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NATIONAL GUIDELINES AND
PROTOCOLS IN CRITICAL CARE
NUTRITION PRACTICE
DR ANKIT GAJJAR
MD, IDCCM, IFCCM, EDIC
CONSULTANT INTENSIVIST
“Our food should be our medicine and our
medicine should be our food”
- Hippocrates
INTRODUCTION
• WHY?
• WHEN?
• HOW MUCH?
• ROUTE?
• CONTRAINDICATIONS?
• COMPLICATIONS?
• MONITORING?
• DISEASE SPECIFIC
WHY
• Catabolic stress state
• SIRS
• Complications
– Infectious
– Morbidity
– Multi-organ failure
• Adequate nutrition
– Attenuate metabolic response to stress
– Favorably modulate immune responses
– Decrease in length of hospital stay, morbidity rate
and improvement in patient outcomes
Nutrition Screening and Assessment
• Indirect calorimetry – best method
• Nutrition status of Indian malnourished patients
can be assessed by SGA.
• Initial monitoring of nutrition intervention must
be done on daily basis and nutrition plans should
be modified accordingly.
• It is imperative that nutritional assessment is
done by well-qualified and trained nutritionists,
dedicated to the ICU.
• Facilitation of nutrition assessment will require
good coordination between intensivist and
nutritionist.
WHEN
• As early as possible
• At least in first 48 hours
• HD instability
– Start after shock resuscitation
• Tube feed if cant achieve 50% of requirment in 72
hours
• 100% in 7 days
• Parenteral nutrition only if enteral nutrition
cannot be initiated in 7 days
Feeding practices in hemodynamically
unstable patients
• Clinical monitoring of gut functioning should be
started early when the patient is HD stable.
• Once the patient has been fluid resuscitated and
stabilized on declining doses of <2 vasopressors,
EN may be started cautiously at low rates.
• EN should be administered within 24–48 h once
the patient is stable with vasopressors.
• In persistent shock, early EN should be avoided.
HOW MUCH
• Dosing weight
– Actual weight
• Malnurished
• Normal weight
• Overweight
– Adjusted body weight
• Obese
• IBW + 0.25 (ABW - IBW)
• Calories
– 70% carbohydrate
– 30% fat
– Protein calories should not be calculated
– Start with 20 Kcal/kg
– Increase to 25-30 Kcal/kg at the end of week
– 35 Kcal/kg once stable in malnurished patient
• Protein
– Critically ill patients - 1.2 to 2 g/kg per day
– Severe burns - 2.0 g/kg per day
ROUTE
• Enteral - Preferred
– Oral
– NG
– NJ
• Parenteral – only when functional gut not
available
– TPN
– PPN
• Combined - no
ENTERAL
• Decrease the incidence of infection in critically
ill patients
• Preservation of gut immune function and
reduction of inflammation
• Clinically important and almost statistically
significant reduction in mortality
• Scientific formula feed should be preferred over
blenderized feeds to minimize feed contamination.
• Whenever feasible, closed system ready-to-hang
formula feeds should be preferred.
• Blenderized formulae are more likely to have bacterial
contamination than other hospital prepared diets.
• Hygienic methods of feed preparation, storage, and
handling of both formula feeds and blenderized feeds
are necessary.
• Continuous formula feeding with pumps or gravity
bags can be preferably done via fine bore tubes
ENTERAL
CONTRAINDICATIONS
• Unresuscitated shock
• Bowel obstruction
• Severe and protracted ileus
• Major upper gastrointestinal bleeding
• Intractable vomiting or diarrhea
• Gastrointestinal ischemia
POSTPYLORIC FEEDS(NJ)
• Prolonged inability to tolerate gastric feedings
• Gastric outlet obstruction
• Duodenal obstruction
• Gastric or duodenal fistula
• Severe gastroesophageal reflux
MONITORING
• GRV
– Not strictly recommended
– Closely monitor in patient with high risk of aspiration
– Can check every 4-6 hours
– Reintroduce if less then 500 ml or 50% of feeds
– Metoclopramide,erythromycin
– Electrolytes correction
• Abdominal distention
• Bowel movements
STANDARD
• Isotonic to serum
• Caloric density of approximately 1 kcal/mL
• Lactose-free
• Protein content of about 40 g/1000 mL
• Mixture of simple and complex carbohydrates
• Long-chain fatty acids
• Essential vitamins, minerals, and
micronutrients
CONCENTRATED
• Patient requiring volume restriction
• Hyperosmolar to serum
• Caloric density 1.5 - 2.0 kcal/mL
• Dumping syndrome if it is infused rapidly
– Nausea
– Shaking
– Diaphoresis
– diarrhea
• Not in post pyloric feeds
PREDIGESTED
• Content
– Short chain peptides
– Simple carbohydrates
– Short chain triglycerides
• Indications
– Short gut because it is generally well tolerated
– Digestive defects
– Failure to tolerate standard enteral nutrition
– Thoracic duct leak, chylothorax or chylous ascites
COMPLICATIONS
• Diarrhea
• Metabolic
• Aspiration
Prevention
– Backrest elevation
– Postpyloric feed
– Motility agents
– PEG
Disease-specific enteral
nutrition
IMMUNONUTRITION
• Omega-3 fatty acids
– antiinflammatory effect in the lung
• Glutamine
– 15 gm BD
– Hypercatabolic patients
– Burns
– Trauma
– Contraindicated in shock
• Ornithine ketoglutarate
– Glutamine precursor
OTHERS
• Vitamines and trace aliments
– Should be supplemented
• Fibres
– For treatment of diarrhoea / constipation
• Prebiotics / probiotics
– Antibiotic associated diarrhoea
HEPATIC FAILURE
• EN should be preferred in patients with acute
and/or chronic liver disease, admitted to ICU.
