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Dr. Murali. U. M.S;
M.B.A.
Asso. Prof. of Surgery
IMS / MSU / Malaysia.
Hippocrates 400 B.C.
• Outline the indications & complications of
EN
• Outline the indications & complications of
TPN
• Illustrate with diagrams about Tube-
feeding
• Nutritional support is the
provision of nutrients to
patients who cannot
meet their nutritional
requirements by eating
standard diets.
• To meet the energy
requirement
for metabolic processes.
• To maintain a normal core
body
• Avoiding of malnutrition
• Enteral nutrition – Ideal one
• Overfeeding to be avoided
• Timing & Type of nutrition
• Nutrition therapy protein wasting
• Immunomodulators – glutamine,
arginine, omega 3 fatty acids – very
useful
• No single “ Gold Standard ”
• Body wt.loss > 10% - 6mths – prognostic index
Body mass index : weight (kg)/ height (m2)
[ <18 .5 – nutritional impairment ]
• Anthropometric measures – Indirect measures
- TSF / MAC – muscle & fat mass
• Transport proteins –
(Sr.alb.-30mg/dl, prealb.-12g/dl,transferrin-150mmol/L)
• Immune incompetence –
TLC / Delayed Hypersensitivity
• MUST - Tool
Severely Malnourished
Post – op complications
Trauma
Burns
Malignant disease
Renal & Liver failure
Short bowel syndrome
• Patient not expected to feed in 7
days
 Prolonged ileus or intestinal
obstruction
 Entero - cutaneous fistulas
 Pancreatitis, U C, Pyloric stenosis
 Major bowel surgery
• Esophageal replacement
• Gastric or colon surgery
• Whipple’s procedure
Duodenal Leak Gastro-duodeno-pancreatectomy
ESOPHAGECTOMY COLON REPLACEMENT
CAUSTIC INGESTION, ESOPHAGEAL STRICTURE
• Basic Needs
* 25-30 kcal/kg/day
• Hospitalized patients - TER
* 1300 - 1800 kcal/day – rough
• Basic Nutritional
Requirements
* Carbohydrates, fat,
proteins, vitamins minerals &
trace elements
• Feeding regimen – planned
* Standard tables - available
• For Carbohydrates - Glucose [40-
50%]
* 100-200 g/day
• For Fat - EFA [30-40%]
* 100-200 g/week
• For Protein – N2 [10-15%]
* 0.10-0.15g/kg/day (1.25g/kg/day)
Nutrition
Daily
Weekly
Fortnightly
Body wt. / Temp
CBC / RBS / BUN
I-O / electrolytes
Plasma proteins
LFT/ Acid-base status
Ca / Mg / Zn / Po4
U & P osmolality
Sr-Vit B12 / Iron / Folate
Sr-Lactate
Trace elements
• Enteral nutrition
• Parenteral nutrition
• More physiological
(liver not bypassed)
• Lesser cardiac work
• Safer and more efficient
• Better tolerated by the
patient
• Sip feeding
• NGT/ NDT/ NJT
• Gastrostomy
• Jejunostomy
• PEG (percutaneous
endoscopic
• Hemodynamic instability
• Intestinal Obstruction / GI bleed /
Ileus
• Intractable vomiting / Diarrhoea
• High output proximal fistula
• Inability to gain access
Severity
Tube – related
Gastro-intestinal
Metabolic
Infective
 Malposition /
Displacement
 Block / Break / Leakage
 Local complications
 N V D
 Aspiration
 Constipation
 Electrolyte disorders
 Vitamins / minerals Def.
 Drug interactions
> Exogenous / Endogenous
Total parenteral nutrition
(TPN) is defined as the
provision of all nutritional
requirements by means of
the I.V route & without the
use of GIT.
Patient not expected to
feed in 7 -10 days
Massive resection of small
bowel
High output fistulas
Prolonged intestinal failure
– some reasons
Central
Peripheral
• Central – Catheter is placed
using a needle & guide wire
via -
• Subclavian approach
• Internal jugular approach
• External jugular approach
Superior
Vena Cava
• Peripheral Parenteral Nutrition
* Through a peripherally inserted
central venous catheter. [PICC]
Catheter.
