GERD ( Gasrtro-esophageal reflux disease )
Gastroesophageal reflux disease (GERD) is a condition in which the stomach contents (food or liquid) leak backwards from the stomach into the esophagus (the tube from the mouth to the stomach). This action can irritate the esophagus, causing heartburn and other symptoms.
And Case study at the end
A blockage of blood flow to the heart muscle. A heart attack is a medical emergency.A heart attack usually occurs when a blood clot blocks blood flow to the heart.Without blood,tissues loses oxygen and dies
2. a case study on hypertension with rheumatoid arthritis and erosive gastritisDr. Ajita Sadhukhan
A 50-year old female patient was admitted to the female medicine ward with complaints of anxiety and breathlessness since 7-8 days, decreased appetite and acidity. she was a known case of Rheumatoid Arthritis since 8 years . She was also a k/c/o hypertension since 10 years and had a past history of stroke.
A case study on anemia with congestive heart failuremartinshaji
a case dealing with a patient having anemia with congestive heart failure, this gives a clear idea about management, diagnosis, treatment , patient counselling, pharmacist interventions etc
please comment
thank u
A 50 year old female patient was admitted to the female medicine ward with complaints of constipation (today), breathlessness, coughing, b/l pedal oedema, anasarca since 7 days.
A soape note on uncontrolled hypertensionRomit Subba
This was our SOAPE note on Uncontrolled HTN. SOAPE S Stands for Subjective O stands for Objective A for Assessment P for Plan and E for Education . Patient have Uncontrolled HTN for which we being a pharmacist giving our rationale depending upon his/her SOAPE. Suggestions and comments are appreciated.
A CASE PRESENTATION ON CROHN'S DISEASE / A DETAILED CASE STUDY SLIDES martinshaji
A case presentation on crohns disease , which is one of the irritable bowel diseases which is commonly seen in gastroenterology dept . this is a case study of a patient affected with crohns , treatment options , diagnosis, pharmacist interventions, drugs given , lab investigations , discussion and detailed study regarding the condition is also mentioned . this was made for my academic purpose , hope it will be usefull for students from medical professions ,
THANK YOU
MARTIN SHAJI
Also called as diabetes mellitus. A group of diseases that result in too much sugar in the blood.Most common types of diabetes are; type 2 diabetes, type 1 diabetes, prediabetes, gestational diabetes.
GERD ( Gasrtro-esophageal reflux disease )
Gastroesophageal reflux disease (GERD) is a condition in which the stomach contents (food or liquid) leak backwards from the stomach into the esophagus (the tube from the mouth to the stomach). This action can irritate the esophagus, causing heartburn and other symptoms.
And Case study at the end
A blockage of blood flow to the heart muscle. A heart attack is a medical emergency.A heart attack usually occurs when a blood clot blocks blood flow to the heart.Without blood,tissues loses oxygen and dies
2. a case study on hypertension with rheumatoid arthritis and erosive gastritisDr. Ajita Sadhukhan
A 50-year old female patient was admitted to the female medicine ward with complaints of anxiety and breathlessness since 7-8 days, decreased appetite and acidity. she was a known case of Rheumatoid Arthritis since 8 years . She was also a k/c/o hypertension since 10 years and had a past history of stroke.
A case study on anemia with congestive heart failuremartinshaji
a case dealing with a patient having anemia with congestive heart failure, this gives a clear idea about management, diagnosis, treatment , patient counselling, pharmacist interventions etc
please comment
thank u
A 50 year old female patient was admitted to the female medicine ward with complaints of constipation (today), breathlessness, coughing, b/l pedal oedema, anasarca since 7 days.
A soape note on uncontrolled hypertensionRomit Subba
This was our SOAPE note on Uncontrolled HTN. SOAPE S Stands for Subjective O stands for Objective A for Assessment P for Plan and E for Education . Patient have Uncontrolled HTN for which we being a pharmacist giving our rationale depending upon his/her SOAPE. Suggestions and comments are appreciated.
A CASE PRESENTATION ON CROHN'S DISEASE / A DETAILED CASE STUDY SLIDES martinshaji
A case presentation on crohns disease , which is one of the irritable bowel diseases which is commonly seen in gastroenterology dept . this is a case study of a patient affected with crohns , treatment options , diagnosis, pharmacist interventions, drugs given , lab investigations , discussion and detailed study regarding the condition is also mentioned . this was made for my academic purpose , hope it will be usefull for students from medical professions ,
THANK YOU
MARTIN SHAJI
Also called as diabetes mellitus. A group of diseases that result in too much sugar in the blood.Most common types of diabetes are; type 2 diabetes, type 1 diabetes, prediabetes, gestational diabetes.
