Diphtheria is an upper respiratory tract disease caused by Corynebacterium diphtheriae bacteria. It is characterized by a pseudomembrane forming in the throat and nasal passages. The disease spreads through respiratory droplets from coughing or sneezing. Symptoms include sore throat and fever, with a gray or yellow membrane forming over the tonsils. It is diagnosed clinically and through laboratory isolation of the bacteria. Treatment involves antibiotics and bed rest, while prevention is through vaccination with the DPT vaccine.