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Human Respiration:

Ventilation

      03/14/12 23:12   cottingham
Human Respiration
   Involves the process of:

a) cellular respiration:
  Glucose + O2  H2O + CO2 + 36 ATP’s
b) gas exchange:
       exchange of gases between the internal
  and external environment with the use of
  lungs
c. ventilation - breathing
                   03/14/12 23:12       cottingham
Ventilation System
                  why do we need it!?
   adequate lung ventilation is essential to
    gas exchange
   ventilation provides a continual supply of
    fresh air to the lungs needed to
    maintain a large concentration gradient
    for gas exchange >> surface of the
    alveoli
   O2 must be delivered regularly
   CO2 must be quickly eliminated
                      03/14/12 23:12       cottingham
(I) Human Respiratory System

   Composed   of a network of
   passageways which permits
  air to flow from the external
    environment and into the
               lungs

               03/14/12 23:12   cottingham
The Upper Respiratory Tract




         03/14/12 23:12       cottingham
Nasal Cavity
 The  nose
 Lined with a ciliated
  mucus membrane
 The cilia and mucus:

     1. Filters air
     2. Warms air
     3. Moistens air
                03/14/12 23:12   cottingham
Pharynx
 Known   as the
  throat region
 It is an area
  in which both
  air and food
  pass through
              03/14/12 23:12   cottingham
Larynx
   Humans
       use the larynx as a
        voice box

       contains vocal cords
        that vibrate and
        produce sound as air
        passes through




                        03/14/12 23:12   cottingham
Epiglottis
A  cartilaginous
  flap
 It “covers” the
  trachea when
  swallowing food


              03/14/12 23:12   cottingham
Trachea
 Known as the windpipe
 Kept open by rings of
  cartilage
 Lined with a ciliated
  mucus membrane
 One cigarette
  paralyzes the cilia for
  20 minutes
                  03/14/12 23:12   cottingham
Lung




03/14/12 23:12   cottingham
Bronchi
 Bronchus = singular
 Trachea divides into two major
  divisions known as bronchi
 The bronchi contain cartilage
  rings as well
 The bronchi subdivide many times
  forming smaller tubules known as
  bronchioles
             03/14/12 23:12     cottingham
Bronchioles
 Lack   cartilage
  rings
 Tiny bronchioles
  subdivide and
  terminate (end)
  with structures
  known as alveoli
               03/14/12 23:12   cottingham
Alveoli




 03/14/12 23:12   cottingham
Alveoli
   Are thin: single layer of cells – easy
    diffusion
   Moist: helps gases to dissolve before
    passing thru membranes/
   Alveoli increase surface area for gas
    exchange
   Rich in blood vessels: O2 diffuses into
    the blood from the alveoli and CO2
    and water diffuse out of the blood
    and into the alveoli
                   03/14/12 23:12          cottingham
(II) Breathing Process
    Inhaling – Inspiration
    Exhaling – Expiration

    Lungs are highly elastic (stretchable)
    Thoracic Cavity is sealed
    Atmospheric Pressure Constant
    Atmospheric Pressure forces air into the lungs:
        Volume Inc. / Pressure Dec. = Inhale
        Volume Dec. / Pressure Inc = Exhale
 4 sets of MUSCLES that control breathing include:


                           03/14/12 23:12              cottingham
Diaphragm and Abdominal
               Muscles
 Diaphragm contracts –
  flattens dome – Inhale
 Abdominal muscles relax



   Diaphragm relaxes –
    abdominal muscles
    contract - Exhale

                  03/14/12 23:12   cottingham
Intercostal Muscles
   External Intercostals –
       Attached to rib cage
       Contracts to move rib cage up and out

       Inhale



   Internal Intercostal
       Attached to rib cage
       Contracts to move rib cage down and in

       Exhale




                      03/14/12 23:12             cottingham
03/14/12 23:12   cottingham
II – Breathing Process




        03/14/12 23:12   cottingham
III – Gas Exchange




      03/14/12 23:12   cottingham
(III) Gas Exchange
•   High Concentration gradient
    needed.
•   In the blood, hemoglobin binds
    with oxygen from the alveoli to
    form oxyhemoglobin (HbO2)
•   Carbon dioxide is carried primarily
    in the plasma of the blood in the
    form of bicarbonate ions (HCO3)
Lung Attack – Gas Exchange
                        03/14/12 23:12   cottingham
THE END




