How to prevent occurrence of severe ovarian hyperstimulation in IVF. Is there a way ? this talk will present a pilot randomised study that may shed the light on this
platelet rich plasma is being used in infertility management extensively without sound evidence of its value. In this talk, we will discuss the real impact of using PRP in IVF
we are in need to describe investigations for our patients but over prescription of these investigations especially if unnecessary could be considered abuse
How to prevent occurrence of severe ovarian hyperstimulation in IVF. Is there a way ? this talk will present a pilot randomised study that may shed the light on this
platelet rich plasma is being used in infertility management extensively without sound evidence of its value. In this talk, we will discuss the real impact of using PRP in IVF
we are in need to describe investigations for our patients but over prescription of these investigations especially if unnecessary could be considered abuse
How to choose between drugs: efficacy / safety and cost effectiveness. In IVF, we have GnRHagonist and antagonists: how to choose based on best available evidence. This talk may help to answer this question
Anti-Müllerian Hormone (AMH) is critical for physiologic involution of the Mullerian ducts during sexual differentiation in the male foetus.
In women,AMH is a product of the small antral follicles in the ovaries and serves to function as an autocrine and paracrine regulator of follicular maturation
Invited Lecture delivered by Dr Sujoy Dasgupta in National Youth Conference, held at Patna in August 2019. This session was sponsored by Bharat Serum and Vaccines
Free Information Session 5th September 2012: Recent Breakthroughs in IVFFertility SA
Dr Louise Hull spoke about new technologies which are improving outcomes and making fertility treatment a more straightforward process. She covered how they fit into our current treatment plans, the reasons for developing them and the evidence regarding the benefits.
Dr Hull has worked in fertility services since she graduated as a doctor 15 years ago. She became Obstetrician and Gynaecologist (FRANZCOG) after gaining clinical experience in New Zealand and Cambridge and Somerset in the UK. Louise has a strong interest in reproductive medicine and has worked in IVF units in New Zealand, England and Australia, including Bourn Hall, the fertility centre where the first IVF baby was born. For more information about Dr Hull, please follow this link: http://www.fertilitysa.com.au/dr-m.-louise-hull-specialist.html
How to choose between drugs: efficacy / safety and cost effectiveness. In IVF, we have GnRHagonist and antagonists: how to choose based on best available evidence. This talk may help to answer this question
Anti-Müllerian Hormone (AMH) is critical for physiologic involution of the Mullerian ducts during sexual differentiation in the male foetus.
In women,AMH is a product of the small antral follicles in the ovaries and serves to function as an autocrine and paracrine regulator of follicular maturation
Invited Lecture delivered by Dr Sujoy Dasgupta in National Youth Conference, held at Patna in August 2019. This session was sponsored by Bharat Serum and Vaccines
Free Information Session 5th September 2012: Recent Breakthroughs in IVFFertility SA
Dr Louise Hull spoke about new technologies which are improving outcomes and making fertility treatment a more straightforward process. She covered how they fit into our current treatment plans, the reasons for developing them and the evidence regarding the benefits.
Dr Hull has worked in fertility services since she graduated as a doctor 15 years ago. She became Obstetrician and Gynaecologist (FRANZCOG) after gaining clinical experience in New Zealand and Cambridge and Somerset in the UK. Louise has a strong interest in reproductive medicine and has worked in IVF units in New Zealand, England and Australia, including Bourn Hall, the fertility centre where the first IVF baby was born. For more information about Dr Hull, please follow this link: http://www.fertilitysa.com.au/dr-m.-louise-hull-specialist.html
The Assisted Reproductive Techniques - ART (IVF, IUI, ZIFT, GIFT, ICSI etc.)Muhammad Anas Shamsi
Assisted reproductive technology (ART) is used to treat infertility. It includes fertility treatments that handle both a woman's egg and a man's sperm. It works by removing eggs from a woman's body. The eggs are then mixed with sperm to make embryos. The embryos are then put back in the woman's body. In vitro fertilization (IVF) is the most common and effective type of ART.
