This document provides guidance on grossing techniques for pathology specimens. It discusses proper specimen identification, labeling, collection, fixation and storage. The ideal properties of fixatives are outlined, including preventing autolysis and bacterial growth while maintaining tissue morphology. Common fixatives like neutral buffered formalin are described along with their advantages and limitations. The key steps of gross examination involve describing the location, size, shape and abnormalities seen in specimens before selecting portions for microscopic analysis.