The number of people with diabetes rose from 108 million in 1980 to 422 million in 2014.
Prevalence has been rising more rapidly in low and middle-income countries than in
high-income countries.
Diabetes is a major cause of blindness, kidney failure, heart attacks, stroke, and lower
limb amputation.
Between 2000 and 2016, there was a 5% increase in premature mortality from diabetes.
In 2019, an estimated 1.5 million deaths were directly caused by diabetes. Another 2.2 million deaths were attributable to high blood glucose in 2012.
A healthy diet, regular physical activity, maintaining a normal body weight, and avoiding tobacco use are ways to prevent or delay the onset of type 2 diabetes.
Diabetes can be treated and its consequences avoided or delayed with diet, physical activity, medication, and regular screening and treatment for complications
This is a presentation describing the management principles of a newly diagnosed diabetic patient, including, diet therapy, medical treatment and exercise
CASE PRESENTATION ON SYSTEMIC HYPERTENSION IN SOAP FORMAT.pptxHome
Systemic hypertension, or high blood pressure, is a chronic condition characterized by elevated pressure in the arteries. Typically measured in millimeters of mercury (mmHg), it's diagnosed when readings consistently exceed 130/80 mmHg. This condition, often symptomless, increases the risk of serious health complications like heart disease, stroke, and kidney failure. Contributing factors include genetics, age, unhealthy lifestyle habits, obesity, and stress. Treatment involves lifestyle changes—such as a healthy diet, regular exercise, and stress management—and, if necessary, medications to lower blood pressure. Regular monitoring and management are crucial to mitigate risks and maintain overall health.
Gluteal abscess with diabetes mellitus and diabetic ketoacidosis (2)Goutham Kondeti
About the patient with Diabetes mellitus and ketoacidosis with abscess, his treatment plan, goals of treatment, monitoring parameters, drug interactions, patient counseling, precautions
CASE STUDY ON CHRONIC KIDNEY DISEASE.pptxdrsriram2001
Chronic Kidney Disease (CKD) is a progressive condition characterized by the gradual loss of kidney function over time. Here's a comprehensive explanation of CKD in four steps:
Causes and Risk Factors: CKD can result from various underlying conditions or risk factors that damage the kidneys' filtering units (nephrons) and impair their function. Common causes and risk factors include:
Diabetes: High blood sugar levels over time can damage the blood vessels in the kidneys.
Hypertension (high blood pressure): Elevated blood pressure can strain the kidneys' blood vessels and impair kidney function.
Glomerulonephritis: Inflammation of the kidney's filtering units can lead to scarring and loss of function.
Polycystic kidney disease: Inherited disorder characterized by the growth of cysts in the kidneys, leading to kidney enlargement and loss of function.
Prolonged obstruction of the urinary tract: Conditions such as kidney stones or an enlarged prostate can obstruct urine flow, leading to kidney damage.
Autoimmune diseases: Conditions like lupus or vasculitis can cause inflammation and damage to the kidneys.
Certain medications: Long-term use of certain medications, such as nonsteroidal anti-inflammatory drugs (NSAIDs) or some antibiotics, can contribute to kidney damage.
Stages and Progression: CKD is typically classified into five stages based on the estimated glomerular filtration rate (eGFR), which measures how well the kidneys are filtering waste from the blood. The stages are as follows:
Stage 1: Kidney damage with normal or high eGFR (≥90 mL/min/1.73 m²)
Stage 2: Mild decrease in eGFR (60-89 mL/min/1.73 m²)
Stage 3: Moderate decrease in eGFR (30-59 mL/min/1.73 m²)
Stage 4: Severe decrease in eGFR (15-29 mL/min/1.73 m²)
Stage 5: Kidney failure (eGFR <15 mL/min/1.73 m² or dialysis)
CKD progresses slowly over time, and symptoms may not be apparent until the later stages when significant kidney damage has occurred.
