Long term benefit of microbiota transfer therapy on autism symptoms and gut m...BARRY STANLEY 2 fasd
Many studies have reported abnormal gut microbiota in individuals with Autism Spectrum Disorders (ASD), suggesting a link between gut microbiome and autism-like behaviors.
Modifying the gut microbiome is a potential route to improve gastrointestinal (GI) and behavioral symptoms in children with ASD, and fecal microbiota transplant could transform the
dysbiotic gut microbiome toward a healthy one by delivering a large number of commensal microbes from a healthy donor. We previously performed an open-label trial of Microbiota Transfer Therapy (MTT) that combined antibiotics, a bowel cleanse, a stomach-acid suppressant, and fecal microbiota transplant, and observed significant improvements in GI symptoms, autism-related symptoms, and gut microbiota. Here, we report on a follow-up with the same 18 participants two years after treatment was completed. Notably, most improvements in GI symptoms were maintained, and autism-related symptoms improved even more after the end of treatment. Important changes in gut microbiota at the end of treatment remained at follow-up, including significant increases in bacterial diversity and relative abundances of Bifidobacteria and Prevotella. Our observations demonstrate the longterm safety and efficacy of MTT as a potential therapy to treat children with ASD who have GI problems, and warrant a double-blind, placebo- controlled trial in the future.
Long term benefit of microbiota transfer therapy on autism symptoms and gut m...BARRY STANLEY 2 fasd
Many studies have reported abnormal gut microbiota in individuals with Autism Spectrum Disorders (ASD), suggesting a link between gut microbiome and autism-like behaviors.
Modifying the gut microbiome is a potential route to improve gastrointestinal (GI) and behavioral symptoms in children with ASD, and fecal microbiota transplant could transform the
dysbiotic gut microbiome toward a healthy one by delivering a large number of commensal microbes from a healthy donor. We previously performed an open-label trial of Microbiota Transfer Therapy (MTT) that combined antibiotics, a bowel cleanse, a stomach-acid suppressant, and fecal microbiota transplant, and observed significant improvements in GI symptoms, autism-related symptoms, and gut microbiota. Here, we report on a follow-up with the same 18 participants two years after treatment was completed. Notably, most improvements in GI symptoms were maintained, and autism-related symptoms improved even more after the end of treatment. Important changes in gut microbiota at the end of treatment remained at follow-up, including significant increases in bacterial diversity and relative abundances of Bifidobacteria and Prevotella. Our observations demonstrate the longterm safety and efficacy of MTT as a potential therapy to treat children with ASD who have GI problems, and warrant a double-blind, placebo- controlled trial in the future.
Dietary Strategies for Weight Loss MaintenanceMARKETDIGITALBN
Weight regain after a successful weight loss intervention is very common. Most studies
show that, on average, the weight loss attained during a weight loss intervention period is not
or is not fully maintained during follow-up. We review what is currently known about dietary
strategies for weight loss maintenance, focusing on nutrient composition by means of a systematic
review and meta-analysis of studies and discuss other potential strategies that have not been studied
so far. Twenty-one studies with 2875 participants who were overweight or obese are included in
this systematic review and meta-analysis
The Eating Behavior Questionnaire of Hendricks & Obesity Treatment FoundationEd J. Hendricks, M.D.
The EBQ is a novel behavioral psychometric scale for clinical evaluation of treatment effectiveness in treating overweight and obese patients with diet, lifestyle modification and pharmacotherapy.