• No beneficial effects of branched-chain amino
acid formulations in critically ill patients with
encephalopathy who are receiving first-line
luminal antibiotics.
• Protein supplementation is recommended in
liver failure. Protein-energy determination
should be based on “dry” body weight or
usual weight instead of actual weight.
• Protein restriction should be avoided in
refractory encephalopathy.
• A whole-protein formula providing 35–40
kcal/kg body weight/day energy intake and
1.2–1.5 g/kg body weight/day protein is
recommended.
TRAUMATIC BRAIN INJURY
• Initiation of EEN after post trauma period (within
24–48 h of injury), once the patient is HD stable,
is recommended.
• Protein recommendations should be in the range
of 1.5–2.5 g/kg/day.
• Arginine-containing immune-modulating
formulations or eicosapentaenoic
acid/docosahexaenoic acid supplement with
standard enteral formula in TBI patients is
recommended.
ACUTE KIDENY INJURY
• Standard enteral formula is recommended for ICU patients
with AKI.
• Protein should not be restricted in patients with renal
insufficiency.
• Daily protein intake should be in the range of 1.2–1.7 g/kg
actual body weight in AKI patients.
• More protein on dialysis patient
• Provision of adequate non protein calories should be
maintained to achieve total energy intake in patients with AKI.
• In case of significant electrolyte imbalance, a specialty
formulation designed for renal failure should be considered.
• Low potassium and low phosphate diets can be implemented
where corresponding serum levels are high.
“To eat is a necessity, but to eat
intelligently is an art”
THANK YOU

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NUTRITION IN CRITICAL CARE

  • 1. NATIONAL GUIDELINES AND PROTOCOLS IN CRITICAL CARE NUTRITION PRACTICE DR ANKIT GAJJAR MD, IDCCM, IFCCM, EDIC CONSULTANT INTENSIVIST
  • 2. “Our food should be our medicine and our medicine should be our food” - Hippocrates
  • 3. INTRODUCTION • WHY? • WHEN? • HOW MUCH? • ROUTE? • CONTRAINDICATIONS? • COMPLICATIONS? • MONITORING? • DISEASE SPECIFIC
  • 4. WHY • Catabolic stress state • SIRS • Complications – Infectious – Morbidity – Multi-organ failure • Adequate nutrition – Attenuate metabolic response to stress – Favorably modulate immune responses – Decrease in length of hospital stay, morbidity rate and improvement in patient outcomes
  • 5. Nutrition Screening and Assessment • Indirect calorimetry – best method • Nutrition status of Indian malnourished patients can be assessed by SGA. • Initial monitoring of nutrition intervention must be done on daily basis and nutrition plans should be modified accordingly. • It is imperative that nutritional assessment is done by well-qualified and trained nutritionists, dedicated to the ICU. • Facilitation of nutrition assessment will require good coordination between intensivist and nutritionist.
  • 6. WHEN • As early as possible • At least in first 48 hours • HD instability – Start after shock resuscitation • Tube feed if cant achieve 50% of requirment in 72 hours • 100% in 7 days • Parenteral nutrition only if enteral nutrition cannot be initiated in 7 days
  • 7. Feeding practices in hemodynamically unstable patients • Clinical monitoring of gut functioning should be started early when the patient is HD stable. • Once the patient has been fluid resuscitated and stabilized on declining doses of <2 vasopressors, EN may be started cautiously at low rates. • EN should be administered within 24–48 h once the patient is stable with vasopressors. • In persistent shock, early EN should be avoided.
