"Gene Therapy" is a technique used to treat a disease or disorder by inducing the therapeutic gene into the vector, and the vector into the affected organism. So that, the therapeutic proteins expressed will vanish the affected proteins.
Gene therapy refers to the insertion of genetic material to correct a genetic defect.
In gene therapy, a "normal" gene is inserted into the genome to replace an "abnormal," disease-causing gene
The slides give general description of gene therapy and some applications, factors to be considered when applying this method, viral vectors and non viral vectors applications and finally some successses of gene therapy
In medicine, gene therapy (also called human gene transfer) is the therapeutic delivery of nucleic acid into a patient's cells as a drug to treat disease.[ The first attempt at modifying human DNA was performed in 1980 by Martin Cline, but the first successful nuclear gene transfer in humans, approved by the National Institutes of Health, was performed in May 1989.[2] The first therapeutic use of gene transfer as well as the first direct insertion of human DNA into the nuclear genome was performed by French Anderson in a trial starting in September 1990.
Gene therapy refers to the insertion of genetic material to correct a genetic defect.
In gene therapy, a "normal" gene is inserted into the genome to replace an "abnormal," disease-causing gene
The slides give general description of gene therapy and some applications, factors to be considered when applying this method, viral vectors and non viral vectors applications and finally some successses of gene therapy
In medicine, gene therapy (also called human gene transfer) is the therapeutic delivery of nucleic acid into a patient's cells as a drug to treat disease.[ The first attempt at modifying human DNA was performed in 1980 by Martin Cline, but the first successful nuclear gene transfer in humans, approved by the National Institutes of Health, was performed in May 1989.[2] The first therapeutic use of gene transfer as well as the first direct insertion of human DNA into the nuclear genome was performed by French Anderson in a trial starting in September 1990.
NUCLEIC ACID BASED THERAPEUTIC DELIVERY SYSTEM by pramesh..pptxPRAMESHPANWAR1
Name of the title: Nucleic Acid-Based Therapeutic Delivery System.
It includes information about nucleic acid, gene therapy, and its type, a method to deliver the desired DNA, i.e., vectors and their types, with proper examples and diagrams, and how these things help in delivering a nucleic acid-based therapeutic drug delivery system.
Applications, uses of 5G but also a summary of all generations of Networks we had till date.
This presentation helps to attain Konwledge, and also to get prepared for the upcoming competetive exams as well.
Exam bits related to 5G may appear in the exams under the section of Current affairs.
This Presentation helps the Studetns preparing for the CSIR-NET in Life Sciences. Not only CSIR but also the exams like DBT, GATE, ICMR, TIFR and all the other exams related to Life Sciences.
For MSc entrance exams too.
This topic deals with the Plant Metabolic process. It is under the subject Plant Physiology.
The slides shown in this PPT are very important for all the aspirants preparing for LIfe Sciences Exams like CSIR-NET, DBT-JRF, GATE, ICMR etc..
The points and MCQs depicted in this video are previously appeared in the above said exams.
This Presentation are very helpful for Lecturers to Teach and Students to Learn.
The points depicted in this presentation are very helpful for the aspirants like CSIR-NET, DBT-JRF, GATE, ICMR, TIFR etc.,
These points (some Question and Answers) are helpful for Life Sciences exams.
The tricks shown in every slide are must to remember and hence "Points to Remmeber"!!
This presentation gives the clear details on the Mammals. Information on all type of Mammals are included.
Fast and quick facts are also included. The pictures are neatly depicted by which one can understand easily.
Gestation period of Mammals are depicted in an order. Some rarely observed Mammals are shown in the initial slides.
Parents and Teachers find this presentation very helpful as this is very easy to explain their Children. Even, Civil Service Exam aspirants and other exam aspirants like Life Sciences, Groups etc., find this presentation helpful and useful for their preparation.
Quick facts 3! #StayHome and Save Lives!Bharath Raj
The facts depicted in this PPT are very useful in gaining knowledge and awareness. These are very helpful for Children to learn and even Adults also to Teach their Children or Students and ask them during leisure time.
Learning these also helps in getting prepared for competetive examinations. In Civil Services Interview, question like these are asked.
Learn well, have fun and Enjoy!!