IVF is the process of fertilization by extracting eggs, retrieving a sperm sample, and then manually combining an egg and sperm in a laboratory dish. The embryo(s) is then transferred to the uterus. Other forms of ART include gamete intrafallopian transfer (GIFT) and zygote intrafallopian transfer (ZIFT).
In vitro fertilization (IVF) is the process of fertilizing an egg with sperm outside the body in a
laboratory setting and then implanting and developing the embryo in the woman's uterus, where it
will implant and grow into a baby.
Indivisualization of Ovulation Induction - Dr Dhorepatil BharatiBharati Dhorepatil
IVF started to develop fast with the aim of maximizing pregnancy rates per cycle
Higher number of oocytes and thus more embryos
Use of unphysiological high doses of gonadotropins
Time consuming protocols
Higher costs
Patient discomfort
Higher risk of OHSS
Very high risk of multiple gestation
Since the birth of Louise Brown, the first baby born through in vitro fertilization, in 1978, assisted reproductive technology has advanced significantly. The success rate of in vitro fertilization (IVF) has risen dramatically over the last four decades as a result of developments in incubation methods, micromanipulation technology, and a general understanding of assisted reproduction.
Individualized ovarian stimulation protocols in IVF (1).pptxRaju Nair
Explaining the best protocol for ivf stimulation. How we can optimize the stimulation regimen to get adequate response and there by healthy baby is a challenge
we need to update our knowledge regarding management of endometriosis.
Which is better: medications or surgery? let's see what can this talk tell us about
what is the efficacy of Dienogest for management of endometriosis? let's see what research can tell us
Is it better that other modalities of management?
IVF will remain the solution for infertile couples. But its future will dramatically be directed to fertile couples !!!! This talk will discuss these issues
How to deal with covid cases who want to get pregnant and those who already are pregnant : A dllema
Vaccine or No vaccine : we will answer this in this talk
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
The Gram stain is a fundamental technique in microbiology used to classify bacteria based on their cell wall structure. It provides a quick and simple method to distinguish between Gram-positive and Gram-negative bacteria, which have different susceptibilities to antibiotics
- Video recording of this lecture in English language: https://youtu.be/kqbnxVAZs-0
- Video recording of this lecture in Arabic language: https://youtu.be/SINlygW1Mpc
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Basavarajeeyam is a Sreshta Sangraha grantha (Compiled book ), written by Neelkanta kotturu Basavaraja Virachita. It contains 25 Prakaranas, First 24 Chapters related to Rogas& 25th to Rasadravyas.
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
4. What is clear?
• Is infertility a disease?
• Can ART be applied?
• Is donor gamete forbidden?
• PGD
• Postmenopausal pregnancy
• Surrogate mother
5. Unclear
• cryopreservation
• sex selection?
• Mitochondria transfer
• Is stem cells a valid option?
• SER
• cloning
• Embryo research
• Sporadic models
6. Is infertility a disease?
• Many countries allover the world including USA consider fertility a
complimentary to life (welfare)
• Most insurance companies refuse infertility treatment
7. This has been solved
• the World Health Organization (WHO)
acknowledged that infertility should be
considered a disease to all intents and purposes,
as it diminishes the health and wellbeing of the
individuals who suffers from it.
• Accordingly it is a human right to get infertility
treatment
8. Is donor insemination or oocytes allowed?
• As Islam enjoys the purity of genes and heredity, It deems that each
child should relate to a known father and mother.
• A third party is not acceptable whether he or she is providing a
sperm, an egg, an embryo or a uterus (Serour and Omran, 1992).
9. Is assisted reproduction valid?
• A November 2000 workshop organized by the International Islamic
Center for Population Studies and Research, Al-Azhar University,
Cairo, considered use of assisted reproduction technologies (ART) in
the Islamic world.
10. 10
PGD
• It is accepted to use preimplantation genetic
diagnosis to prevent hereditary diseases
• sex selection has been permitted for family
balancing.
• Certain precautions and restriction were
suggested to be applied to avoid its abuse
11. What about Stem cells: In POF?
• AFSCs were transplanted into the ovaries of mice with POF six weeks
post induction using chemotherapeutic drugs.
• the transplanted AFSCs did not differentiate into germ line cells in
vivo.
12. Stem cells types References
Stem cells and
germ cells
markers
Chemotherapy
Morphologically
of ovary after
stem cells
transplanted
Hormone or cytokines profile
changes
Tracking of stem cells
Bone marrow
transplantation
Lee et al.43 / / /
BMP15, FMR1, FSHR, INHA, AMH,
NOBOX, FOXO3, EIF2B, FIGLA and
GDF9
Reactivate host oogenesis; not
generate oocytes
CD44 +/CD105 +
human amniotic
fluid
mesenchymal
stem cells
Liu et al.73
CD29, CD44,
CD73, CD90,
CD105 and CD166
Intraperitoneal
injection of
cyclophosphamide
/ / /
Adipose-derived
stem cells
Sun et al.63 /
Intraperitoneal
injection of
cyclophosphamide
Follicle number ,
ovulation number
and apoptotic
GCs¯
HGF , VEGF, PGF and TGF-β
Not participate in follicle
regeneration
Umbilical cord
mesenchymal
stem cells
Wang et al.64
CD29, CD44,CD90
and CD105
Intraperitoneal
injection of
cyclophosphamide
Apoptosis of GC¯,
number of
folliclesand oocyte
containing follicles
E2 Not develop into follicles
Human amniotic
fluid cells
Lai et al.72
Intraperitoneal
injection of
cyclophosphamide
and busulphan
Oocytes at all
stages
AMH and FSHR
Differentiated into GCs; not germ
cell
13. Summary of results
• No evidence of differentiation into oocytes
• But risk of developing GC tumour is potential (Botman , 2014)
• So till now, use of stem cells for POF in human is not valid
14.
15.
16. What is unclear?
• Cryo preservation !!!!!!
• Models of individual practice?
17. 17
Cloning
• human reproductive cloning is condemned,
but cloning human embryos for stem cell
research is considered acceptable Serour &
Dickens , 2001
• The majority of Muslim jurists distinguish
between reproductive and therapeutic cloning
(Larijani , Zahedi F.,2004)
18. 18
Multifetal pregnancy reduction
• According to Islamic view, MFPR is only allowed
if the prospect of carrying the pregnancy to
viability is very small.
• It is also allowed if the life or health of the
mother is in jeopardy.
• Every attempt should be made to prevent the
incidence of multiple pregnancy, especially
high-order multiple pregnancy.
19. 19
• When MFPR is performed, it is not performed with
the objective of inducing abortion. MFPR is
performed with the objective of increasing the
chances of continuation of the pregnancy and the
chances of survival of the remaining fetus or
fetuses (al-Shazil, 1995).
21. • ART allow postmenopausal women to become
pregnant. The physiological process occuring
with pregnancy no doubt task and exhaust the
health reserves of the woman.
Pregnancy in the postmenopause, involves egg
donation, accordingly, using donated eggs is
ethically unacceptable in the Muslim World
22. Pregnancy in the postmenopausal using couple’s
frozen embryos is associated with increased
maternal risks and need further evaluation.
23. 23
Embryo research
• According to religious recommendations,
research would occur only on spare embryos
created as by-products of IVF treatment for
infertility.
• However, the wide use of cryopreservation of
extra embryos has limited the number of
embryos donated for research
24. 24
Embryo Research
• Cryopreserved pre-embryos may be used for
research purposes with the free and informed
consent of the couple.
• These pre-embryos are not to be transferred
to the uterus of the wife or that of any other
woman
25. Mitochondrial transfer ?
• use of mitochondrial donation in carefully selected women to
improve their chances of having children free of inherited
mitochondrial diseases