Natural Hazards: Earthquake and Volcanic Hazards + Mitigation and AdaptationKarl Ruelan
Created by: Karl Ruelan; Philippines (c) David G.
Educational Purposes Only
For Science - 11 Presentation; 8/30/16
About Natural Hazards
Specifically: Earthquake and Volcanic Hazards
It also includes: Mitigation and Adaptation to this hazards.
Powerpoint
What is Earthquake?
The minimal to rapid shaking of the ground due to the movement of rocks along fractures known as faults.
Earthquake Hazards
Surface Rupture & Physical Damage
Liquefaction
Fires
Tsunami
Landslide
Volcanic Hazards
Pyroclastic Flows and Materials
People unable to run
Bury people and agriculture
Mudflow or LAHAR
Poisonous gases
Tsunami
Volcanic Eruption
Two Types; based on magma comp.
Explosive Eruption
Non-Explosive Eruption
HAZARD MAPS
One of the government’s response to mitigate and adapt to the hazards.
Developed to indicate the places where most of the natural disasters usually occur and will most likely occur.
by the shaking itself or by the ground beneath them settling to a different level than it was before the earthquake (subsidence) or (uplift).
Subsidence is the motion of a surface (usually, the Earth's surface) as it shifts downward relative to a datum such as sea-level.
A fault is a fracture or zone of fractures between two blocks of rock. Faults allow the blocks to move relative to each other.
Philippines experience a lot of Earthquakes because it is located in the Circum-Pacific Belt, situated in the Pacific Ring of Fire
Pacific Ring of Fire is term used for VOLCANOES only.
Learning objectives:
Identify the different subsystems that make up the earth
Describe the interactions that transpire in each subsystem
Diagram the subsystems that make up the earth including the interactions that transpire in each interface.
Explain that the Earth consists of four subsystems, across whose boundaries matter and energy flow
Natural Hazards: Earthquake and Volcanic Hazards + Mitigation and AdaptationKarl Ruelan
Created by: Karl Ruelan; Philippines (c) David G.
Educational Purposes Only
For Science - 11 Presentation; 8/30/16
About Natural Hazards
Specifically: Earthquake and Volcanic Hazards
It also includes: Mitigation and Adaptation to this hazards.
Powerpoint
What is Earthquake?
The minimal to rapid shaking of the ground due to the movement of rocks along fractures known as faults.
Earthquake Hazards
Surface Rupture & Physical Damage
Liquefaction
Fires
Tsunami
Landslide
Volcanic Hazards
Pyroclastic Flows and Materials
People unable to run
Bury people and agriculture
Mudflow or LAHAR
Poisonous gases
Tsunami
Volcanic Eruption
Two Types; based on magma comp.
Explosive Eruption
Non-Explosive Eruption
HAZARD MAPS
One of the government’s response to mitigate and adapt to the hazards.
Developed to indicate the places where most of the natural disasters usually occur and will most likely occur.
by the shaking itself or by the ground beneath them settling to a different level than it was before the earthquake (subsidence) or (uplift).
Subsidence is the motion of a surface (usually, the Earth's surface) as it shifts downward relative to a datum such as sea-level.
A fault is a fracture or zone of fractures between two blocks of rock. Faults allow the blocks to move relative to each other.
Philippines experience a lot of Earthquakes because it is located in the Circum-Pacific Belt, situated in the Pacific Ring of Fire
Pacific Ring of Fire is term used for VOLCANOES only.
Learning objectives:
Identify the different subsystems that make up the earth
Describe the interactions that transpire in each subsystem
Diagram the subsystems that make up the earth including the interactions that transpire in each interface.
Explain that the Earth consists of four subsystems, across whose boundaries matter and energy flow
Earth Materials and Processes : ENDOGENIC PROCESSSimple ABbieC
Earth Materials and Processes : ENDOGENIC PROCESS
Content Standard:
The learners demonstrate an understanding of:
geologic processes that occur within the Earth and
the folding and faulting of rocks
Geologic processes that shape the planet Earth, which occurs beneath the surface and associated with Interior forces. Download this so you can see some animations and some hidden images behind some pictures.