#StayHome and help save lives #WithMe
The facts presented in this PowerPoint Presentation are interesting to learn and increases one's enthusiasm. These are very helpful for Children as well as Adults or Parents. Parents can Teach their children during leisure time holidays of lock-downtime.
In this way Parents can help their Children in gaining General Knowledge by discussing these facts!
The facts shown in this PPT are very interesting and knowledge oriented. Images are also depicted to have an easy understanding. Helpful for the Children in their School projects.
Even for Parents also. During the leisure time, you can teach these facts your Children. Imparts knowledge.
The Earth is the common Mother to all of us. She withstood many difficulties, deformations, damages and is making our Life full of Happies. As the Children, it is our responsibility to take care of Her properly and provide Her with good Health.
In this PPT, the importance of our Mother Earth and a brief History has been presented. Read it, Learn it, Enjoy it and Excel!!
She helped man people to overcome the AIDS. She is the Torch-bearer in the field of Virology. A Renowned Scientist in Life Sciences. Dr. Geeta Ramjee Madam is an Angel God for many who are being suffered with HIV-AIDS.
She introduced technical solutions to eradicate the AIDS from the society and Her research works played an amazing role in lighting up the lamp in the lives of AIDS patients instead of darkness.
The facts shown in this PPT are very interesting to learn and know. The images are also depicted for each fact so as to make the viewer understand well. The General Knowledge as well as your timee gets passed easily during this lock-down time. #StayHome #StaySafe
At present situation, the COVID-19 outbreak is disappointing every individual, every Society, every Nation and the whole World.
The necessity of Testing kits to check for the Virus among the people is need of the hour.
In this presentation, the testing kits, their types, working mechanisms, working Principle are explained in a detailed manner. Kindly go through all the slides.
The full-forms and abbreviations given in this PPT are very helpful for all the competitive examination of Life Sciences like CSIR, DBT, GATE,ICMR, NEET, AIMS etc..
The Enzymes present in our Human body are explained in this PPT. The roles of the various enzymes, their location, secreted by etc.. have been depicted. The images are also given. The digestive enzymes like Pepsin, Rennin etc.. are clearly mentioned.
The points are essential for the aspirants who are preparing for the competitive examinations (including Medical and non-medical exams).
The precautions and care to be taken to avoid the Viral infection is depicted in this PPT. Almost all the precautions are generally taught by our parents in our home like "cut your nails, wash your hands whenever you touch hair, dust off the clothes outside the house" etc...
{March 22nd is observed as the World Water Day. Ned to conserve Water, otherwise there will be no Water at least for cleaning the hands and to eliminate virus from the society. The theme for 2020 is "Water and Climate Change" i.e the link or relation between Water and Climate change. the theme for 2019 is "Leaving No One behind"}.
The points depicted in this video are so important for the aspirants of Life Sciences exams like GATE, CSIR-NET, DBT-JRF, ICAR, MSc entrance exams etc.,
These points have been asked in various above said exams previously.
Each and every slide contains very important points for the aspirants of Life Sciences examinations. Even for MSc entrance exams also these questions are very helpful in getting prepared for the exam!!
The slides depicted in this presentation carries the General knowledge bits which are very important for the competitive exam preparation.
The aspirants are advised to go through this presentation and gain knowledge. Not only for competitive exam preparation but also for children this is very helpful. Parents can ask these bits to their children randomly in random time!!
The important points on DNA Polymerase I are exclusively depicted in this Presentation. The roles and functions of DNA Pol I during the Molecular processes are discussed.
{Every year, January 24th is observed as the National Girl Child. It is the responsibility of everyone of us to bring awareness about the Girl child. Every Girl must be given proper Nutrition, proper Education, proper encouragement in the studies, Sports and Cultural activities. One is not supposed to confine the Girl to a Kitchen room. It is the right of every Girl child to get educated and become independent.
Dr. APJ Abdul Kalam Sir says, "Education is the most powerful weapon which you can use to change the world". Like that, every Girl must be educated and given a 'weapon'.}
{Disclaimer: The images have been downloaded from Google images and used in this video. I thank all the sources, references, and creators of these images. These pictures are used for EDUCATION and fair purpose only}
All the points depicted in this presentation are very important and asked in the competitive exams like CSIR, GATE and various University entrance examinations previously.
So, don't neglect these points, make a note of it and revise.
Hope you like my presentation. Thank you.