03/14/12 23:12   cottingham

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Human respiration ib master

  • 1. Human Respiration: Ventilation 03/14/12 23:12 cottingham
  • 2. Human Respiration  Involves the process of: a) cellular respiration: Glucose + O2  H2O + CO2 + 36 ATP’s b) gas exchange: exchange of gases between the internal and external environment with the use of lungs c. ventilation - breathing 03/14/12 23:12 cottingham
  • 3. Ventilation System why do we need it!?  adequate lung ventilation is essential to gas exchange  ventilation provides a continual supply of fresh air to the lungs needed to maintain a large concentration gradient for gas exchange >> surface of the alveoli  O2 must be delivered regularly  CO2 must be quickly eliminated 03/14/12 23:12 cottingham
  • 4. (I) Human Respiratory System  Composed of a network of passageways which permits air to flow from the external environment and into the lungs 03/14/12 23:12 cottingham
  • 5. The Upper Respiratory Tract 03/14/12 23:12 cottingham
  • 6. Nasal Cavity  The nose  Lined with a ciliated mucus membrane  The cilia and mucus: 1. Filters air 2. Warms air 3. Moistens air 03/14/12 23:12 cottingham
  • 7. Pharynx  Known as the throat region  It is an area in which both air and food pass through 03/14/12 23:12 cottingham
  • 8. Larynx  Humans  use the larynx as a voice box  contains vocal cords that vibrate and produce sound as air passes through 03/14/12 23:12 cottingham
  • 9. Epiglottis A cartilaginous flap  It “covers” the trachea when swallowing food 03/14/12 23:12 cottingham
  • 10. Trachea  Known as the windpipe  Kept open by rings of cartilage  Lined with a ciliated mucus membrane  One cigarette paralyzes the cilia for 20 minutes 03/14/12 23:12 cottingham
  • 11. Lung 03/14/12 23:12 cottingham
  • 12. Bronchi  Bronchus = singular  Trachea divides into two major divisions known as bronchi  The bronchi contain cartilage rings as well  The bronchi subdivide many times forming smaller tubules known as bronchioles 03/14/12 23:12 cottingham
  • 13. Bronchioles  Lack cartilage rings  Tiny bronchioles subdivide and terminate (end) with structures known as alveoli 03/14/12 23:12 cottingham
  • 15. Alveoli  Are thin: single layer of cells – easy diffusion  Moist: helps gases to dissolve before passing thru membranes/  Alveoli increase surface area for gas exchange  Rich in blood vessels: O2 diffuses into the blood from the alveoli and CO2 and water diffuse out of the blood and into the alveoli 03/14/12 23:12 cottingham
  • 16. (II) Breathing Process  Inhaling – Inspiration  Exhaling – Expiration  Lungs are highly elastic (stretchable)  Thoracic Cavity is sealed  Atmospheric Pressure Constant  Atmospheric Pressure forces air into the lungs:  Volume Inc. / Pressure Dec. = Inhale  Volume Dec. / Pressure Inc = Exhale 4 sets of MUSCLES that control breathing include: 03/14/12 23:12 cottingham
  • 17. Diaphragm and Abdominal Muscles  Diaphragm contracts – flattens dome – Inhale  Abdominal muscles relax  Diaphragm relaxes – abdominal muscles contract - Exhale 03/14/12 23:12 cottingham
  • 18. Intercostal Muscles  External Intercostals –  Attached to rib cage  Contracts to move rib cage up and out  Inhale  Internal Intercostal  Attached to rib cage  Contracts to move rib cage down and in  Exhale 03/14/12 23:12 cottingham
  • 19. 03/14/12 23:12 cottingham
  • 20. II – Breathing Process 03/14/12 23:12 cottingham
  • 21. III – Gas Exchange 03/14/12 23:12 cottingham
  • 22. (III) Gas Exchange • High Concentration gradient needed. • In the blood, hemoglobin binds with oxygen from the alveoli to form oxyhemoglobin (HbO2) • Carbon dioxide is carried primarily in the plasma of the blood in the form of bicarbonate ions (HCO3) Lung Attack – Gas Exchange 03/14/12 23:12 cottingham