Symptoms and Complications: In the early stages, CKD may be asymptomatic, and symptoms may only become evident as kidney function declines. Common symptoms and complications of CKD include:
Fatigue and weakness
Swelling of the legs, ankles, or feet (edema)
Shortness of breath
Nausea and vomiting
Itching
Loss of appetite
Muscle cramps
Difficulty concentrating
Electrolyte imbalances (e.g., high potassium levels)
Bone disease (e.g., osteoporosis)
Anemia
Complications of advanced CKD include cardiovascular disease, fluid overload, electrolyte imbalances, and kidney failure requiring dialysis or kidney transplantation.
Management and Treatment: The management of CKD aims to slow the progression of the disease, manage symptoms, and prevent complications. Treatment may involve:
Lifestyle modifications: Maintaining a healthy diet low in salt, potassium, and phosphorus, exercising regularly, maintaining a healthy weight, and quitting smoking.
Blood pressure control: Medications such as ACE inhibitors
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
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ASA GUIDELINE
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New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
1. PRESENTED BY
KAVIYA AP
DOCTOR OF PHARMACY
DEPARTMENT OF PHARMACY PRACTICE
SRM COLLEGE OF PHARMACY, SRM INSTITUTE OF SCIENCE & TECHNOLOGY, KATTANKULATHUR
CASE PRESENTATION ON
DIABETES CARDIOMYOPATHY
2. SUBJECTIVE EVIDENCE
2
NAME Mr.X
AGE 55 Years
GENDER Male
WEIGHT / HEIGHT 68 kg / 168 cm
BMI 24
MARITAL STATUS Married
OCCUPATION Engineer
DEPARTMENT Cardiology
D.O.A / D.O.D 07.06.19 /16.06.19
TOATL NO.OF STAY 9 Days
3. REASON FOR ADMISSION Breathlessness
Squeezing
Heartburn
Coldsweat Since morning
HOPI Nausea, indigestion
PAST MEDICAL HISTORY Hypertension x 5 years
Diabetes mellitus type II x 5 years
PAST MEDICATION HISTORY T.Glycomet 500mg
T.Propanolol 20mg
PERSONAL HISTORY Mixed diet
Occasional drinks
Non- smoker
Psychological – normal
FAMILY HISTORY PARENTS - Hypertension
3
4. 4
GENERAL EXAMINATION PHYSICAL EXAMINATION
Temperature : 98.6 F
BP : 120/80 mm Hg
PR : 68 beats/min
RR : 22 cycle/min
SYSTEMIC EXAMINATION
CVS : S1S2 +
CNS : NFND
RS : NVBS
P/A : soft , no bowel sounds
INVESTIGATIONS DONE •Complete blood count
•Liver function test
•Renal function test
•Urine test
•ECG
7. 7
08/06/19
12/06/19
ECG
ECHO
PAIN ASSESSMENT :
PROCEDURE :
CORONARY
ANGIOGRAM
Left axis deviation
Incomplete RBBB
Global hypokinesia
Severe LV dysfunction
MR mild
No pain - 0
The study reveled distal left main with multi
vessel disease and advised patient and
attenders to do CABG.
9. PLAN
9
THERAPEUTIC GOALS
• To maintain the normal blood sugar levels.
• To enable the patient symptoms free.
• To prevent the progression of the disease and its complications.
• To improve the quality of life of the patient.
10. 1. Inj. LASIX
FUROSEMIDE
20mg IV BD DAY 1-9
2. T. CLOPILET
CLOPIDOGREL
75mg oral OD DAY 1-9
3. T.FLAVEDON
TRIMETAZIDINE
35mg oral BD DAY 1-9
4. T. ATORVASTATIN 20mg oral HS DAY 1-9
5. T.NITROCONTIN
NITRO GLYCERIN
2.6mg oral BD DAY 6-9
6. T.CARDIVAS
CARVEDILOL
3.125mg oral BD DAY 6-9
7. T.RANTAC
RANITIDINE
150mg oral BD DAY 6-9
8. T.ANXIT
ALPRAZOLAM
0.25mg oral HS DAY 8-9
10
MEDICATION CHART
11. PHARMACIST INTERVENTION
S.NO DRUG NAME DOSE ROA FREQ DAYS
1. T. ATORVASTATIN 20mg Oral HS DAY 1-9
11
PRESCRIPTION ERROR :
Statins will increase the sugar level in blood. Therefore it is better to
administer other class of lipid lowering drug to the patient.
Eg. Niacin 50-100mg PO
MISSED DRUG :
Pt had a complaint of nausea and vomiting sensation.