This is a PowerPoint Presentation about Magmatism, a lesson in Earth and Life Science, First quarter for Grade 11/12 Students. This will help them understand the lesson and make them familiar with the topic.
This is a powerpoint presentation that is about one of the Senior High School Core Subject: Earth and Life Science. It is composed of the theories that explains the Earth and its Subsystems (The Four Spheres).
Earth Materials and Processes : ENDOGENIC PROCESSSimple ABbieC
Earth Materials and Processes : ENDOGENIC PROCESS
Content Standard:
The learners demonstrate an understanding of:
geologic processes that occur within the Earth and
the folding and faulting of rocks
Geologic processes that shape the planet Earth, which occurs beneath the surface and associated with Interior forces. Download this so you can see some animations and some hidden images behind some pictures.
This is a PowerPoint Presentation about Magmatism, a lesson in Earth and Life Science, First quarter for Grade 11/12 Students. This will help them understand the lesson and make them familiar with the topic.
This is a powerpoint presentation that is about one of the Senior High School Core Subject: Earth and Life Science. It is composed of the theories that explains the Earth and its Subsystems (The Four Spheres).
This presentation gives detailed information about earthquake , its types , waves , faults , especially in asian countries .A detailed case study of earthquake In NEPAL in 2015 is also covered in this with pictures . Also how it is measured and its warning system , vulnerability, deployment and future aspects has been covered .
HOPE YOU LIKE IT AND GET FULL INFORMATION!!!!!
Contents:
1. Concept of Earthquake
2. Hazards Associated to Earthquake
- Ground Shaking
- Ground Rapture
- Tsunami
- Earthquake induced landslide
3. What do to BEFORE, DURING, AFTER Earthquake
The increased availability of biomedical data, particularly in the public domain, offers the opportunity to better understand human health and to develop effective therapeutics for a wide range of unmet medical needs. However, data scientists remain stymied by the fact that data remain hard to find and to productively reuse because data and their metadata i) are wholly inaccessible, ii) are in non-standard or incompatible representations, iii) do not conform to community standards, and iv) have unclear or highly restricted terms and conditions that preclude legitimate reuse. These limitations require a rethink on data can be made machine and AI-ready - the key motivation behind the FAIR Guiding Principles. Concurrently, while recent efforts have explored the use of deep learning to fuse disparate data into predictive models for a wide range of biomedical applications, these models often fail even when the correct answer is already known, and fail to explain individual predictions in terms that data scientists can appreciate. These limitations suggest that new methods to produce practical artificial intelligence are still needed.
In this talk, I will discuss our work in (1) building an integrative knowledge infrastructure to prepare FAIR and "AI-ready" data and services along with (2) neurosymbolic AI methods to improve the quality of predictions and to generate plausible explanations. Attention is given to standards, platforms, and methods to wrangle knowledge into simple, but effective semantic and latent representations, and to make these available into standards-compliant and discoverable interfaces that can be used in model building, validation, and explanation. Our work, and those of others in the field, creates a baseline for building trustworthy and easy to deploy AI models in biomedicine.
Bio
Dr. Michel Dumontier is the Distinguished Professor of Data Science at Maastricht University, founder and executive director of the Institute of Data Science, and co-founder of the FAIR (Findable, Accessible, Interoperable and Reusable) data principles. His research explores socio-technological approaches for responsible discovery science, which includes collaborative multi-modal knowledge graphs, privacy-preserving distributed data mining, and AI methods for drug discovery and personalized medicine. His work is supported through the Dutch National Research Agenda, the Netherlands Organisation for Scientific Research, Horizon Europe, the European Open Science Cloud, the US National Institutes of Health, and a Marie-Curie Innovative Training Network. He is the editor-in-chief for the journal Data Science and is internationally recognized for his contributions in bioinformatics, biomedical informatics, and semantic technologies including ontologies and linked data.
