This document provides an overview of heart transplantation, including: - A brief history of heart transplantation from early experiments in the 1960s to advances like immunosuppressant drugs and ventricular assist devices. - Stages of heart failure from risk factors to end-stage disease requiring specialized interventions. - Key details on the surgical procedure for heart transplantation and long-term patient care, including monitoring and treating rejection, infection, and other complications. - India has conducted around 70 heart transplants since 1994, though availability remains limited due to costs and immunosuppressant drug expenses.