Comparative Evaluation of the Effect of Doxycycline As An Adjunct to Non-Surg...QUESTJOURNAL
Background: The association between diabetes and periodontal disease has long been discussed with conflicting conclusions. Earlier studies demonstrating the relationship between diabetes and severity of periodontal disease has been equivocal. However, recent studies have clearly proven that diabetes increases the risk of periodontal disease progression. Less clear is the impact of periodontal disease on diabetes. It has been hypothesised that periodontal therapy may improve the metabolic control of diabetes. Aim: To determine the effect of doxycycline as an adjunct to non-surgical periodontal therapy in improving the metabolic control of poorly controlled type 2 diabetic subjects with chronic generalized periodontitis. Method: 30 poorly controlled type 2 diabetic subjects with chronic generalized periodontitis and receiving antidiabetic therapy were selected for the study. The subjects were randomly allotted to either of two treatment groups containing 15 subjects each: Group 1 (scaling and root planing(SRP)+ 15 days Doxycycline) or Group 2 (scaling and root planing(SRP). The Glycated haemoglobin (HbA1c) values, Gingival Index(GI), and Probing pocket depth of both the groups were assessed at baseline and after 3 months. Results: Both the treatment groups exhibited reductions in HbA1c, G I and Probing pocket depth compared to baseline over time. The amount of reduction in the glycated haemoglobin and gingival parameters was higher in Group I compared to group 2 after 3 months. Conclusion: Both treatments improved glycemic control in patients with type 2 diabetes; however, the reduction in HbA1c values reached statistical significance only in the group receiving doxycycline as an adjunct to scaling and root planing.
The IOSR Journal of Pharmacy (IOSRPHR) is an open access online & offline peer reviewed international journal, which publishes innovative research papers, reviews, mini-reviews, short communications and notes dealing with Pharmaceutical Sciences( Pharmaceutical Technology, Pharmaceutics, Biopharmaceutics, Pharmacokinetics, Pharmaceutical/Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmacognosy & Phytochemistry, Pharmacology, Pharmaceutical Analysis, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics and Biotechnology of Pharmaceutical Interest........more details on Aim & Scope).
All manuscripts are subject to rapid peer review. Those of high quality (not previously published and not under consideration for publication in another journal) will be published without delay.
PEPTIC (Holden Young - Roseman University College of Pharmacy)HoldenYoung3
PEPTIC (Holden Young - Roseman University College of Pharmacy)
Effect of stress ulcer prophylaxis with proton pump inhibitors vs histamine-2 receptor blockers on in-hospital
mortality among ICU patients receiving invasive mechanical ventilation (PEPTIC).
JAMA . 2020; 323(7):616-626
Dietary Strategies for Weight Loss MaintenanceMARKETDIGITALBN
Weight regain after a successful weight loss intervention is very common. Most studies
show that, on average, the weight loss attained during a weight loss intervention period is not
or is not fully maintained during follow-up. We review what is currently known about dietary
strategies for weight loss maintenance, focusing on nutrient composition by means of a systematic
review and meta-analysis of studies and discuss other potential strategies that have not been studied
so far. Twenty-one studies with 2875 participants who were overweight or obese are included in
this systematic review and meta-analysis
The Eating Behavior Questionnaire of Hendricks & Obesity Treatment FoundationEd J. Hendricks, M.D.
The EBQ is a novel behavioral psychometric scale for clinical evaluation of treatment effectiveness in treating overweight and obese patients with diet, lifestyle modification and pharmacotherapy.
Comparative Evaluation of the Effect of Doxycycline As An Adjunct to Non-Surg...QUESTJOURNAL
Background: The association between diabetes and periodontal disease has long been discussed with conflicting conclusions. Earlier studies demonstrating the relationship between diabetes and severity of periodontal disease has been equivocal. However, recent studies have clearly proven that diabetes increases the risk of periodontal disease progression. Less clear is the impact of periodontal disease on diabetes. It has been hypothesised that periodontal therapy may improve the metabolic control of diabetes. Aim: To determine the effect of doxycycline as an adjunct to non-surgical periodontal therapy in improving the metabolic control of poorly controlled type 2 diabetic subjects with chronic generalized periodontitis. Method: 30 poorly controlled type 2 diabetic subjects with chronic generalized periodontitis and receiving antidiabetic therapy were selected for the study. The subjects were randomly allotted to either of two treatment groups containing 15 subjects each: Group 1 (scaling and root planing(SRP)+ 15 days Doxycycline) or Group 2 (scaling and root planing(SRP). The Glycated haemoglobin (HbA1c) values, Gingival Index(GI), and Probing pocket depth of both the groups were assessed at baseline and after 3 months. Results: Both the treatment groups exhibited reductions in HbA1c, G I and Probing pocket depth compared to baseline over time. The amount of reduction in the glycated haemoglobin and gingival parameters was higher in Group I compared to group 2 after 3 months. Conclusion: Both treatments improved glycemic control in patients with type 2 diabetes; however, the reduction in HbA1c values reached statistical significance only in the group receiving doxycycline as an adjunct to scaling and root planing.