This pdf is about the Schizophrenia.
For more details visit on YouTube; @SELF-EXPLANATORY;
https://www.youtube.com/channel/UCAiarMZDNhe1A3Rnpr_WkzA/videos
Thanks...!
Cancer cell metabolism: special Reference to Lactate PathwayAADYARAJPANDEY1
Normal Cell Metabolism:
Cellular respiration describes the series of steps that cells use to break down sugar and other chemicals to get the energy we need to function.
Energy is stored in the bonds of glucose and when glucose is broken down, much of that energy is released.
Cell utilize energy in the form of ATP.
The first step of respiration is called glycolysis. In a series of steps, glycolysis breaks glucose into two smaller molecules - a chemical called pyruvate. A small amount of ATP is formed during this process.
Most healthy cells continue the breakdown in a second process, called the Kreb's cycle. The Kreb's cycle allows cells to “burn” the pyruvates made in glycolysis to get more ATP.
The last step in the breakdown of glucose is called oxidative phosphorylation (Ox-Phos).
It takes place in specialized cell structures called mitochondria. This process produces a large amount of ATP. Importantly, cells need oxygen to complete oxidative phosphorylation.
If a cell completes only glycolysis, only 2 molecules of ATP are made per glucose. However, if the cell completes the entire respiration process (glycolysis - Kreb's - oxidative phosphorylation), about 36 molecules of ATP are created, giving it much more energy to use.
IN CANCER CELL:
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
introduction to WARBERG PHENOMENA:
WARBURG EFFECT Usually, cancer cells are highly glycolytic (glucose addiction) and take up more glucose than do normal cells from outside.
Otto Heinrich Warburg (; 8 October 1883 – 1 August 1970) In 1931 was awarded the Nobel Prize in Physiology for his "discovery of the nature and mode of action of the respiratory enzyme.
WARNBURG EFFECT : cancer cells under aerobic (well-oxygenated) conditions to metabolize glucose to lactate (aerobic glycolysis) is known as the Warburg effect. Warburg made the observation that tumor slices consume glucose and secrete lactate at a higher rate than normal tissues.
Multi-source connectivity as the driver of solar wind variability in the heli...Sérgio Sacani
The ambient solar wind that flls the heliosphere originates from multiple
sources in the solar corona and is highly structured. It is often described
as high-speed, relatively homogeneous, plasma streams from coronal
holes and slow-speed, highly variable, streams whose source regions are
under debate. A key goal of ESA/NASA’s Solar Orbiter mission is to identify
solar wind sources and understand what drives the complexity seen in the
heliosphere. By combining magnetic feld modelling and spectroscopic
techniques with high-resolution observations and measurements, we show
that the solar wind variability detected in situ by Solar Orbiter in March
2022 is driven by spatio-temporal changes in the magnetic connectivity to
multiple sources in the solar atmosphere. The magnetic feld footpoints
connected to the spacecraft moved from the boundaries of a coronal hole
to one active region (12961) and then across to another region (12957). This
is refected in the in situ measurements, which show the transition from fast
to highly Alfvénic then to slow solar wind that is disrupted by the arrival of
a coronal mass ejection. Our results describe solar wind variability at 0.5 au
but are applicable to near-Earth observatories.
Introduction:
RNA interference (RNAi) or Post-Transcriptional Gene Silencing (PTGS) is an important biological process for modulating eukaryotic gene expression.
It is highly conserved process of posttranscriptional gene silencing by which double stranded RNA (dsRNA) causes sequence-specific degradation of mRNA sequences.
dsRNA-induced gene silencing (RNAi) is reported in a wide range of eukaryotes ranging from worms, insects, mammals and plants.
This process mediates resistance to both endogenous parasitic and exogenous pathogenic nucleic acids, and regulates the expression of protein-coding genes.
