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Anatomical challenges
           Spasm, loops, tortuosity

            Ian C Gilchrist, MD, FACC, FSCAI
                    Professor of Medicine
                   Heart & Vascular Institute
             Penn State/Hershey Medical Center
                         Hershey, PA

Duke Master 2011
CME Disclosure Statement




          Nothing      Duke Master 2011
Challenges in the Vasculature


                                                           Anatomic Variability
                                                           Vascular Disease
                                                           Iatrogenic Complications



http://www.ohcaptain.com/2010/05/insights-from-road.html
                                                                              Duke Master 2011
The “Normal” Arm




                   Duke Master 2011
Challenge #1: Anatomical Variability

                           Expect variability
       1540 patients-96.8% success, high-volume radial operators, United Kingdom


                                                                     Catheter in accessory radial




                                                                                Brachial artery


  Radial Loop                       Tortuosity                            Accessory Radial
    (2.3%)                           (2.0%)                                   (7.0%)
      Anatomic variation associated with >3/4 of procedural failures

                           Lo, Nolan et al, Heart 2009;95:410-415.                      Duke Master 2011
Normal Arm Arterial System

                                                                                   Axillary
                                                                                   Artery

  Biceps Brachii
     Muscle
                                                                       Brachial
                                                                        Artery
Brachioradialis
   Muscle

      Radial                                            Ulnar
      Artery                                            Artery




                  Adapted from Jelev L, Cardiovasc Intervent Radiol 2008;31:1008
                                                                                              Duke Master 2011
Normal Arm Angiogram

    Radial Artery




  Ulnar Artery                            Brachial Artery


          J Invasive Cardiol. 2010;22:536–540
                                                            Duke Master 2011
Varied Radial Connections
       Unusual courses, no effect on passage




  Radial-Axillary
    Junction
                                Radial-Brachial
                                  Junction                                 Superficial Radial
                                                                           With High Junction



          Adapted from Jelev L, Cardiovasc Intervent Radiol 2008;31:1008
                                                                                 Duke Master 2011
High Axillary Junction




     J INVASIVE CARDIOL 2010;22:536–540
                                          Duke Master 2011
High Radial Junction with Crossover


        No crossover




                                                                Crossover:
                                                                  Potential for difficult
                                                                      passage &
                                                                     complications
           Adapted from Jelev L, Cardiovasc Intervent Radiol 2008;31:1008
                                                                               Duke Master 2011
Spectrum of Crossover



                                        Tight Fit


                                                                     Tight Turn




    Adapted from Jelev L, Cardiovasc Intervent Radiol 2008;31:1008
                                                                         Duke Master 2011
Angiogram: Accessory Radial


Accessory or remnant
    radial artery




  Large crossover
       “loop”




                       Lo, Nolan et al, Heart 2009;95:410-415.   Duke Master 2011
Radial Loops




J Invasive Cardiol 2010;22:536–540




                                     Adapted from Jelev L, Cardiovasc Intervent Radiol 2008;31:1008
                                                                                                      Duke Master 2011
Axillary/Subclavian Loops




          Icg/HMC Cath Lab




                             Duke Master 2011
Challenge #2: Vascular Disease



        Atherosclerotic
         Vasospastic




                          Duke Master 2011
Atherosclerotic Disease

Calcific arteritis
Arterial stenosis
…but don’t confuse with spasm
Maybe resolved with angioplasty
…if in doubt, change access site
                                   Duke Master 2011
Vasospastic Disease

Young, anxious, female, cold
Raynaud-like Syndromes



  Treat expectantly before symptoms
Severe cases = consider femoral access

                                         Duke Master 2011
Challenge #3: Iatrogenic Disease

   •   Post-Trauma
   •   Radiation
   •   Spasm
   •   Dissection
   •   Perforation
   •   Chronic injury

                            Duke Master 2011
Post-Brachial Cut down




         Icg/HMC Cath Lab


                            Duke Master 2011
Overcoming Challenges


Expect variability,
…have a plan before you start
…enjoy the challenge
…learn to problem solve


                                Duke Master 2011
Solution: Plan for Success

1. Well positioned wrist/relaxed patient
2. Micropuncture needle access
3. Prevent spasm & anticoagulate
4. Use your wire as a friend
5. If in doubt take a picture
6. Maintain central access with your wire

The Radial Is Not a Small Femoral Artery
                                            Duke Master 2011
Solution: Failure of Wire to Advance
        during initial access
 1. Insert sheath to gain partial access
   – Confirm arterial access
   – Treat spasm
 2. Load hydrophilic .035” wire in catheter & try
    to advance into central system
 3. If successful, advance vascular sheath in
    place over cardiac catheter & advance
    coronary catheter.