Addition of ondansetron-4mg may relieve from his symptoms.
12. DRUG - DRUG INTERACTIONS :
Moderate
Furosemide + Carvedilol
Carvedilol increase the effect of furosemide and decrease the
potassium level in the blood. Monitor closely serum potassium level.
DRUG – DISEASE INTERACTIONS:
HMG CoA REDUCTASE ENZYME INHBITORS + DIABETES
Increase in HbA1c and fasting serum glucose levels.Alternate drug
must be used.
DRUG – FOOD INTERACTION :
Carvedilol + caffeine
Avoid taking coffee along with T.Carvedilol
12
13. DISCHARGE SUMMARY
13
1. T. CLOPILET 75mg oral OD
2. T.FLAVEDON 35mg oral BD
3. T. ATORVASTATIN 20mg oral HS
4. T.NITROCONTIN 2.6mg oral BD
5. T.CARDIVAS 3.125mg oral BD
6. T.RANTAC 150mg oral BD
7. T.ANXIT 0.25mg oral HS
The patient and attender wanted to get discharged and come again
later. The patient was discharged with following medications.
15. DISEASE COUNSELING
Diabetes cardiomyopathy is a disorder of the heart muscle in the
people with diabetes.
It can lead to inability of the heart to circulate blood throughout the
body effectively.
Treating the initial problem early can prevent the complication of the
disease.
Following a healthy diet with low glycemic index can lower the blood
sugar level.
15
16. DRUG COUNSELING
Follow 4S in drug meditation : Do not share,stop, skip and sum the doses
of the prescribed drugs.
A pill organizer or pill container is best way for medication adherence
and keeping alarm can help patient to take medications at correct time.
Do not take T.Furosemide more than it is recommended.
T.Nitrocontin can cause dizziness. Do not drive or operate heavy machinery
while taking this drug.
16
17. DIET COUNSELING
To combat the dawn phenomenon, eat high fiber and low fat snack before
going to bed like wheat crackers or an apple.
Diabetes can lead to low hemoglobin concentration. Therefore eat foods
rich in Iron content- dates,greens,broccoli and dry fruits.
Eat foods with heart healthy fats : olive oil and tuna fish(soorai) and salmon
fish(sankara)
17
18. Limit foods and drinks that includes saturated fats,high in sodium,
beverages with added sugars.
Make every meal well balanced :The key for eating diabetes is to eat a
variety of heathy foods from all food groups,
Vegetables – Starchy : potatoes , corn.
Non starchy : carrot ,greens, peppers.
Fruits : orange, lemon , berries, bananas.
Grains : wheat , rice ,oats.
Protein : fish , eggs , dried peas.
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19. Plate method
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• Use a nine inch plate.
• Fill half of the plate with non-starchy foods.
• Fill one quarter of plate with whole grain or starchy foods and
remaining quarter with lean protein foods.
• Patient can also have one glass of milk and few parts of fruits in bowl.
20. Lower high blood pressure- limit salt intake in diet
Be physically active everyday- exercise 15 mins a day.
Walk at least 10 mins a day.
Aim for healthy weight – do not eat food that increase
your weight.
Manage diabetes – follow sugar controlled diet
Reduce stress – do meditation to relieve from stress.
Limit alcohol – cessation of alcohol is good for heart.
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LIFESTYLE MODIFICATION
21. TO CONTROL SUGAR
Sleep at right time : If amount of sleep decreases, blood sugar level
increases. So sleep for 8-10 hours for normal functioning of body and
also for the production of RBCs.
Coconut a week : It maintains blood sugar and A1c and its a good
source of magnesium which may increase insulin sensitivity and
reduce blood sugar level.
Get body hydrated : Drink enough water to keep body hydrated and
it helps body in eliminating excess of glucose from the body.
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22. TO PREVENT FURTHER COMPLICATIONS :
Candy in a pocket : Whenever there is giddiness , eat a candy to
overcome it.
Vision test : A comprehensive eye exam should be taken to check
the functioning of eyes and to avoid cataract and other vision
problems.
Regular checkup : get regular checkup in hospital for every three
months.
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23. For drug dose , drug interactions and patient counseling :
Secondary source:
Pharmacotherapy handbook – 9th edition by Joseph.T.Dipiro
BNF 76
Teritary source :
www.mayoclinic.org
www.micromedex.com
www.wemmd.com
www.healthline.com
www.medscape.com
23
REFERENCE