable to good functioning in society—a psy-
chosomatic thrust that had been stimulated by psychiatry; medicine was
increasingly called on simply to render technological services not direct-
ly related to pathological conditions, such as plastic surgery and abor-
tion; more attention was being given to public health and the prevention
of disease, which required the intersection of microbiology with clinical
medicine; and the goal of medicine was regarded in some quarters as
enabling all persons to achieve a sense of well-being (the World Health
Organization definition of health).
These changes in the expectations of medicine, Hellegers argued, shift
the moral questions of medicine from the traditional dyad of powerful
physician/vulnerable patient to the area of "social ethical calculations"
regarding the major values that will guide the entire enterprise of medi-
cine where broad choices of health, quality of life, and allocation must
be made (Hellegers 1975; see also 1977).
In his inaugural bioethics column, he acknowledged that his approach
to bioethics was "somewhat different." While others who might write
on bioethics would restrict themselves to specific issues of conflict such
as abortion and "death with dignity," Hellegers said that his concern
was the overriding question of the effect of medical technology on soci-
ety. He saw the profession of medicine as being not simply in the service
of the sick but as morally embedded in a concern for mankind. Thus, he
devoted his bioethics columns to "issues involving medicine and biology
and their possible consequences for society" (Hellegers 1973).
Hellegers' perspective on the meaning of bioethics was global in the
third sense of the term—embracing an expansive vision of values, meth-
ods, and disciplines. Describing some of the sharply drawn features of a
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12. REICH · THE WORD "BIOETHICS"
shaped morally and intellectually by the milieu that stimulates its devel-
opment. For example, its pervasive concern over the survival of the indi-
vidual human in the critical care setting drains the moral energies of
bioethics from the larger issues of human survival and the quality of life
and health in demographic and environmental perspectives. Furthermore,
without a global perspective on health and the life sciences, the work of
bioethicists more easily becomes defined by medical institutions. For
example, excessive concentration of bioethical energy on clinical ethics
within an academic health center easily confirms these institutions'
sociomedical bias of excluding public and preventive health of all humans
from the purview of their committed moral concerns.
On the other hand, a more global understanding of bioethics—one sit-
uated in the larger vision of the well-being of human and other life—offers
a broader interpretive setting. Its richer set of concerns supplies both a
framework for the search for meaning and a built-in basis for critique.
Consequently, it is my conviction that, in light of its origins, bioethics
is best defined in its global sense, as the ethics of the life sciences and
health care. This means that bioethics goes beyond ethical issues in med-
icine to include ethical issues in public health, population concerns,
genetics, environmental health, reproductive practices and technologies,
animal health and welfare, and the like. This broader scope, with which
both Potter and Hellegers agreed, was the original intent of the Hastings
Center, which from the start was interested in "ethics and the life sci-
ences." Starting in 1972 the Encyclopedia of Bioethics advocated an
approach to bioethics that is global in both scope and range of ethical
sources. Noting that the word "bioethics" is a composite derived from
two Greek words—bios (life; hence life sciences) and ethike (ethics), it
established a broad scope for the field in the following definition, which
became standard in many parts of the world: "the systematic study of
human conduct in the area of the life sciences and health care, insofar as
this conduct is examined in the light of moral values and principles"
(Reich 1978, p. xix).6 In 1990, all 14 Area Editors of the revised edition
of that encyclopedia unanimously confirmed and decided to strengthen
this global scope of bioethics.
Individual bioethics scholars and institutes are not likely to agree on
the scope of the term "bioethics." However, it is my conviction that, at
least in documents that comment on the field in general, it would be
preferable to make the following distinction in the title of this discipline:
to use the term "bioethics" in its original, global sense, as referring to
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13. KENNEDY INSTITUTE OF ETHICS JOURNAL · MARCH1995
the ethics of the life sciences and health care; and then use adjectives to
specify particular areas of concern within bioethics. For example, one
might speak of medical bioethics, environmental bioethics, clinical
bioethics, or nursing bioethics without implying, with these terms, any
particular approach.7 This terminology could serve both to draw clearer
boundaries of interest and to foster disciplinary links between the glob-
al and the narrower uses of the term "bioethics."