The IOSR Journal of Pharmacy (IOSRPHR) is an open access online & offline peer reviewed international journal, which publishes innovative research papers, reviews, mini-reviews, short communications and notes dealing with Pharmaceutical Sciences( Pharmaceutical Technology, Pharmaceutics, Biopharmaceutics, Pharmacokinetics, Pharmaceutical/Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmacognosy & Phytochemistry, Pharmacology, Pharmaceutical Analysis, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics and Biotechnology of Pharmaceutical Interest........more details on Aim & Scope).
All manuscripts are subject to rapid peer review. Those of high quality (not previously published and not under consideration for publication in another journal) will be published without delay.
PEPTIC (Holden Young - Roseman University College of Pharmacy)HoldenYoung3
PEPTIC (Holden Young - Roseman University College of Pharmacy)
Effect of stress ulcer prophylaxis with proton pump inhibitors vs histamine-2 receptor blockers on in-hospital
mortality among ICU patients receiving invasive mechanical ventilation (PEPTIC).
JAMA . 2020; 323(7):616-626
Alicia Wong1
, Wan Chien Han1
, Elsie Low1
,
Chai Xiang Goh1
,
Siew Li Ng1
,
Lee Kuan Kwan1
Abstract: Diabetes-specific formulas have shown to be effective at improving glucose control with additional
nutritional benefits. Furthermore, diabetes-specific formulas are commonly used for diabetic patients with
insufficient oral intake. However, not much diabetes-specific formulas in the market shows the GI of these
formulas, which is clinically useful on glycemic control in patients with diabetes. The aim of this study was to
assess the GI of a newly developed diabetes-specific formula, Contro eazy NOW. The open labelled, single center
study involved 11 individuals from a pool of 18 healthy subjects. After an overnight fast, volunteers were given
Contro eazy NOW containing 50g of carbohydrate or the reference drink (glucolin) on different occasions in
random order. Postprandial blood glucose levels were measured in finger pricked capillary blood for two hours
after intake of the beverages and positive incremental area under the curve (AUC) was calculated for both Contro
eazy NOW and reference drink. The GI of Contro eazy NOW was determined by dividing AUC (Contro eazy
NOW) by the AUC (reference drink). The results show that the diabetes-specific formula has the GI of 38.4, which
is categorized as low GI. Therefore, Contro eazy NOW with low GI can be the preferred option for nutritional
management of diabetic patients in need of nutritional support.
Keywords: diabetes-specific formula, diabetes, low glycemic index, medical nutrition therapy.
Fast impact of lifestyle and functional interventions on adults affected by n...Metagenics Academy
Results of a observational study presented at the Australasian Congress of Lifestyle Medicine - Nov 4th 2016 . Autors L. Maselli, A. Saggioro, M.Salamone) Patients used MetaClear a formulation of vitamins, minerals and plant extracts that supports liver and detox function.
Increase your Understanding of the Pathogenesis of Gluten Spectrum DisordersCell Science Systems
Recently, researchers at Harvard University, Alessio Fasano et. al., and the National Institutes of Health (laboratories of immunology and cellular and molecular biology), reported real-time microscopic observations of gluten-induced neutrophil activation.
According to authors, " To what extent neutrophil function adds to, or protects against, gluten intolerance is currently under vigorous investigation."