Palestine last event orientationfvgnh .pptxRaedMohamed3
An EFL lesson about the current events in Palestine. It is intended to be for intermediate students who wish to increase their listening skills through a short lesson in power point.
A Strategic Approach: GenAI in EducationPeter Windle
Artificial Intelligence (AI) technologies such as Generative AI, Image Generators and Large Language Models have had a dramatic impact on teaching, learning and assessment over the past 18 months. The most immediate threat AI posed was to Academic Integrity with Higher Education Institutes (HEIs) focusing their efforts on combating the use of GenAI in assessment. Guidelines were developed for staff and students, policies put in place too. Innovative educators have forged paths in the use of Generative AI for teaching, learning and assessments leading to pockets of transformation springing up across HEIs, often with little or no top-down guidance, support or direction.
This Gasta posits a strategic approach to integrating AI into HEIs to prepare staff, students and the curriculum for an evolving world and workplace. We will highlight the advantages of working with these technologies beyond the realm of teaching, learning and assessment by considering prompt engineering skills, industry impact, curriculum changes, and the need for staff upskilling. In contrast, not engaging strategically with Generative AI poses risks, including falling behind peers, missed opportunities and failing to ensure our graduates remain employable. The rapid evolution of AI technologies necessitates a proactive and strategic approach if we are to remain relevant.
The French Revolution, which began in 1789, was a period of radical social and political upheaval in France. It marked the decline of absolute monarchies, the rise of secular and democratic republics, and the eventual rise of Napoleon Bonaparte. This revolutionary period is crucial in understanding the transition from feudalism to modernity in Europe.
For more information, visit-www.vavaclasses.com
June 3, 2024 Anti-Semitism Letter Sent to MIT President Kornbluth and MIT Cor...Levi Shapiro
Letter from the Congress of the United States regarding Anti-Semitism sent June 3rd to MIT President Sally Kornbluth, MIT Corp Chair, Mark Gorenberg
Dear Dr. Kornbluth and Mr. Gorenberg,
The US House of Representatives is deeply concerned by ongoing and pervasive acts of antisemitic
harassment and intimidation at the Massachusetts Institute of Technology (MIT). Failing to act decisively to ensure a safe learning environment for all students would be a grave dereliction of your responsibilities as President of MIT and Chair of the MIT Corporation.
This Congress will not stand idly by and allow an environment hostile to Jewish students to persist. The House believes that your institution is in violation of Title VI of the Civil Rights Act, and the inability or
unwillingness to rectify this violation through action requires accountability.
Postsecondary education is a unique opportunity for students to learn and have their ideas and beliefs challenged. However, universities receiving hundreds of millions of federal funds annually have denied
students that opportunity and have been hijacked to become venues for the promotion of terrorism, antisemitic harassment and intimidation, unlawful encampments, and in some cases, assaults and riots.
The House of Representatives will not countenance the use of federal funds to indoctrinate students into hateful, antisemitic, anti-American supporters of terrorism. Investigations into campus antisemitism by the Committee on Education and the Workforce and the Committee on Ways and Means have been expanded into a Congress-wide probe across all relevant jurisdictions to address this national crisis. The undersigned Committees will conduct oversight into the use of federal funds at MIT and its learning environment under authorities granted to each Committee.
• The Committee on Education and the Workforce has been investigating your institution since December 7, 2023. The Committee has broad jurisdiction over postsecondary education, including its compliance with Title VI of the Civil Rights Act, campus safety concerns over disruptions to the learning environment, and the awarding of federal student aid under the Higher Education Act.
• The Committee on Oversight and Accountability is investigating the sources of funding and other support flowing to groups espousing pro-Hamas propaganda and engaged in antisemitic harassment and intimidation of students. The Committee on Oversight and Accountability is the principal oversight committee of the US House of Representatives and has broad authority to investigate “any matter” at “any time” under House Rule X.
• The Committee on Ways and Means has been investigating several universities since November 15, 2023, when the Committee held a hearing entitled From Ivory Towers to Dark Corners: Investigating the Nexus Between Antisemitism, Tax-Exempt Universities, and Terror Financing. The Committee followed the hearing with letters to those institutions on January 10, 202
Unit 8 - Information and Communication Technology (Paper I).pdfThiyagu K
This slides describes the basic concepts of ICT, basics of Email, Emerging Technology and Digital Initiatives in Education. This presentations aligns with the UGC Paper I syllabus.
