Expo Day: Baycrest, Lumosity, BrainBaseline & SharpBrains

2CANADIAN CENTRE FOR AGING & BRAIN HEALTH INNOVATION
PRESENTED TO
SharpBrains
November 19, 2015
Dr. Randy McIntosh
Vice President, Research

THE GLOBAL CHALLENGE
•  47.5M people with dementia now
•  1.1 billion more seniors globally by
2050; 135.5M of them will have
dementia
•  Dementia leading cause of disability
among Canadian seniors

NO CURE, BUT HOPE
•  Research
• Lifestyle strategies
• Early diagnosis/intervention
• Quality of life

OPPORTUNITY
•  Senior care and brain health markets
• Senior care projected worth $319 billion in US
by 2016
• Brain health applications, software, biometrics
projected growth to between $4 and 10 billion by
2020

BARRIERS TO INNOVATION
Lack of:
•  Focus
•  Test environment
•  Evidence
•  Supporting resources
•  Lead customer

OPPORTUNITY
Senior care and brain health markets
•  Senior care projected worth $319
billion in US by 2016
•  Brain health applications, software,
biometrics projected growth to
between $4 and 10 billion by 2020

Canadian Centre for Aging and Brain Health
Innovation (CC-ABHI)
VISION
A world in which people can age in the setting of their choice,
maintaining their cognitive, emotional and physical well-being, and
independence as long as possible
MISSION
To accelerate: development, validation, commercialization,
dissemination and adoption of innovative products, services and
best practices to support brain health and aging

FUNDING
Over next 5 years
•  $42M Government of Canada
•  $23.5M Government of Ontario
•  $33.1M Industry & Public Sector
•  $25M Donors

PROGRAM AREAS
DEVELOP
Innovative
Solutions
DISSEMINATE
Knowledge &
Best Practices
TEST
Products in
Real-World
Settings
CC-ABHI

DEVELOP
Solutions to enhance aging
•  Translate basic research into real-world
technologies, solutions and applications
•  Become a catalyst for commercialization of
technologies and solutions in this sector

TEST
Support companies and other innovators to
demonstrate, test and improve products and
processes targeting aging adults and the mental
or cognitive health of seniors
•  Healthcare organizations, governments,
physicians won’t invest without evidence.
•  CC-ABHI offers a population of elders and
expertise in testing methodologies and
generating evidence

DISSEMINATE
Disseminate solutions by providing
services to drive adoption and scalability
•  Innovations and knowledge offered to
all partners within CC-ABHI’s network
•  Experiential training, telemedicine, e-
learning modules ensure wide
adoption of validated solutions

COLLABORATION MODEL

INNOVATION PIPELINE
INNOVATION

PARTNERS TO DATE

Seniors Quality LEAP Initiative (SQLI)

Thank you
Dr. Randy McIntosh
Vice President, Research
rmcintosh@research.baycrest.org

Summit is on break.
(we will resume at 11:15am Pacific Time)

Privileged & Confidential
Lumos Labs, Inc.
Lumos Labs
SharpBrains Summit
19 November 2015
Glenn Morrison, PhD

LUMOS LABS, INC.
Our Mission
•  Create and validate training tools that aim to improve cognitive
abilities
•  Create and validate assessment tools to measure cognitive
performance
•  Advance the pace of cognitive science research
•  Expand the understanding of the human brain

LUMOS LABS, INC.
HCP Researcher Ecosystem
•  Includes university-based researchers, industry partners,
educators, clinicians, and study volunteers
•  Research areas include:
•  brain injuries and rehabilitation
•  chronic conditions
•  diseases and disorders
•  data science projects
•  education and learning
•  exercise and athletics
•  cognitive change in healthy adults