What are small ncRNAs?
micro RNA (miRNA)
short interfering RNA (siRNA)
Properties of small non-coding RNA:
Involved in silencing mRNA transcripts.
Called “small” because they are usually only about 21-24 nucleotides long.
Synthesized by first cutting up longer precursor sequences (like the 61nt one that Lee discovered).
Silence an mRNA by base pairing with some sequence on the mRNA.
Discovery of siRNA?
The first small RNA:
In 1993 Rosalind Lee (Victor Ambros lab) was studying a non- coding gene in C. elegans, lin-4, that was involved in silencing of another gene, lin-14, at the appropriate time in the
development of the worm C. elegans.
Two small transcripts of lin-4 (22nt and 61nt) were found to be complementary to a sequence in the 3' UTR of lin-14.
Because lin-4 encoded no protein, she deduced that it must be these transcripts that are causing the silencing by RNA-RNA interactions.
Types of RNAi ( non coding RNA)
MiRNA
Length (23-25 nt)
Trans acting
Binds with target MRNA in mismatch
Translation inhibition
Si RNA
Length 21 nt.
Cis acting
Bind with target Mrna in perfect complementary sequence
Piwi-RNA
Length ; 25 to 36 nt.
Expressed in Germ Cells
Regulates trnasposomes activity
MECHANISM OF RNAI:
First the double-stranded RNA teams up with a protein complex named Dicer, which cuts the long RNA into short pieces.
Then another protein complex called RISC (RNA-induced silencing complex) discards one of the two RNA strands.
The RISC-docked, single-stranded RNA then pairs with the homologous mRNA and destroys it.
THE RISC COMPLEX:
RISC is large(>500kD) RNA multi- protein Binding complex which triggers MRNA degradation in response to MRNA
Unwinding of double stranded Si RNA by ATP independent Helicase
Active component of RISC is Ago proteins( ENDONUCLEASE) which cleave target MRNA.
DICER: endonuclease (RNase Family III)
Argonaute: Central Component of the RNA-Induced Silencing Complex (RISC)
One strand of the dsRNA produced by Dicer is retained in the RISC complex in association with Argonaute
ARGONAUTE PROTEIN :
1.PAZ(PIWI/Argonaute/ Zwille)- Recognition of target MRNA
2.PIWI (p-element induced wimpy Testis)- breaks Phosphodiester bond of mRNA.)RNAse H activity.
MiRNA:
The Double-stranded RNAs are naturally produced in eukaryotic cells during development, and they have a key role in regulating gene expression .
Nutraceutical market, scope and growth: Herbal drug technologyLokesh Patil
As consumer awareness of health and wellness rises, the nutraceutical market—which includes goods like functional meals, drinks, and dietary supplements that provide health advantages beyond basic nutrition—is growing significantly. As healthcare expenses rise, the population ages, and people want natural and preventative health solutions more and more, this industry is increasing quickly. Further driving market expansion are product formulation innovations and the use of cutting-edge technology for customized nutrition. With its worldwide reach, the nutraceutical industry is expected to keep growing and provide significant chances for research and investment in a number of categories, including vitamins, minerals, probiotics, and herbal supplements.
A brief information about the SCOP protein database used in bioinformatics.
The Structural Classification of Proteins (SCOP) database is a comprehensive and authoritative resource for the structural and evolutionary relationships of proteins. It provides a detailed and curated classification of protein structures, grouping them into families, superfamilies, and folds based on their structural and sequence similarities.
2. Hazard
-is a dangerous phenomenon,substance,
human activity or condition that may
cause loss of life, injury or other
health impacts, property damage, loss
of livelihood and services, social and
economic disruption, or environmental
damage as defined by the United Nations
Office for Disaster Risk Reduction
(UNDRR).
3. EARTHQUAKE
• (also known as a quake, tremor or
temblor) is the shaking of the
surface of the Earth, resulting from
the sudden release of energy in
the Earth's lithosphere that
creates seismic waves.
4. FOCUS VS EPICENTER
• Focus - where the rock breaks and
seismic waves begin; can be at
deep or shallow depths.