* Through a formal peripheral
venous line.
• Cardiac failure
• Blood dyscrasias
• Altered fat metabolism
Severity
Nutrition
Over - feeding
Sepsis
Line
 Hypoglycaemia/Ca/P/Mg
(refeeding syndrome)
 Chronic deficiency syndromes
(EFA, Zn, mineral and trace
elements)
 Glucose- Hyperglycaemia,
fluid retention, electrolyte abn.
 Fat- Hypertriglyceridemia
 A.A- Aminoacidaemia,
uraemia, metabolic acidosis
 Catheter related
 Systemic sepsis
 Drug interactions
> On insertion – PT / AE /
bleeding
> Long-term use - occlusion, VT
• Preserves gut integrity
• Possibly decreases bacterial translocation
• Preserves immunological function of gut
• Reduces costs
• Fewer infectious complications in critically ill patients
• Safer and more cost effective in many settings
• Is occurrence of severe fluid & electrolyte imbalance in
severely malnourished pts. while starting {RE-FEEDING}
EN/TPN. More common in TPN.
• Causes -
* ↓ Mg, ↓ Ca, & ↓ Po4 → myocardial dysfn.,
resp.changes, altered liver fns, convulsions & death.
• Commonly seen → chronic starvation, severe anorexia &
alcoholic pts.
• Gradual feeding & correction of Mg, Po4 & ca. & other
electrolytes & vitamins is important.
• It is becoming popular in Western countries.
• Indicated in Pts. who require nutrients for long term –
extensive Crohn’s, mesenteric infarction etc.
• Pt. uses the TPN fluids as advised at home. A
indweling Silastic catheter is designed for long term
use.
• Pt. should attend TPN clinic weekly – follow-up or any
complications.
• Pt. is psychologically comfortable & can attend his job
also.
Overfeeding
1980s
Enteral & Parenteral nutrition
Enteral & Parenteral nutrition

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Enteral & Parenteral nutrition

  • 1. Dr. Murali. U. M.S; M.B.A. Asso. Prof. of Surgery IMS / MSU / Malaysia.
  • 3. • Outline the indications & complications of EN • Outline the indications & complications of TPN • Illustrate with diagrams about Tube- feeding
  • 4. • Nutritional support is the provision of nutrients to patients who cannot meet their nutritional requirements by eating standard diets.
  • 5. • To meet the energy requirement for metabolic processes. • To maintain a normal core body
  • 6. • Avoiding of malnutrition • Enteral nutrition – Ideal one • Overfeeding to be avoided • Timing & Type of nutrition • Nutrition therapy protein wasting • Immunomodulators – glutamine, arginine, omega 3 fatty acids – very useful
  • 7. • No single “ Gold Standard ” • Body wt.loss > 10% - 6mths – prognostic index Body mass index : weight (kg)/ height (m2) [ <18 .5 – nutritional impairment ] • Anthropometric measures – Indirect measures - TSF / MAC – muscle & fat mass • Transport proteins – (Sr.alb.-30mg/dl, prealb.-12g/dl,transferrin-150mmol/L) • Immune incompetence – TLC / Delayed Hypersensitivity • MUST - Tool
  • 8.