This presentation will shed light on this question. It will also review the Fasano study and examine the role of neutrophil function in multiple disease conditions, as well as explore how neutrophil function may also play a dual role in protecting the body from the untoward effects of dietary and environmental agents.
Alicia Wong1
, Wan Chien Han1
, Elsie Low1
,Chai Xiang Goh1
, Siew Li Ng1
,
Lee Kuan Kwan1
1Alpro Academy, Lot 45880, Jalan Techvalley 3/2, Sendayan Techvally, 71950 Bandar Sri Sendayan, Negeri Sembilan,
Malaysia.
Abstract: Glycemic index (GI) describes the blood glucose response after consumption of a carbohydrate
containing test food relative to a carbohydrate containing reference food, typically glucose or white bread. GI was
originally designed for people with diabetes as a guide to food selection, and advice being given to select foods with
a low GI. Nonetheless low GI food should not be limited to diabetes patients but healthy individuals too as more
recent recommendations on the potential of low GI diets to reduce the risk of chronic diseases and to treat other
metabolic syndromes. This study aims to evaluate the GI of 2 oral nutritional supplements, Metabolic Recovery
and Metabolic Relievve in healthy adults. Fasted subjects consumed one of the 2 oral nutritional supplements at
each visit, with a two day wash out period between visits. Every subject received both oral nutritional supplements
and blood glucose at 0, 15, 30, 45, 60, 90 and 120 mins were measured after the consumption of oral nutritional
supplements which all containing 50g carbohydrates per serving. The trapezium method was used to compute the
area under the curve for blood glucose and GI of both oral nutritional supplements were determined with
reference to glucolin. The results show that both oral nutritional supplements has low GI, with Metabolic Recovery
having the GI of 46.7 ± 16.4 and Metabolic Relievve with GI of 45.2 ± 16.4. Therefore, both Metabolic Recovery
and Metabolic Relievve can be the preferred option for nutritional management of diabetic patients and healthy
individuals in need of nutritional support.
Keywords: Oral nutritional supplements, glycemic index, blood sugar level, diabetes, meal replacement.
Background: One of the commonest complications of poorly controlled Type 2 diabetes mellitus (T2DM) is Diabetic nephropathy (DN), which occurs in 30-40% of DM cases. It is important to identify the high-risk group who are likely to develop DN with the modifiable and non-modifiable risk factors. This study had the objectives to estimate and correlate the levels of the urine albumin creatinine ratio (UACR) with age, anthropometric measures, glycaemic control markers, lipids, and renal function. To estimate each variable as independent and multivariate risk factors.
Materials and Methods: It was an observational and cross-sectional study conducted in a tertiary care center in Eastern India. Totally, 221 consecutive ambulatory T2DM subjects were recruited after obtaining their written consent.
Results: The diabetics were classified as having diabetic nephropathy by the urine albumin creatinine ratio (ACR) of >30 mg/gm. 53.4% of our study group had DN. There was a significant risk associated with PPBS with p=0.043 (<0.05), serum creatinine with p=0.032 (<0.05), and urine albumin with p=0.0001 (<0.001). In the multivariate regression analysis of all these variables, there was a highly significant likelihood ratio for predicting DN with p=0.0001 (<0.001) with a predictive value of 74.5% in females and 75% in males.
Conclusion: The additive factors contributed by the risk factors in the prediction of DN will benefit the DM in the prevention of DN.
Keywords: diabetic nephropathy, risk factors, diabetic kidney disease, Asian Indian
Alcat Workshop - Applicazione del test d’intolleranze - Milano, 26 gennaio 2013
Intervento del DR. Alessandro Scorba - Medico Chirurgo, Esperto in Intolleranze Alimentari.
Applicazione del Test di Nutrigenomica come strumento di ausilio Clinico e Diagnostico:
Sindrome Metabolica
Predisposizione al Diabete di Tipo 2
Intolleranza al Lattosio e Glutine
Gluten Sensitivity
Venerdì 25 gennaio 2013, a Milano, presso il ristorante Tondo - via Stephenson 55, si terrà il “Bello del senza Glutine”, una cena senza glutine organizzata dall’Associazione Nonna Paperina in collaborazione con Alcat Test Italia.