CONCLUSION
The word "bioethics" has a power that has shaped the field. Tristram
Engelhardt, in his foreword to Potter's Global Bioethics (1988), pointed
out that a new word can be the source of power and usefulness and can
take on a life of its own. "An apt word can assemble a rich set of images
and meanings and thus help us to see relations between elements of real-
ity that were previously separated in our vision and thought of only as
disparate.... This has been the case with 'bioethics.'... The word
'bioethics' [has done] brilliant service in bringing together a wide cluster
of important cultural concerns. The term [is] profoundly heuristic"
(Engelhardt, in Potter 1988, pp. vii-viii).
The power of the word "bioethics" was such that the word itself
played a major role in stimulating the origins of the field that bears the
name. In the 1950s and 1960s, public and scholarly discussions of the
ethical aspects of "the new biology," scarce and unusual medical tech-
nologies, and abuses in human research constituted the prehistory of
bioethics. They set the stage and initiated dialogue; but it required a
more powerful humanistic stimulus to create a new field. The word
"bioethics" itself was at the core of that stimulus. Consequently, I
believe our colleagues at the Lanza Institute in Padua, Italy, were correct
when they sponsored a symposium in 1990 on the twentieth anniversary
of the birth of bioethics, a landmark date that coincided with the twen-
tieth anniversary of the birth of the word "bioethics" (Viafora 1990).
The field of bioethics originated with the word "bioethics," in part
because the word itself symbolized and stimulated an unprecedented
interaction of biological, medical, technological, ethical, and social
problems and methods of thinking. Significantly, the word "bioethics"
played a major role in creating a new forum and a new platform from
which to speak, displacing the suspicions of sectarianism and religious
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14. REICH · THE WORD "BIOETHICS"
ideology previously suggested to the public mind by the word "ethics."
The word had the wonderfully innovative effect of creating an accept-
able secular terrain—both within academe and in the public forum—
where scientific, health-related, religious, philosophical, and social and
political ideas could meet and create a new, multidisciplinary mode of
inquiry. This new approach was precisely the core of what both Potter
and Hellegers had envisioned. Furthermore, the seductive word
"bioethics" catapulted energies in new directions. It rallied intellectual
and moral energies seen only occasionally in a single generation. It has
provided a "hook" to grab the interests and financial support of gov-
ernments and private organizations (Eunice Kennedy Shriver, interview
with the author, 1 October 1992). Finally, at the time of the 1992 Seattle
conference, it was the word "bioethics" that rallied people to survey and
revisit their shared history of a new and distinctive field of inquiry.
I referred, in my introduction, to "the bilocated birth" of the name of
this field. I want to conclude with another birthing metaphor, because my
inquiry has led me to feel deeply chagrined at the way in which the twins
were separated at birth. I believe it would be a fruitful endeavor to reunite
the bioethics twins that have been separated since birth. This article has
demonstrated one result of such a reunion: its reuniting of the views of
two founding pioneers of bioethics has revealed a shared vision of the
global dimensions of bioethics in both the Potter and the Hellegers legacy.
At the very least, a conversation between the bioethics twins should
prompt us to reconsider the orientation of bioethics,8 stimulate our per-
ception of what issues count, clarify the implications of excluding some
issues and voices in the life sciences and health care, and illuminate the
intellectual and moral culture that can shape our understanding of bio-
ethics. That sort of dialogue would be a fitting tribute to both the Potter
legacy and the Hellegers legacy in the naming of the field of bioethics.
I would like to acknowledge the assistance of Jon Reynolds, Mary Coutts, Kevin Keith,
and Lauren Deichman in the preparation of this article; and Courtney S. Campbell for
his helpful comments.
NOTES
1. By "the Georgetown model" I am speaking of the general thrust for which
the Kennedy Institute of Ethics has become known. In fact, there neither is
nor was a total homogeneity of approaches at the Institute.
2. See Tom L. Beauchamp and LeRoy Walters (1978, Preface and pp. 49-51).
[ 3i ]