                                             Duke Master 2011
Solution: Hydrophilic Wire Fails to
            Advance?

1. Look under fluoroscopy at position
2. Obtain limited angiogram to define the
   anatomy
3. Twisting wrist may straighten forearm
   vessels, while a deep breath may change
   more proximal arteries
4. Consider smaller flexible wires, the other
   radial artery, the ulnar artery, or even the
   femoral
                                             Duke Master 2011
Solution: Wire is your friend

• Maintain wire or catheter position as central
  as possible (don’t retreat)
• Use a standard .035” angiographic wire to
  hold position or help reposition catheters
• Exchange over a long wire or “jet” exchange
  over standard length wires

         Do Not Retreat from Success
                                            Duke Master 2011
Solution: Catheter “Jetting”

1. Start with catheter in ascending aorta
2. Pass .035” wire (not hydrophilic) into catheter
3. Fix wire in place & back catheter to end of wire
4. Attached 10cc syringe with fluid on catheter
5. Forcefully inject while pulling “jetting” catheter off
   wire until free from access sheath
6. Confirm wire still in central aortic position
                   Hoorntje JCA. Cathet Cardiovasc Diagn 18:284, 1989.

                                                                         Duke Master 2011
Returning with Next Catheter

1. Confirm wire is still in ascending aorta
2. Advance flushed catheter over wire until wire
   exits catheter’s hub
   – Ectopy indicates wire pushed into ventricle
   – Fluid should drip from catheter as the wire
     displaces flush, if not, wire may have prolapsed
     down descending aorta
3. Remove wire and continue procedure

                                                   Duke Master 2011
Solution: Spasm during procedure

Use more pharmacology
Use smaller French equipment
Minimize mechanical manipulation
Wipe wire, flush catheters, and “jet” with
antispasmodic agents (nitrates, Ca++
blockers)

         Warm the arm or room
                                             Duke Master 2011
Summary

 Variety is part of normal arm vasculature
 Makes radial “fun”
 Potentially a cause for failure, but…
 Challenges can be overcome resulting in success