Si potrà scegliere tra due differenti tipologie di menù senza glutine: il Menù Pizza o il Menù Carne.
Durante la serata, grazie alla presenza del Prof. Giuseppe Di Fede e dei nutrizionisti di ALCAT Test Italia, che risponderanno alle domande dei partecipanti, sarà possibile approfondire la conoscenza delle intolleranze alimentari e capire in che modo adottare sane abitudini alimentari escludendo gli allergeni responsabili.
All’incontro sarà presente anche il rinomato pastrychef Francesco Favorito - impegnato da oltre 12 anni nel campo delle intolleranze alimentari - che presenterà i suoi libri.
Il costo è di Euro 25 a persona. Incluso nel prezzo l’aperitivo bio offerto da Azienda Agricola Milanesi.
Per Informazioni e prenotazioni:
Tel. 342 0136502 • mail: info@ilmondodelleintolleranze.it
Oltre alla dermatite da contatto, classica manifestazione di allergia conclamata, esistono forme cliniche, attribuibili a fenomeni d’intolleranza, che si manifestano con un corredo sintomatologico più sfumato, e a volte diverso da quello della classica allergia. In questo caso, l’alimentazione assume un ruolo decisivo. Numerosi sono, infatti, i cibi contenenti discrete quantità di nichel: cacao, legumi, funghi, cipolla, pomodoro. Bisogna, inoltre, tenere in considerazione che il nichel solfato è ampiamente utilizzato come additivo negli alimenti, in particolare nei grassi idrogenati.
Con la sindrome metabolica aumenta il rischio di sviluppare una malattia oncologica. È quanto emerge dal III Congresso Internazionale ARTOI, tenutosi a Roma il 2-3 dicembre 2011.
I Radicali Liberi sono prodotti di scarto che si formano naturalmente all’interno delle cellule del nostro corpo quando l’ossigeno è utilizzato nei processi metabolici per produrre energia (ossidazione). Se sono in quantità minima, aiutano il Sistema Immunitario nell’eliminazione dei germi mediante perossidazione lipidica (denaturazione membrane batteriche); mediante un’azione mutagena sul DNA; mediante ossidazione dei Citocromi (arresto respirazione mitocondriale). Se non sono prontamente neutralizzati dai sistemi Antiossidanti, danneggiano i tessuti e le cellule circostanti interrompendo i processi cellulari vitali.
Le diete del futuro saranno messe a punto a partire dalla mappatura del Dna .
Dimenticate le calorie. La nuova chiave di volta per il benessere e la salute si chiama nutrigenomica che permetterà, attraverso lo studio del fenotipo, di elaborare il corretto regime alimentare
La farmacogenomica è una scienza emergente in grado di evidenziare come le nuove conoscenze sul DNA umano e sui suoi prodotti (gli RNA e le Proteine) possano essere utilizzati nella scoperta e nello sviluppo di nuovi farmaci.
Le Intolleranze Alimentari provocano una reazione infiammatoria cronica, caratterizzata dalla produzione di sostanze che acidificano i tessuti ed il sangue, rallentando il metabolismo e favorendo l’aumento di peso. Inoltre le Intolleranze ostacolano l’attività dell’Insulina, provocando una sensazione di fame perenne.
Come identificare le patologie legate agli
alimenti e quali opportunità di cura esistono?
Attraverso gli esami del sangue, il test ALCAT e nuove discipline come la nutraceutica
La bella stagione con le vacanze estive e i week-end fuori porta potrebbe essere una occasione favorevole per combinare il tentativo di migliorare il quadro dell’intolleranza associando la correzione dell’alimentazione con uno stile di vita più adeguato.
