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CASE
PRESENTATION ON
TYPE 2 DIABETES MELLITUS
Submitted by : B.RAJU
Pharm D 2 Year
19HF1TOOO5
Submitted to : Dr. sridevi mam
INTRODUCTION:
Type 2 diabetes formerly knows as adult onset disease is a form of
diabetes that is characterised by high blood sugar, insulin resistance and
lack of insulin
With type 2 diabetes ,the body either doesn’t produce enough insulin(beta
cells) ,or it resists insulin
ETIOLOGY
• Resistant of insulin
• Genetic predisposition
• obesity
 SYMPTOMS:
Polyuria , Polydipsia ,Polyphagia
Weight loss , Blurred vision , Fatigue
Headache , Poor wound healing
 Diagnosis :
Type 2 diabetes mellitus can be diagnosis by blood
test i.e fasting blood glucose , oral glucose tolerance
test ; following strict diet ,weight loss , healthy
eating , exercise and through medications
PATHOPHYSIOLOGY
TREATMENT
ORAL HYPOGLCEMIC AGENTS
• Alpha – glucosidase inhibitors : acarbose
• Biguanides :metformin
• Thiazolidinediones : rosiglitazones
• Sulfonylureas : glipizide ,glyburide , glimperide
• Meglinitides : repaglinide
• Phenylalanine derivatives : nataglinide
• DPP- IV inhibitors : sitagliptin ,saxagliptin
SUBJECTIVE DATA
Name : B . Dathaiaha
Dr name : k .s . ashok kumar
Age : 81 yrs
IP no: IP210301076
Sex : male
Ward : male medicine ward
Unit : 1 ; DOA : 1/3/2021
c/o : patient came for cataract surgery , k/c/o : DM ,
HTN
PMHx : patient was asymptomatic for 1 month and decrease
vision suffering from HTN (20 years) ; type 2 diabetes mellitus (20
years )
FMHx : Not significant
SHx : mixed diet , bladder movement regular , smoker , alcholic
VITALS :
Temperature : Afebrile
Pulse rate :76
CVS:s1s2 +ve
Respiratory rate :18cycles /min
Respiratory system : BAE +ve
OBJECTIVE DATA
Hb 11.8gm%
RBC count 4.3m/cmm
T. WBC 8900cell/cmm
Neutrophills 68%
Lymphocyts 23%
eosnophills 02%
Monocytes 07%
Basophills 00 %
Platelets 2.6 lakhs/c
Hematology
Bilirubin total 0.5mg/ml
direct 0.2mg/dl
AST(SCOT) 23u/l
ALT (SGPT ) 20U/L
ALP 120 gm%
Total protein 7.5gm%
Albumin 3.9gm%
Globulin 3.6gm%
LFT
FBS 251mg/ml
PPBS 276mg/ml
RBS 568mg/ml
HbAIC 9.9%
B.Urea 91mg/dl
Sr. creatinine 2.7mg/ml
Biochemistry
s. Cholesterol 157 mg/dl
HDL 72mg/dl
TG 117mg/dl
LDL 62 mg/dl
TC/HDL 157 mg/dl
Lipid profile Urine analysis
Appearance Clear
Colour Pale yellow
Reaction 5.0
Specific gravity 1.015
ASSESMENT
• Base on the subjective and objective data the patient
has been diagnosed with type 2 diabetes mellitus
• Provisional diagnosis : type diabetes mellitus with
uncontrolled blood sugar
• Final diagnosis : diabetes mellitus type 2
PLAN
Current drugs Dose Frequency ROA Generic name Comment
Inj .insuman comb BD IV Insuman comb To reduce glucose
levels
Tab vildagliptin 50mg OD PO Vildagliptin To treat diabetes
Tab ceruvin 5mg OD PO Clopidogrel Antiplatelet agent
Tab Bio D3 0.25mg OD PO Calcitriol Chronic renal
dialysis
Tab homo DIP 5mg OD PO Methylcobalamine Vit B12 & folic
acid supplement
Tab strovas 40mg OD PO Atorvastatin To treat
hyperlipedmia
Tab met XL 12.5mg OD PO metoprolol Hypertension
Tab dytor 10mg OD PO Torsemide Hypertension and
CHF
Rx
Tab climidipine 10mg OD PO Clinidipine High bp
Tab angiospan 10mg OD PO Glyceryl
trinitrate
To treat angina
pectoris
Tab rabee 10mg OD PO Rabeprazole Proton pump
inhibitor
Tab febuday 40mg OD PO Febuxostat Anti gout
medicine
Tab Sorbinitrate 5mg OD PO Iso dinitate To treat chest
pain
PHARMACIST INTERVENTION
• The patient is advised to go with electrolytes test
because as the sugar and sugar subtitutes can cause
spiking in blood sugar levels maintaining your
electrolyte balance is crucial , in this cause it is
important
DRUG INTERACTIONS
• ATORVASTATIN ↔ CLOPIDROGEL