  • 9. Severely Malnourished Post – op complications Trauma Burns Malignant disease Renal & Liver failure Short bowel syndrome
  • 10. • Patient not expected to feed in 7 days  Prolonged ileus or intestinal obstruction  Entero - cutaneous fistulas  Pancreatitis, U C, Pyloric stenosis  Major bowel surgery • Esophageal replacement • Gastric or colon surgery • Whipple’s procedure
  • 12. ESOPHAGECTOMY COLON REPLACEMENT CAUSTIC INGESTION, ESOPHAGEAL STRICTURE
  • 13. • Basic Needs * 25-30 kcal/kg/day • Hospitalized patients - TER * 1300 - 1800 kcal/day – rough • Basic Nutritional Requirements * Carbohydrates, fat, proteins, vitamins minerals & trace elements • Feeding regimen – planned * Standard tables - available
  • 14. • For Carbohydrates - Glucose [40- 50%] * 100-200 g/day • For Fat - EFA [30-40%] * 100-200 g/week • For Protein – N2 [10-15%] * 0.10-0.15g/kg/day (1.25g/kg/day)
  • 15. Nutrition Daily Weekly Fortnightly Body wt. / Temp CBC / RBS / BUN I-O / electrolytes Plasma proteins LFT/ Acid-base status Ca / Mg / Zn / Po4 U & P osmolality Sr-Vit B12 / Iron / Folate Sr-Lactate Trace elements
  • 16. • Enteral nutrition • Parenteral nutrition
  • 17.
  • 18. • More physiological (liver not bypassed) • Lesser cardiac work • Safer and more efficient • Better tolerated by the patient
  • 19. • Sip feeding • NGT/ NDT/ NJT • Gastrostomy • Jejunostomy • PEG (percutaneous endoscopic
  • 20.
  • 21. • Hemodynamic instability • Intestinal Obstruction / GI bleed / Ileus • Intractable vomiting / Diarrhoea • High output proximal fistula • Inability to gain access
  • 22. Severity Tube – related Gastro-intestinal Metabolic Infective  Malposition / Displacement  Block / Break / Leakage  Local complications  N V D  Aspiration  Constipation  Electrolyte disorders  Vitamins / minerals Def.  Drug interactions > Exogenous / Endogenous
  • 23.
  • 24. Total parenteral nutrition (TPN) is defined as the provision of all nutritional requirements by means of the I.V route & without the use of GIT.
  • 25. Patient not expected to feed in 7 -10 days Massive resection of small bowel High output fistulas Prolonged intestinal failure – some reasons
  • 27. • Central – Catheter is placed using a needle & guide wire via - • Subclavian approach • Internal jugular approach • External jugular approach Superior Vena Cava
  • 28. • Peripheral Parenteral Nutrition * Through a peripherally inserted central venous catheter. [PICC] Catheter. * Through a formal peripheral venous line.
  • 29.
  • 30.
  • 31. • Cardiac failure • Blood dyscrasias • Altered fat metabolism
  • 32. Severity Nutrition Over - feeding Sepsis Line  Hypoglycaemia/Ca/P/Mg (refeeding syndrome)  Chronic deficiency syndromes (EFA, Zn, mineral and trace elements)  Glucose- Hyperglycaemia, fluid retention, electrolyte abn.  Fat- Hypertriglyceridemia  A.A- Aminoacidaemia, uraemia, metabolic acidosis  Catheter related  Systemic sepsis  Drug interactions > On insertion – PT / AE / bleeding > Long-term use - occlusion, VT
  • 33. • Preserves gut integrity • Possibly decreases bacterial translocation • Preserves immunological function of gut • Reduces costs • Fewer infectious complications in critically ill patients • Safer and more cost effective in many settings
  • 34. • Is occurrence of severe fluid & electrolyte imbalance in severely malnourished pts. while starting {RE-FEEDING} EN/TPN. More common in TPN. • Causes - * ↓ Mg, ↓ Ca, & ↓ Po4 → myocardial dysfn., resp.changes, altered liver fns, convulsions & death. • Commonly seen → chronic starvation, severe anorexia & alcoholic pts. • Gradual feeding & correction of Mg, Po4 & ca. & other electrolytes & vitamins is important.
  • 35. • It is becoming popular in Western countries. • Indicated in Pts. who require nutrients for long term – extensive Crohn’s, mesenteric infarction etc. • Pt. uses the TPN fluids as advised at home. A indweling Silastic catheter is designed for long term use. • Pt. should attend TPN clinic weekly – follow-up or any complications. • Pt. is psychologically comfortable & can attend his job also.