Herpes simplex virus (HSV) encompasses two types: HSV-1, causing oral herpes, and HSV-2, responsible for genital herpes, both transmitted through close contact. Approximately 16.2% of people aged 14-49 in the U.S. are affected, with higher prevalence among women and African Americans. While mild cases may resolve without treatment, severe infections can lead to complications, necessitating antiviral medications.