More from Imgep - Istituto di Medicina Genetica Preventiva (20)
263778731218 Abortion Clinic /Pills In Harare ,sisternakatoto
263778731218 Abortion Clinic /Pills In Harare ,ABORTION WOMEN’S CLINIC +27730423979 IN women clinic we believe that every woman should be able to make choices in her pregnancy. Our job is to provide compassionate care, safety,affordable and confidential services. That’s why we have won the trust from all generations of women all over the world. we use non surgical method(Abortion pills) to terminate…Dr.LISA +27730423979women Clinic is committed to providing the highest quality of obstetrical and gynecological care to women of all ages. Our dedicated staff aim to treat each patient and her health concerns with compassion and respect.Our dedicated group ABORTION WOMEN’S CLINIC +27730423979 IN women clinic we believe that every woman should be able to make choices in her pregnancy. Our job is to provide compassionate care, safety,affordable and confidential services. That’s why we have won the trust from all generations of women all over the world. we use non surgical method(Abortion pills) to terminate…Dr.LISA +27730423979women Clinic is committed to providing the highest quality of obstetrical and gynecological care to women of all ages. Our dedicated staff aim to treat each patient and her health concerns with compassion and respect.Our dedicated group of receptionists, nurses, and physicians have worked together as a teamof receptionists, nurses, and physicians have worked together as a team wwww.lisywomensclinic.co.za/
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
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Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
Are There Any Natural Remedies To Treat Syphilis.pdf
Evaluation of alcat test results in the non ig e mediated pathology of the skin
1. Evaluation of ALCAT Test results in the non IgE-mediated pathology of the skin
De Amici M.°, Berardi L.^, Castello M.^, Mantegna G.°, Giunta V.°, Ronzi G.^, Vignini M.^
^ Dermatology Clinic- University of Pavia- Foundation IRCCS Policlinic San Matteo; Pavia, Italy
° Hospital Pediatric Clinic – Foundation IRCCS Policlinic San Matteo; Pavia, Italy
Background
Specific foods can induce cutaneous reactions, including allergies that involve an abnormal
immunologic reaction to food proteins or food intolerance which is not immunological in nature.
The aim of this study was to evaluate whether food intolerance is associated with cutaneous
reactions, and evaluate the diagnostic value of the ALCAT test in food intolerance.
Methods
35 patients (22 females, 13 males, median age 41.5 yrs) affected by cutaneous reactions, such as
urticaria, angioedema, itching and dermatitis consequent to food ingestion were tested by ALCAT.
Patients also answered a survey regarding a tailored (diet based on ALCAT results) 2 month
elimination diet. Clinical evaluation was also performed considering the symptom score before and
after the diet (0-10), everyday conditioning (0-10), dietary changes (0-10), improvement symptoms
after diet (1=nothing; 2=mild; 3=very important).
The ALCAT test electronically measures volumetric shifts in blood cells following incubation with
food antigens. The degree of reactivity was determined by comparing a baseline distribution curve
against the distribution curve generated by the analysis of each test agent/blood sample and
calculating the absolute differences between curves and the standard deviation (SD). Any reactivity
under 2 SD was considered non-reactive and these foods were allowed in diet.
Quantitative parameters were reported as medians (md) and 1st-3rd quartiles (IQR). The Wilcoxon
and the Kruskal-Wallis test were performed. A p-value≤0.05 was considered statistically significant
Results
66% of patients exhibited a very important improvement in symptoms, 31% mild improvement and
3% no change. The symptom score before diet changed among improvements symptoms score, but
the difference was not significant (p=0.07). Moreover, dietary changes significantly changed
(p=0.001) among improvements symptoms score; in particular, higher values of dietary changes
were associated with large improvements. Finally, difference between symptom score before (md:7;
IQR:6-8) and after diet (md:4; IQR:3-6) was significant (p=0.0001).
Conclusion
2. The study provides evidence that an elimination diet based on ALCAT test results improves
symptoms in 66% of patients. Mild improvements should be considered the result of patient
subjectivity (placebo effect) and the benefits resulting from proper nutrition.
In conclusion, we demonstrate the beneficial role of ALCAT test.