Hereditary multiple exostoses (HME), also known as diaphyseal aclasis, is a rare genetic disorder characterized by multiple bony growths (exostoses) on the long bones. These exostoses are covered in cartilage and usually grow until after puberty, sometimes causing deformities or limiting movement. While the exostoses are generally benign, rare malignant transformation can occur in 1% of cases. Treatment may include surgical removal of symptomatic exostoses to relieve pain or correct deformities.