This combination may reduce the effects of clopidrogel, if you have any
signs of blood clots ,shortness of breath ,sudden loss of vision swelling
immediately consult an physician
• METOPROLOL ↔ TORSEMIDE
This may lower blood pressure and slows your heart rate causes
dizziness
DRUG FOOD INTERACTIONS
Grape juice can increase the blood levels of atorvastatin this can increase
the liver damage and leads to RHABDOMYLOSIS
PATIENT COUNSELLING
About disease :
It is a lifelong disease and it needs necessary modifications in the lifestyle
pattern strictly use the prescribed medication
About drugs :
• If we skip the dose ,should not double the dose
• Take prescribed medications at right time
• TAB rabee should be taken in the morning before breakfast
• Be careful while taking insulin (INSUMAN COMB) should be taken 30
minutes before food ; insulin should be stored in refrigerator
• Take isosorbide dinitrate during emergency only
LIFE STYLE MODIFICATIONS
• Eat healthy get plenty of vegetables such as carrot ,broccoli beans ,cabbage
& fruits such as carrot ,kiwi ,banana mango
• Choose non fat dairy and lean meats
• 30 minutes of Exercise such as walk, gym this may reduce your stress and
brings your sugar levels down
• Get regular checkups
• Manage stress through yoga breathing exercise
• Stop smoking and alchol
• Maintain healthy body weight
• Enough sleep
DIET CHART
• Carbohydrates such as brown rice, whole wheat , oat meal
foods to avoid white bread , sugar flour cookies
• Protein food such as beans, legumes, eggs, seafood, dairy,
poultry
• Include chia seeds , apple cider vinegar
References
• drugs.com ( www.drugs.com )
• medscape ( www.Medscape.com )
• Comprehensive pharmacy by LEON
SHARGEL
• Pharmacotherapy by joseph T dipiro
• Pharmacology by K.D TIRPATI
Diabetes mellitus

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Diabetes mellitus

  • 1. CASE PRESENTATION ON TYPE 2 DIABETES MELLITUS Submitted by : B.RAJU Pharm D 2 Year 19HF1TOOO5 Submitted to : Dr. sridevi mam
  • 2. INTRODUCTION: Type 2 diabetes formerly knows as adult onset disease is a form of diabetes that is characterised by high blood sugar, insulin resistance and lack of insulin With type 2 diabetes ,the body either doesn’t produce enough insulin(beta cells) ,or it resists insulin ETIOLOGY • Resistant of insulin • Genetic predisposition • obesity
  • 3.  SYMPTOMS: Polyuria , Polydipsia ,Polyphagia Weight loss , Blurred vision , Fatigue Headache , Poor wound healing  Diagnosis : Type 2 diabetes mellitus can be diagnosis by blood test i.e fasting blood glucose , oral glucose tolerance test ; following strict diet ,weight loss , healthy eating , exercise and through medications
  • 5. TREATMENT ORAL HYPOGLCEMIC AGENTS • Alpha – glucosidase inhibitors : acarbose • Biguanides :metformin • Thiazolidinediones : rosiglitazones • Sulfonylureas : glipizide ,glyburide , glimperide • Meglinitides : repaglinide • Phenylalanine derivatives : nataglinide • DPP- IV inhibitors : sitagliptin ,saxagliptin
  • 6. SUBJECTIVE DATA Name : B . Dathaiaha Dr name : k .s . ashok kumar Age : 81 yrs IP no: IP210301076 Sex : male Ward : male medicine ward Unit : 1 ; DOA : 1/3/2021 c/o : patient came for cataract surgery , k/c/o : DM , HTN
  • 7. PMHx : patient was asymptomatic for 1 month and decrease vision suffering from HTN (20 years) ; type 2 diabetes mellitus (20 years ) FMHx : Not significant SHx : mixed diet , bladder movement regular , smoker , alcholic VITALS : Temperature : Afebrile Pulse rate :76 CVS:s1s2 +ve Respiratory rate :18cycles /min Respiratory system : BAE +ve
