Herpes simplex virus (HSV) is a viral disease that can cause cold sores or genital herpes. It was first recognized by Hippocrates in ancient Greece. There are two types - HSV-1 typically causes oral herpes while HSV-2 typically causes genital herpes, though either type can cause infection in either area. The virus is usually spread through skin-to-skin contact and can remain dormant in the body between outbreaks. While most infections are asymptomatic, symptomatic infections cause lesions and sores that can be treated but not cured.

1. HERPES SIMPLEX
INFECTION
PREPARED BY:
HANA ABDULSALAM , SAKAR LUQMAM, AREZ ABUBAKR , AVIN ANWAR

2. OUTLINE:
• History of HSV
• Types of HSV
• sign & symptom
• prevention
• Pathophysiology
• Complications
• treatment

3. INTRODUCTION:
Herpes simplex: is a viral disease caused
by the herpes simplex viruses

4. HISTORY:
researchers have identified the evolutionary origins of human herpes
simplex virus split from chimpanzees 6 million years ago while the
latter jumped from ancient chimpanzees to ancestors of modern
humans – Homo erectus – approximately 1.6 million years ago.

5. HISTORY:
French scientist Emile Vidal
confirmed that herpes is a
contagious skin condition
and was transmitted from
person to person.
VIRUSES ARE DISCOVERED
BY DIMITRI IVANSKI IN
RUSSIA
460-370 BCE Herpes is
formally recognized by
Hippocrates as a
"Creeping and Crawling"
lesion.

6. HISTORY:
14 – 37 Roman Physician Celsus irons
the sores to prevent spread.
1939-FRANK BURNET
DETERMINES THAT HERPES
CAN REMAIN DORMANT IN
NON-INFECTED AREAS.

7. INTRODUCTION:
• Herpes simplex viruses are ubiquitous,
host-adapted pathogens that cause a
wide variety of disease states
• HSV belongs to the alpha herpes virus
group. It is an enveloped virus that is
approximately 160 nm in diameter with a
linear, double-stranded DNA genome.
• up to 80% of herpes simplex infections
are asymptomatic. Symptomatic
infections can be characterized by
significant morbidity and recurrence.

8. OUTLINE :
• Types of HSV
• How it spread ?
• Sign & symptom
• Risk factor
• prevention

9. TYPES OF HERPES VIRUS :
HSV-1: Also known as oral herpes, this type can cause cold sores and
fever blisters around the mouth and on the face.
HSV-2: This type is generally responsible for genital herpes outbreaks.

10. ORAL & GENITAL
HERPES:

11. How it spread ?

12. ORAL HERPES

14. GENITAL HERPES:

15. RISK FACTOR:
1- Are a woman. Women are more likely to have genital
herpes than are men. The virus is sexually transmitted more
easily from men to women than it is from women to men.
2- Have multiple sexual partners. Each additional sexual
partner raises your risk of being exposed to the virus that
causes genital herpes.

16. PREVENTION :
1- Use, or have your partner use, a latex condom during every
sexual contact
2- Avoid intercourse if either partner has an outbreak of herpes in
the genital area or anywhere else
3- Avoid touching an open herpes sore or something that has been
in contact with the herpes virus, such as infected razors, towels,
dishes, and other shared items.

17. PATHOPHYSIOLOGY:

18. PAYHOPHYSIOLOGY:

19. PATHOPHYSIOLOGY:

21. COMPLICATIONS :

26. TREATMENT :

27. RESOURCE :
• www.osmosis.org www.myoclinic.org www.medlineplus.gov