Gebelik ve Trombofili - www.jinekolojivegebelik.com

TROMBOFİLİ ,[object Object],[object Object]

NORMAL FİZYOLOJİ ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

DOĞAL ANTİKOAGÜLASYON SİSTEMİ

DOĞAL ANTİKOAGÜLASYON SİSTEMİ ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

GEBELİK VE HEMOSTATİK DEĞİŞİKLİKLER ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Virchow triadı ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

GEBELİK VE HEMOSTATİK DEĞİŞİKLİKLER ,[object Object],[object Object],[object Object],[object Object],[object Object]

HEREDİTER TROMBOFİLİ ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

AKKİZ TROMBOFİLİ ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

AP C REZİSTANSI VE F- V LEİDEN MUTASYONU (FVL) ,[object Object],[object Object],[object Object],[object Object],[object Object]

AP C REZİSTANSI VE FVL MUTASYONU ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

AP C REZİSTANSI SENDROMU ,[object Object],[object Object],[object Object]

AP C REZİSTANSI VE FVL MUTASYONU ,[object Object],[object Object],[object Object]

PROTROMBİN GEN MUTASYONU (PGM) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

HİPERHOMOSİSTEİNEMİ ,[object Object],[object Object]

HİPERHOMOSİSTEİNEMİ ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

HİPERHOMOSİSTEİNEMİ ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

PROTEİN C EKSİKLİĞİ ,[object Object],[object Object],[object Object]

PROTEİN C EKSİKLİĞİ ,[object Object],[object Object],[object Object],[object Object]

PROTEİN C EKSİKLİĞİ ,[object Object],[object Object]

PROTEİN S EKSİKLİĞİ ,[object Object],[object Object],[object Object]

PROTEİN S EKSİKLİĞİ ,[object Object],[object Object],[object Object],[object Object]

ANTİTROMBİN-III EKSİKLİĞİ ,[object Object],[object Object],[object Object]

ANTİTROMBİN-III EKSİKLİĞİ ,[object Object],[object Object]

DİSFİBRİNOJENEMİ ,[object Object],[object Object],[object Object]

ANTİFOSFOLİPİD ANTİKOR SENDROMU ,[object Object],[object Object],[object Object]

ANTİFOSFOLİPİD ANTİKOR SENDROMU (APAS) ,[object Object],[object Object],[object Object],[object Object],[object Object]

APAS TANI KRİTERLERİ-1 A.Klinik Kriterler 1.Arteriel , venöz veya mikrovasküler tromboz 2.Gebelik komplikasyonları a)USG ile veya görsel olarak saptanmış fetal anomali olmadan en az 1 kez 10. gebelik haftası üzeri fetal kayıp b)Eklampsi, preeklampsi ve ciddi plasental yetersizliğe bağlı 34. gebelik haftası altında doğum c)Kromozomal ve hormonal bozukluklara bağlı olmaksızın en az 3 defa 10. gebelik haftası altında spontan düşük

APAS TANI KRİTERLERİ-2 ,[object Object],[object Object],[object Object],[object Object]

HEREDİTER TROMBOFİLİLİ GEBELERDE VTE RİSKİ

TROMBOFİLİLİ GEBELERDE VTE RİSKİ ,[object Object],[object Object],[object Object],[object Object]

TROMBOFİLİ-ERKEN GEBELİK KAYBI ,[object Object],[object Object],[object Object],[object Object]

TROMBOFİLİ-GEÇ GEBELİK KAYBI ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

TROMBOFİLİ-TEKRARLAYAN GEBELİK KAYBI

TROMBOFİLİ-KÖTÜ GEBELİK SONUÇLARI ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

TROMBOFİLİ TARAMASI ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

TROMBOFİLİ TARAMASI ,[object Object],[object Object],[object Object],[object Object]

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],UNFRAKSİYONE HEPARİN (UFH) İntrinsik Yol Ekstrinsik Yol - Heparin etki yerleri

UNFRAKSİYONE HEPARİN (UFH) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

LMWH ,[object Object],[object Object],[object Object],[object Object]

LMWH Avantajları ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

WARFARİN ,[object Object],[object Object],[object Object]

WARFARİN ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

TEDAVİ PROTOKOLLERİ Heparin UFH 25.000IU/5ml 5000 IU/ 8-12 saat DVT için 80U/kg başlangıç, 18 U/kg /saat idame LMWH Dalteparin (Fragmin) 2.500IU/mlx4mlx10 amp 10.000IU/mlx1mlx10amp 5000 U/d 100 IU/kg /12 saat 200 IU/kg /gün Enoxaparin (Clexane) 20mg/0.2mlx2enj 40mg/0.4mlx2enj 60mg/0.6mlx2enj 80mg/0.8mlx2enj 100mg/1mlx2enj 120mg/0.8mlx2enj 40 mg/d 1mg/kg /12 saat 1.5 mg/kg /gün Nadroparin (Fraxiparin) 7500 IU/0.3mlx2 enj. 10000 IU/0.4mlx2 enj. 15000 IU/0.6mlx2 enj. 38 IU /kg/d 87 IU/kg/12 saat Tinzaparin (Innohep) 3500 IU/0.35mlx10 14000 IU/0.7 ml x2 enj. 3500 IU /d 175 IU/kg/gün

TEDAVİ PROTOKOLLERİ ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

GEBELİKTE VTE RİSK FAKTÖRLERİ ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

VTE PROFİLAKSİSİ ,[object Object],[object Object],[object Object],[object Object],[object Object]

GEBELİKTE DVT TEDAVİSİ ,[object Object]

GEBELİKTE AKUT VTE TEDAVİSİ ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

ANTİKOAGÜLAN TEDAVİNİN KOMPLİKASYONLARI ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

TROMBOFİLİDE KÖTÜ GEBELİK SONUÇLARININ PROFİLAKSİSİ ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

ASPİRİN/KORTİKOSTEROİD ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

ASPİRİN ,[object Object],[object Object],[object Object],[object Object],[object Object]

ANTİKOAGULAN TEDAVİNİN GELECEĞİ ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

ANTİKOAGULAN TEDAVİNİN GELECEĞİ ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Gebelik ve Trombofili - www.jinekolojivegebelik.com

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