  • 8. HOW MUCH • Dosing weight – Actual weight • Malnurished • Normal weight • Overweight – Adjusted body weight • Obese • IBW + 0.25 (ABW - IBW)
  • 9. • Calories – 70% carbohydrate – 30% fat – Protein calories should not be calculated – Start with 20 Kcal/kg – Increase to 25-30 Kcal/kg at the end of week – 35 Kcal/kg once stable in malnurished patient • Protein – Critically ill patients - 1.2 to 2 g/kg per day – Severe burns - 2.0 g/kg per day
  • 10. ROUTE • Enteral - Preferred – Oral – NG – NJ • Parenteral – only when functional gut not available – TPN – PPN • Combined - no
  • 11. ENTERAL • Decrease the incidence of infection in critically ill patients • Preservation of gut immune function and reduction of inflammation • Clinically important and almost statistically significant reduction in mortality
  • 12. • Scientific formula feed should be preferred over blenderized feeds to minimize feed contamination. • Whenever feasible, closed system ready-to-hang formula feeds should be preferred. • Blenderized formulae are more likely to have bacterial contamination than other hospital prepared diets. • Hygienic methods of feed preparation, storage, and handling of both formula feeds and blenderized feeds are necessary. • Continuous formula feeding with pumps or gravity bags can be preferably done via fine bore tubes ENTERAL
  • 13. CONTRAINDICATIONS • Unresuscitated shock • Bowel obstruction • Severe and protracted ileus • Major upper gastrointestinal bleeding • Intractable vomiting or diarrhea • Gastrointestinal ischemia
  • 14. POSTPYLORIC FEEDS(NJ) • Prolonged inability to tolerate gastric feedings • Gastric outlet obstruction • Duodenal obstruction • Gastric or duodenal fistula • Severe gastroesophageal reflux
  • 15. MONITORING • GRV – Not strictly recommended – Closely monitor in patient with high risk of aspiration – Can check every 4-6 hours – Reintroduce if less then 500 ml or 50% of feeds – Metoclopramide,erythromycin – Electrolytes correction • Abdominal distention • Bowel movements
  • 16. STANDARD • Isotonic to serum • Caloric density of approximately 1 kcal/mL • Lactose-free • Protein content of about 40 g/1000 mL • Mixture of simple and complex carbohydrates • Long-chain fatty acids • Essential vitamins, minerals, and micronutrients
  • 17. CONCENTRATED • Patient requiring volume restriction • Hyperosmolar to serum • Caloric density 1.5 - 2.0 kcal/mL • Dumping syndrome if it is infused rapidly – Nausea – Shaking – Diaphoresis – diarrhea • Not in post pyloric feeds
  • 18. PREDIGESTED • Content – Short chain peptides – Simple carbohydrates – Short chain triglycerides • Indications – Short gut because it is generally well tolerated – Digestive defects – Failure to tolerate standard enteral nutrition – Thoracic duct leak, chylothorax or chylous ascites
  • 19. COMPLICATIONS • Diarrhea • Metabolic • Aspiration Prevention – Backrest elevation – Postpyloric feed – Motility agents – PEG
  • 21. IMMUNONUTRITION • Omega-3 fatty acids – antiinflammatory effect in the lung • Glutamine – 15 gm BD – Hypercatabolic patients – Burns – Trauma – Contraindicated in shock • Ornithine ketoglutarate – Glutamine precursor
  • 22. OTHERS • Vitamines and trace aliments – Should be supplemented • Fibres – For treatment of diarrhoea / constipation • Prebiotics / probiotics – Antibiotic associated diarrhoea
  • 23. HEPATIC FAILURE • EN should be preferred in patients with acute and/or chronic liver disease, admitted to ICU. • No beneficial effects of branched-chain amino acid formulations in critically ill patients with encephalopathy who are receiving first-line luminal antibiotics. • Protein supplementation is recommended in liver failure. Protein-energy determination should be based on “dry” body weight or usual weight instead of actual weight.
  • 24. • Protein restriction should be avoided in refractory encephalopathy. • A whole-protein formula providing 35–40 kcal/kg body weight/day energy intake and 1.2–1.5 g/kg body weight/day protein is recommended.
  • 25. TRAUMATIC BRAIN INJURY • Initiation of EEN after post trauma period (within 24–48 h of injury), once the patient is HD stable, is recommended. • Protein recommendations should be in the range of 1.5–2.5 g/kg/day. • Arginine-containing immune-modulating formulations or eicosapentaenoic acid/docosahexaenoic acid supplement with standard enteral formula in TBI patients is recommended.
  • 26. ACUTE KIDENY INJURY • Standard enteral formula is recommended for ICU patients with AKI. • Protein should not be restricted in patients with renal insufficiency. • Daily protein intake should be in the range of 1.2–1.7 g/kg actual body weight in AKI patients. • More protein on dialysis patient • Provision of adequate non protein calories should be maintained to achieve total energy intake in patients with AKI. • In case of significant electrolyte imbalance, a specialty formulation designed for renal failure should be considered. • Low potassium and low phosphate diets can be implemented where corresponding serum levels are high.
  • 27.
  • 28. “To eat is a necessity, but to eat intelligently is an art” THANK YOU