This document provides guidance on when and how to effectively interrupt a conversation. It discusses interrupting with agreement, disagreement, encouragement, questions, and permission. Key tips include interrupting when the other person has finished their main point, is slowing down, or pauses. It's best to let others interrupt when you've had a fair turn speaking, made your single point, or they are signaling they want to speak. The document advises not interrupting when thinking of something to say, if the other person is aroused emotionally, or if they have more power in the conversation.