This document provides guidance on evaluating and treating various common hand and finger injuries. It discusses evaluating and repairing lacerations, treating tendon damage with either immediate closure or later repair, and immobilizing fractures and dislocations. It also outlines treating various infections like paronychia, felon, and cellulitis with incision and drainage or antibiotics. Burns are treated with wound cleaning and topical agents. Miscellaneous sections cover removing stuck rings and "ring avulsion."
Hand rehabilitation following flexor tendon injuriesAbey P Rajan
hand rehabilitation following flexor tendon injuries include introduction, clinical anatomy, tendon nutrition, tendon healing, post op. management, special cases, summary
Hand rehabilitation following flexor tendon injuriesAbey P Rajan
hand rehabilitation following flexor tendon injuries include introduction, clinical anatomy, tendon nutrition, tendon healing, post op. management, special cases, summary
Injuries to a ligament are common, especially during athletic activity. Ligaments in the ankle, knee, and wrist are consistently in action during athletic activity and thus are under a lot of stress.
Dr. Bharani Kumar Dayanandam is a prominent Orthopaedic Surgeon providing a wide range of treatments for Shoulder Injuries in Chennai, India
Visit us @ https://www.chennaiorthopaedics.com
Hoffa's Fracture: Diagnosis, management & New Classification System by BAGARI...Vaibhav Bagaria
Hoffa's Fracture - coronal split fracture of distal femur, its diagnosis, management strategy, a new classification and tips and tricks of management. First described Hoffa, a new classification system by Bagaria et al helps plan the surgery for these tricky fracture. The most crucial step is not to miss these fractures in ER.
Injuries to a ligament are common, especially during athletic activity. Ligaments in the ankle, knee, and wrist are consistently in action during athletic activity and thus are under a lot of stress.
Dr. Bharani Kumar Dayanandam is a prominent Orthopaedic Surgeon providing a wide range of treatments for Shoulder Injuries in Chennai, India
Visit us @ https://www.chennaiorthopaedics.com
Hoffa's Fracture: Diagnosis, management & New Classification System by BAGARI...Vaibhav Bagaria
Hoffa's Fracture - coronal split fracture of distal femur, its diagnosis, management strategy, a new classification and tips and tricks of management. First described Hoffa, a new classification system by Bagaria et al helps plan the surgery for these tricky fracture. The most crucial step is not to miss these fractures in ER.
Flexor tendons - enclosed by synovial sheaths.
Tendons - blood supply through synovial folds known as vincula, each
tendon having two, vincula longa and vincula brevia.
The sheath of the little finger is continuous with the ulnar bursa covering
the flexor tendons in the palm.
The flexor pollicis longus is covered by a single sheath throughout, the
radial bursa.
Synovial sheaths can be infected producing tenosynovitis. Infection can
spread throughout the sheath. Infection of the sheath of the little finger can thus spread up the distal aspect of the forearm into the space of Parona.
This PPT is mainly for the III yr MBBS - Students for whom this topic is important. Moreover mainly day today clinical practice practising doctors will come across these types of cases.
Hand Infections by Dr Rogers Ntambi.
This power point presentation is about infections of the hand, relevant anatomy, epidemiology, investigations and treatment options.
The deep palmar infections, webspace, space of parona and other hand infections have been included.
Some atypical hand infections have also been included
Plastic surgery and Orthopedics surgery approaches have also been shown.
Solitary oral ulcers and systemic diseasesDr. Harsh Shah
A brief overview of different ulcerative lesions seen in the oral cavity linked to the dangerous systemic diseases and preventive measures for the disease before it turns lerhal
SDDCH, Parbhani
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
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25. Treatment
• Closed manipulation and
Plaster cast
• Closed manipulation &
percutaneous fixation
• Open reduction and
internal fixation
26. Fracture metacarpals
• All ages
– Fracture through the base
– Fracture to the shaft
– Fracture to the neck
• Boxer’s fracture
• Auto immobilisation
• Dorsal slab
27. Fracture phalanges
• Fall of heavy object or crush injury
• Undisplaced
Displaced
• Strapping
• Open reduction
31. Paronychia
• infection of the finger that involves the tissue
at the edges of the fingernail
• superficial and localized to the soft tissue and
skin
• most common bacterial infection seen in the
hand ( staph; strep).
32. Paronychia treatment
• wound care alone.
• collection of pus - drain.
– a simple incision over the collection of pus to allow
drainage.
– scalpel may be inserted along the edge of the nail to
allow drainage.
– If the infection is large, a part of the nail may be
removed.
• oral antibiotic.
• wound care at home.
33. Felon
• infection of the fingertip.
• This infection is located in the fingertip pad
and soft tissue associated with it.
34. Felon treatment
• incision and drainage
» incision will be
made on one or
both sides of the
fingertip.
» break up the
compartments
» gauze will be
placed into the
wound to aid
the initial
drainage.
» flush out with a
sterile solution
• antibiotics.
35. Herpetic whitlow
• infection of the fingertip area caused by
herpes simplex virus type I or II
• This is the most common viral infection of the
hand.
• This infection is often misdiagnosed as a
paronychia or felon.
36. Herpetic whitlow treatment
• Antiviral drugs
• Pain medication.
• wound must be properly protected to prevent
a secondary bacterial infection
• Incision and drainage is not recommended.
37. Cellulitis
• superficial infection of the skin and underlying
tissue.
• usually on the surface and does not involve
deeper structures of the hand or finger.
• Staph and strep.
39. Infectious flexor tenosynovitis &
Deep space infection
• infection involves the tendon sheaths and
deep spaces
• penetrating trauma that introduces bacteria
• surgical emergency and will require rapid
treatment with IV antibiotics.
40. Kanavel’s cardinal signs
• intense pain
– along the course of tendon with extension
– this is the earliest and most important sign
• flexion posture
• uniform swelling
• percussion tenderness along the course of the
tendon sheath
47. • Wrap the dental floss around your finger, up
to your knuckle
48. • Unwind the dental floss, beginning at the
bottom of the finger
49. Do’s & Don’ts
Do’s
Don’ts
Examine hand carefully
Do not incise every infected digit
Think of other diagnosis
Do not make puncture incisions
Wait for abcess to localize
Do not injure digital vessels or nerves
Place adequate depth and length of
incisions
Do not place incisions crossing the
creases
Immobilise, elevate the hand
Do not close bite wounds
Antibiotics & proper dressings
Do not forget pus culture and
sensitivity
Editor's Notes
Edward Hallaran Bennett (9 April 1837, Charlotte Quay, Cork – 21 June 1907, Dublin) was an Irish surgeon remembered for describing Bennett's fracture. He studied at Trinity College, Dublin of theUniversity of Dublin, graduating M.Ch. in 1859 and M.D. in 1864. He was professor of anatomy and surgery at Trinity College from 1873-1906. He studied fractures, dislocations and bone diseases, recording them at the Pathology Museum at Trinity College. He described his eponymous fracture at the British Medical Association meeting in Cork in 1880.[1] He is said to have introduced antiseptictechnique to Dublin, and became president of the Royal College of Surgeons in Ireland.[2]