LUMOS LABS, INC.
Problem Statement for  
Brain Training Industry
➡  No clear agreement on the core elements that need to be included
in any study of CCT in order to demonstrate clear evidence of
efficacy (statistical improvement) and effectiveness (real-world
relevance)
•  ‘Stanford’ Statement
•  Statement released by The Stanford Center on
Longevity and the Berlin Max Planck Institute for
Human Development
•  Signed by 70 largely academic researchers
•  Finds that claims promoting brain games are
frequently exaggerated and at times misleading
•  Encourages continued careful research and
validation in this field
•  Open Response Letter
•  Open Letter published and signed by 127
neuroscientists, psychologists, and other experts in
the field of neural plasticity
•  Disagrees with the consensus
•  Does not agree that “there is no compelling
scientific evidence” that brain exercises “offer
consumers a scientifically grounded avenue to
reduce or reverse cognitive decline.”
•  Expressed concern that many readers of the
Stanford statement might wrongly conclude that
there is no evidence that any cognitive training
regimen can improve cognitive function

LUMOS LABS, INC.
Call to Action
•  Bring together CCT industry leaders, academics, and experts in
the field
•  Review and discuss current state of computerized cognitive
training research
•  Reach consensus on the standards for conducting adequate and
well-controlled studies to support efficacy and effectiveness
•  Publish consensus paper that those in the field can turn to for
guidance

LUMOS LABS, INC.
Open Questions for Consideration
•  What is the best control condition?
•  Active control?
•  Passive/no-contact control?
•  What is the optimal training regimen?
•  How many times/week?
•  How many weeks?
•  Requirement for booster?
•  Requirement for maintenance of eﬀect?
•  What are the best outcomes
•  Measuring cognition
•  Computerized assessments vs pencil/paper
•  Remote vs in-clinic
•  Measuring function
•  Self-reported outcomes
•  Performance based outcomes
•  Other

LUMOS LABS, INC.
How to Get Involved
•  An Industry effort and not a Lumos/Lumosity effort
•  Currently generating list of experts to reach out to and plan for an
initial meeting in early 2016
•  Small group first in an effort to identify key principles and agree on
major themes
•  Plan for larger meeting in Q1 2016
•  Interested? Contact glenn@lumoslabs.com

LUMOS LABS, INC.
Privileged & Confidential
Lumos Labs, Inc.
70 Million Bright Minds

LUMOS LABS, INC.
Summit is on break.
(we will resume at 12pm Pacific Time)

Joan Severson,
President of Digital Artefacts

Summit is on break.
(we will resume at 12:45pm Pacific Time)

Remember the opportunity…
Improve
performance Delay
decline

…but, no one shoe fits all
AGE
PERFORMANCE
25 50 75 100
PERFORMANCE
AGE

Japanese edition in 1-2 months
(Hankyu Communications)

Source: The SharpBrains Guide to Brain Fitness (second edition)

Example: Cells that fire together
wire together

Example: Don’t need to be a
car mechanic, but…

Example: Mental activity
vs. mental exercise
Source: Maguire, Woollett, & Spiers, 2006

We better start educating
users and professionals

"A stimulating, challenging resource, full of solid
information and practical tips for
improving brain health." –Kirkus Reviews
"On a personal note, I have to say I wish I had
read this awesome guide when I was much
younger.” –Scientific American
"...nice to see the new book…where all of the
relevant information is in one place." –Greater
Good Science Center at UC-Berkeley
à Amazon + Libraries

•  Getting to more readers
•  Book or another format
•  “Brain Fitness” or “Invest in your Brain”
•  Science-help vs divulgation vs self-help
•  Start or end with Jigsaw
•  Role of interviews
•  Questionnaire/ quiz?
Brainstorming

To learn more, visit sharpbrains.com

Expo Day: Baycrest, Lumosity, BrainBaseline & SharpBrains

Recommended

Recommended

More Related Content

What's hot

What's hot (20)

Similar to Expo Day: Baycrest, Lumosity, BrainBaseline & SharpBrains

Similar to Expo Day: Baycrest, Lumosity, BrainBaseline & SharpBrains (20)

More from SharpBrains

More from SharpBrains (20)

Recently uploaded

Recently uploaded (20)

Expo Day: Baycrest, Lumosity, BrainBaseline & SharpBrains