Expect it, have a plan, you will succeed

                                             Duke Master 2011
Thank you




            Duke Master 2011

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Gilchrist IC 201110

  • 1. Anatomical challenges Spasm, loops, tortuosity Ian C Gilchrist, MD, FACC, FSCAI Professor of Medicine Heart & Vascular Institute Penn State/Hershey Medical Center Hershey, PA Duke Master 2011
  • 2. CME Disclosure Statement Nothing Duke Master 2011
  • 3. Challenges in the Vasculature Anatomic Variability Vascular Disease Iatrogenic Complications http://www.ohcaptain.com/2010/05/insights-from-road.html Duke Master 2011
  • 4. The “Normal” Arm Duke Master 2011
  • 5. Challenge #1: Anatomical Variability Expect variability 1540 patients-96.8% success, high-volume radial operators, United Kingdom Catheter in accessory radial Brachial artery Radial Loop Tortuosity Accessory Radial (2.3%) (2.0%) (7.0%) Anatomic variation associated with >3/4 of procedural failures Lo, Nolan et al, Heart 2009;95:410-415. Duke Master 2011
  • 6. Normal Arm Arterial System Axillary Artery Biceps Brachii Muscle Brachial Artery Brachioradialis Muscle Radial Ulnar Artery Artery Adapted from Jelev L, Cardiovasc Intervent Radiol 2008;31:1008 Duke Master 2011
  • 7. Normal Arm Angiogram Radial Artery Ulnar Artery Brachial Artery J Invasive Cardiol. 2010;22:536–540 Duke Master 2011
  • 8. Varied Radial Connections Unusual courses, no effect on passage Radial-Axillary Junction Radial-Brachial Junction Superficial Radial With High Junction Adapted from Jelev L, Cardiovasc Intervent Radiol 2008;31:1008 Duke Master 2011
  • 9. High Axillary Junction J INVASIVE CARDIOL 2010;22:536–540 Duke Master 2011
  • 10. High Radial Junction with Crossover No crossover Crossover: Potential for difficult passage & complications Adapted from Jelev L, Cardiovasc Intervent Radiol 2008;31:1008 Duke Master 2011
  • 11. Spectrum of Crossover Tight Fit Tight Turn Adapted from Jelev L, Cardiovasc Intervent Radiol 2008;31:1008 Duke Master 2011
  • 12. Angiogram: Accessory Radial Accessory or remnant radial artery Large crossover “loop” Lo, Nolan et al, Heart 2009;95:410-415. Duke Master 2011
  • 13. Radial Loops J Invasive Cardiol 2010;22:536–540 Adapted from Jelev L, Cardiovasc Intervent Radiol 2008;31:1008 Duke Master 2011
  • 14. Axillary/Subclavian Loops Icg/HMC Cath Lab Duke Master 2011
  • 15. Challenge #2: Vascular Disease Atherosclerotic Vasospastic Duke Master 2011
  • 16. Atherosclerotic Disease Calcific arteritis Arterial stenosis …but don’t confuse with spasm Maybe resolved with angioplasty …if in doubt, change access site Duke Master 2011
  • 17. Vasospastic Disease Young, anxious, female, cold Raynaud-like Syndromes Treat expectantly before symptoms Severe cases = consider femoral access Duke Master 2011
  • 18. Challenge #3: Iatrogenic Disease • Post-Trauma • Radiation • Spasm • Dissection • Perforation • Chronic injury Duke Master 2011
  • 19. Post-Brachial Cut down Icg/HMC Cath Lab Duke Master 2011
  • 20. Overcoming Challenges Expect variability, …have a plan before you start …enjoy the challenge …learn to problem solve Duke Master 2011
  • 21. Solution: Plan for Success 1. Well positioned wrist/relaxed patient 2. Micropuncture needle access 3. Prevent spasm & anticoagulate 4. Use your wire as a friend 5. If in doubt take a picture 6. Maintain central access with your wire The Radial Is Not a Small Femoral Artery Duke Master 2011
  • 22. Solution: Failure of Wire to Advance during initial access 1. Insert sheath to gain partial access – Confirm arterial access – Treat spasm 2. Load hydrophilic .035” wire in catheter & try to advance into central system 3. If successful, advance vascular sheath in place over cardiac catheter & advance coronary catheter. Duke Master 2011
  • 23. Solution: Hydrophilic Wire Fails to Advance? 1. Look under fluoroscopy at position 2. Obtain limited angiogram to define the anatomy 3. Twisting wrist may straighten forearm vessels, while a deep breath may change more proximal arteries 4. Consider smaller flexible wires, the other radial artery, the ulnar artery, or even the femoral Duke Master 2011
  • 24. Solution: Wire is your friend • Maintain wire or catheter position as central as possible (don’t retreat) • Use a standard .035” angiographic wire to hold position or help reposition catheters • Exchange over a long wire or “jet” exchange over standard length wires Do Not Retreat from Success Duke Master 2011
  • 25. Solution: Catheter “Jetting” 1. Start with catheter in ascending aorta 2. Pass .035” wire (not hydrophilic) into catheter 3. Fix wire in place & back catheter to end of wire 4. Attached 10cc syringe with fluid on catheter 5. Forcefully inject while pulling “jetting” catheter off wire until free from access sheath 6. Confirm wire still in central aortic position Hoorntje JCA. Cathet Cardiovasc Diagn 18:284, 1989. Duke Master 2011
  • 26. Returning with Next Catheter 1. Confirm wire is still in ascending aorta 2. Advance flushed catheter over wire until wire exits catheter’s hub – Ectopy indicates wire pushed into ventricle – Fluid should drip from catheter as the wire displaces flush, if not, wire may have prolapsed down descending aorta 3. Remove wire and continue procedure Duke Master 2011
  • 27. Solution: Spasm during procedure Use more pharmacology Use smaller French equipment Minimize mechanical manipulation Wipe wire, flush catheters, and “jet” with antispasmodic agents (nitrates, Ca++ blockers) Warm the arm or room Duke Master 2011
  • 28. Summary Variety is part of normal arm vasculature Makes radial “fun” Potentially a cause for failure, but… Challenges can be overcome resulting in success Expect it, have a plan, you will succeed Duke Master 2011
  • 29. Thank you Duke Master 2011