  • 8. OBJECTIVE DATA Hb 11.8gm% RBC count 4.3m/cmm T. WBC 8900cell/cmm Neutrophills 68% Lymphocyts 23% eosnophills 02% Monocytes 07% Basophills 00 % Platelets 2.6 lakhs/c Hematology Bilirubin total 0.5mg/ml direct 0.2mg/dl AST(SCOT) 23u/l ALT (SGPT ) 20U/L ALP 120 gm% Total protein 7.5gm% Albumin 3.9gm% Globulin 3.6gm% LFT FBS 251mg/ml PPBS 276mg/ml RBS 568mg/ml HbAIC 9.9% B.Urea 91mg/dl Sr. creatinine 2.7mg/ml Biochemistry
  • 9. s. Cholesterol 157 mg/dl HDL 72mg/dl TG 117mg/dl LDL 62 mg/dl TC/HDL 157 mg/dl Lipid profile Urine analysis Appearance Clear Colour Pale yellow Reaction 5.0 Specific gravity 1.015
  • 10. ASSESMENT • Base on the subjective and objective data the patient has been diagnosed with type 2 diabetes mellitus • Provisional diagnosis : type diabetes mellitus with uncontrolled blood sugar • Final diagnosis : diabetes mellitus type 2
  • 11. PLAN Current drugs Dose Frequency ROA Generic name Comment Inj .insuman comb BD IV Insuman comb To reduce glucose levels Tab vildagliptin 50mg OD PO Vildagliptin To treat diabetes Tab ceruvin 5mg OD PO Clopidogrel Antiplatelet agent Tab Bio D3 0.25mg OD PO Calcitriol Chronic renal dialysis Tab homo DIP 5mg OD PO Methylcobalamine Vit B12 & folic acid supplement Tab strovas 40mg OD PO Atorvastatin To treat hyperlipedmia Tab met XL 12.5mg OD PO metoprolol Hypertension Tab dytor 10mg OD PO Torsemide Hypertension and CHF Rx
  • 12. Tab climidipine 10mg OD PO Clinidipine High bp Tab angiospan 10mg OD PO Glyceryl trinitrate To treat angina pectoris Tab rabee 10mg OD PO Rabeprazole Proton pump inhibitor Tab febuday 40mg OD PO Febuxostat Anti gout medicine Tab Sorbinitrate 5mg OD PO Iso dinitate To treat chest pain
  • 13. PHARMACIST INTERVENTION • The patient is advised to go with electrolytes test because as the sugar and sugar subtitutes can cause spiking in blood sugar levels maintaining your electrolyte balance is crucial , in this cause it is important
  • 14. DRUG INTERACTIONS • ATORVASTATIN ↔ CLOPIDROGEL This combination may reduce the effects of clopidrogel, if you have any signs of blood clots ,shortness of breath ,sudden loss of vision swelling immediately consult an physician • METOPROLOL ↔ TORSEMIDE This may lower blood pressure and slows your heart rate causes dizziness DRUG FOOD INTERACTIONS Grape juice can increase the blood levels of atorvastatin this can increase the liver damage and leads to RHABDOMYLOSIS
  • 15. PATIENT COUNSELLING About disease : It is a lifelong disease and it needs necessary modifications in the lifestyle pattern strictly use the prescribed medication About drugs : • If we skip the dose ,should not double the dose • Take prescribed medications at right time • TAB rabee should be taken in the morning before breakfast • Be careful while taking insulin (INSUMAN COMB) should be taken 30 minutes before food ; insulin should be stored in refrigerator • Take isosorbide dinitrate during emergency only
  • 16. LIFE STYLE MODIFICATIONS • Eat healthy get plenty of vegetables such as carrot ,broccoli beans ,cabbage & fruits such as carrot ,kiwi ,banana mango • Choose non fat dairy and lean meats • 30 minutes of Exercise such as walk, gym this may reduce your stress and brings your sugar levels down • Get regular checkups • Manage stress through yoga breathing exercise • Stop smoking and alchol • Maintain healthy body weight • Enough sleep
  • 17. DIET CHART • Carbohydrates such as brown rice, whole wheat , oat meal foods to avoid white bread , sugar flour cookies • Protein food such as beans, legumes, eggs, seafood, dairy, poultry • Include chia seeds , apple cider vinegar
  • 18. References • drugs.com ( www.drugs.com ) • medscape ( www.Medscape.com ) • Comprehensive pharmacy by LEON SHARGEL • Pharmacotherapy by joseph T dipiro • Pharmacology by K.D TIRPATI