2024.06.01 Introducing a competency framework for languag learning materials ...Sandy Millin
http://sandymillin.wordpress.com/iateflwebinar2024
Published classroom materials form the basis of syllabuses, drive teacher professional development, and have a potentially huge influence on learners, teachers and education systems. All teachers also create their own materials, whether a few sentences on a blackboard, a highly-structured fully-realised online course, or anything in between. Despite this, the knowledge and skills needed to create effective language learning materials are rarely part of teacher training, and are mostly learnt by trial and error.
Knowledge and skills frameworks, generally called competency frameworks, for ELT teachers, trainers and managers have existed for a few years now. However, until I created one for my MA dissertation, there wasn’t one drawing together what we need to know and do to be able to effectively produce language learning materials.
This webinar will introduce you to my framework, highlighting the key competencies I identified from my research. It will also show how anybody involved in language teaching (any language, not just English!), teacher training, managing schools or developing language learning materials can benefit from using the framework.
Introduction to AI for Nonprofits with Tapp NetworkTechSoup
Dive into the world of AI! Experts Jon Hill and Tareq Monaur will guide you through AI's role in enhancing nonprofit websites and basic marketing strategies, making it easy to understand and apply.
Embracing GenAI - A Strategic ImperativePeter Windle
Artificial Intelligence (AI) technologies such as Generative AI, Image Generators and Large Language Models have had a dramatic impact on teaching, learning and assessment over the past 18 months. The most immediate threat AI posed was to Academic Integrity with Higher Education Institutes (HEIs) focusing their efforts on combating the use of GenAI in assessment. Guidelines were developed for staff and students, policies put in place too. Innovative educators have forged paths in the use of Generative AI for teaching, learning and assessments leading to pockets of transformation springing up across HEIs, often with little or no top-down guidance, support or direction.
This Gasta posits a strategic approach to integrating AI into HEIs to prepare staff, students and the curriculum for an evolving world and workplace. We will highlight the advantages of working with these technologies beyond the realm of teaching, learning and assessment by considering prompt engineering skills, industry impact, curriculum changes, and the need for staff upskilling. In contrast, not engaging strategically with Generative AI poses risks, including falling behind peers, missed opportunities and failing to ensure our graduates remain employable. The rapid evolution of AI technologies necessitates a proactive and strategic approach if we are to remain relevant.
2. September 14, 1990 – Kum. Ashanti De
Silva(SCID).
Approaches of Gene Therapy:
Somatic cell Gene Therapy and
Germ cell Gene Therapy
4 steps are followed to develop G.T for any
specific disease
3. “Recombinant DNA Advisory
Committee(RAC)”
There are two types of gene therapy:
They are: “Ex vivo” and “In vivo” gene therapy.
Ex vivo gene therapy: (steps)
4. Vectors in Gene Therapy: (carrier particles)
a.) Viruses
b.) Human Artificial Chromosomes
c.) Bone marrow cells
6. The other virus are:
Adeno virus, Adeno – associated virus and
Herpes Simplex Virus.
AIDS virus in gene therapy:
(non-dividing cells like
brain cells effectively)
8. Examples of Ex-vivo gene therapy:
1.) SCID: (T-lymphocytes and B- lymphocytes)
Therapy for it through Ex-vivo G.T
9. 2.) Therapy for Lesch – Nyhan syndrome:
It is an inborn error in purine metabolism
HGPRT (Retroviral vector system)
3.) Therapy for Haemophilia:
• Lack of clotting factor IX
• Retroviral vector system
10. In vivo Gene therapy
Liver, muscle, skin, spleen, lung, brain and blood cells
Gene delivery by virus:
Adenoviral vector system: expresses the protein by
itself, does not integrate with the DNA of host cell.
Adeno Associated virus vector system: Diseases treated
are Hemophilia, Cystic Fibrosis(CF)
12. Gene delivery by non-viral vector
system:
Pure DNA constructs:
Simple; frequently degraded
Lipoplexes:
But the benefits are short lived.
Human Artificial Chromosomes:
Can carry one or more therapeutic genes.
13. Gene therapy for AIDS:
‘rev’ and ‘env’ genes
Antigen and antisense therapy:
Transcription using
a single stranded
nucleotide sequence.
Antisense therapy:
