2. What is Erythema Nodosum?
• A painful inflammatory
disorder in which crops of
tender nodules occur in
response to antigenic stimuli.
• Usually it is limited to the
extensor aspects of the lower
legs.
4. Clinical presentation:
1- At the beginning:
* red tender nodules ,
* poorly Defined border,
* vary from 2-6 cm.
2- During the first week:
lesions become tense, hard, and painful
3- During the second week:
they may become fluctuant, as in an abscess, but do not suppurate
or ulcerate.
4- Aching legs and swelling ankles may persist for weeks.
5. Investigations:
• 1- Throat culture for streptococcus
• 2- Chest X-ray sarcoidosis and TB
• 3- Skin biopsy for difficult cases