• Epicenter – point on the surface
directly above the focus; usually
what is used to locate the
position of an earthquake.
6. Seismic Waves
⮚ are waves of energy that travel through
the Earth's layers, and are a result
of earthquakes, volcanic eruptions, magma
movement, large landslides and large man-
made explosions that give out low-
frequency acoustic energy.
⮚ SEISMOGRAPH - is an instrument for
measuring earthquake (seismic) waves.
8. How does Volcanic
Volcanoes erupt when molten rock
called magma rises to the surface.
Magma is formed when the earth's
mantle melts.
Melting may happen where tectonic
plates are pulling apart or where one
plate is pushed down under another.
9. Types of Volcanic Eruption
★ PHREATIC OR HYDROTHERMAL -An
eruption driven by the heat in a
hydrothermal systems. Hydrothermal
eruptions pulverise surrounding
rocks and can produce ash, but do
not include magma. These are
typically very small eruptions
10.
11. Types of Volcanic Eruption
★ PHREATOMAGMATIC- An eruption
resulting from the interaction
of new magma or lava with water
and can be very explosive. The
water can be from groundwater,
hydrothermal systems, surface
runoff, a lake or the sea.
12.
13. Types of Volcanic Eruption
★ STROMBOLIAN and HAWAIIAN- These
are the least violent types of
explosive eruptions. Hawaiian
eruptions have fire fountains and
lava flows, whereas Strombolian
eruptions have explosions causing
a shower of lava fragments.
14.
15. Types of Volcanic Eruption
★ VULCANIAN ERUPTION- small to
moderate explosive eruptions,
lasting seconds to minutes. Ash
columns can be up to 20 km in
height, and lava blocks and
bombs may be ejected from the
vent.
16.
17. Types of Volcanic Eruption
★ PLINIAN and SUBPLINIAN-
Eruptions with a high rate of
magma discharge, sustained for
minutes to hours. They form a
tall, convective eruption column
of a mixture of gas and rock
particles, and can cause wide
dispersion of ash.
18.
19. Volcanic hazards directly
associated with eruption:
1. Lava flow
2. Tephra fall or ash fall and
ballistic projectiles
3. Pyroclastic density currents or
PDCs (pyroclastic flow, pyroclastic
surge, base surge)
4. Lateral blast
5. Volcanic gas
22. TYPES OF LANDSLIDE
A. Rotational – more resistant
rocks over underlying weaker
rocks;
B. Translational – occur in a
very wet weather when near
surface soil is
saturated;
23. TYPES OF LANDSLIDE
C. Block – moving mass move
downslope as a coherent mass;
D. Rock fall -single and small
rock falls from cliffs build up
to form talus;
E. Topple – occur when a cliff
is eroded by waves at its base;
24. TYPES OF LANDSLIDE
F. Debris flow – sloppy wet
mudflows to slurries of rock
debris similar to wet
concrete;
G. Debris avalanche – rushes
down the side of a volcano to
the valley floor;
25. TYPES OF LANDSLIDE
H. Earthflow – a downslope
viscous flow of fine -grained
materials saturated
I. Creep -slow downslope
movement of material under
gravity over a large
area
26. TYPES OF LANDSLIDE
J. Lateral spread – form on
gentle slopes and have a rapid
fluid-like flow.
28. TSUNAMI
-May also be caused by major
earthquakes or undersea volcanic
eruption.
-It comes from the japanese word
which literally means ―harbor
wave‖.
30. NATURAL SIGNS OF AN
APPROACHING LOCAL TSUNAMI
• A felt earthquake
• Unusual seal level change
(sudden sea water retreat or
rise)
• Rumbling sound of approaching
wave.
31. NATURAL SIGNS OF AN
APPROACHING LOCAL TSUNAMI
• A felt earthquake
• Unusual seal level change
(sudden sea water retreat or
rise)
• Rumbling sound of approaching
wave.
