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DAMAGE
CONTROL
ORTHOPAEDICS
Mohamed Elshohna ,Orthopaedic registrar
,Aladan hospital
DCO
• Rapid emergency surgery to save life or limb – NOT
involving complex reconstructive surgery
• Control bleeding
• Decompress cranium, pericardium, thorax, abdomen and limbs
• Decontaminate wounds and ruptured viscera
• Splint fractures
• Cast, traction, pelvic binder, ex-fix
• Get back to ITU environment ASAP
• Definitive surgery performed several days later
SIRS 1983
SYSTEMIC IMMUNE RESPONSE SYNDROME
• Condition characterised by systemic inflammation, organ dysfunction,
and organ failure.
• Subset of cytokine storm, abnormal regulation of various cytokines
• Inflammatory response to sepsis, trauma, hypoperfusion
CARS 1996
COMPENSATORY ANTI-INFLAMMATORY RESPONSE SYNDROME
• CARS - systemic deactivation of the immune system tasked with restoring
homeostasis from an inflammatory state
• More than just cessation of SIRS
Bone RC. Sir Isaac Newton, sepsis, SIRS, and CARS. Crit Care Med. 1996;24(7):1125–8
THE ‘FIRST HIT’
Threshold for
fatal
inflammatory
response
DEATH: from multiorgan failure or adult
respiratory distress syndrome
1st Hit: the trauma
inflammatory
response
time
The ‘natural’ systemic
inflammatory response
THE ‘SECOND HIT’
Threshold for
fatal
inflammatory
response
1st Hit: the trauma
inflammatory
response
time
2nd Hit: the surgery
The exaggerated
response brought
about by the 2nd hit of
surgery
THE ‘SECOND HIT’
Threshold for
fatal
inflammatory
response
1st Hit: the trauma
inflammatory
response
time
2nd Hit: the surgery
In some individuals the lengthy
surgery of early total care
exacerbates the the systemic
inflammatory response resulting in
death
LETHAL TRIAD
Acidosis
Hypothermia
Coagulopathy
POLYTRAUMA
POLYTRAUMA
• Defined as “a clinical state following injury to the body leading
to profound physiometabolic changes involving multisystem’’.
• Patient with anyone of the following combination of injuries
TWO MAJOR SYSTEM INJURY + ONE MAJOR LIMB INJURY.
ONE MAJOR SYSTEM INJURY + TWO MAJOR LIMB INJURY.
ONE MAJOR SYSTEM INJURY + ONE OPEN GRADE III SKELETAL
INJURY.
UNSTABLE PELVIS FRACTURE WITH ASSOCIATED VISCERAL
INJURY.
• The term “polytrauma” has been frequently defined in
terms of a high Injury Severity Score
• The internationally accepted threshold of an ISS 16 is
based on the description as being predictive of a mortality
risk above 10% .
Boyd, C.R.; Tolson, M.A.; Copes,W.S. Evaluating trauma care: The TRISS method. Trauma Score and
the Injury Severity Score. J. Trauma 1987, 27, 370–378. [CrossRef] [PubMed]
PATIENTS FOR DC SURGERY
• 4 groups of patients
• Stable: go for Early Total Care
• Borderline: ?
• Unstable: go for Damage Control Surgery
• Extremis: Damage Control Surgery or ITU
• Borderline patients are more difficult to define
TIMING OF RETURN AFTER DC
SURGERY
• Days 2-5 are not safe
• During this period:
• Marked inflammatory response ongoing
• Increased capillary permeability leads to generalized oedema
• Cardiac output is high
• Patient is fragile
• A 2nd hit at this stage could be fatal
• Pape et al: prospective study –
• multiply injured patients undergoing surgery between days 2 and 4
had a significantly increased inflammatory response compared with
patients operated on between days 6 and 8
JTO; Volume 02 / Issue 02 / May 2014
EAP
• Early Appropriate Care
• Acceptance different patients respond differently to first and second hits
• Consider severity of initial injury
• Consider response to resuscitation
• What further surgery required
• Continued re assessment and ability to change from ETO TO DCO
20 YO, MALE
01/02/06 – 15:48
• #BOS
• #Nasal bone
• APC pelvic injury
• # R Supracondylar femur
• # R Tibia shaft (open)
• # L Tibial plateau (open)
• # Bimalleolar L ankle
PRE HOSPITAL
• Intubated
• Pre hospital arrest
• Hr 144, Systolic 60
• GCS 3
ED
C CLAMP
BINDER
SPLINT
• External fixator
• Pelvis
• R leg
• L leg
• Debridement washout,
fasciotomy and vac dressing
• R thigh
• R lower leg
• L lower leg
• Laparotomy
4 HRS
• Plating pubic symphysis
• Intramedullary nail
• R femur retrograde
• R tibia
• Change of Vacs
Day 6
• ORIF L Tibial plateau
• ORIF L fibula
• Free Flap R tibia
• Rotation flap L Tibia
Day 9
SUMMARY
• Multiply injured patients may have a profound and
life-threatening inflammatory response
• A ‘second hit’ of long definitive surgery can result in
a fatal inflammatory response
• The second hit can be avoided using early ‘damage
control surgery’ followed by late ‘definitive care’
Damage control

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Damage control

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  • 7. DCO • Rapid emergency surgery to save life or limb – NOT involving complex reconstructive surgery • Control bleeding • Decompress cranium, pericardium, thorax, abdomen and limbs • Decontaminate wounds and ruptured viscera • Splint fractures • Cast, traction, pelvic binder, ex-fix • Get back to ITU environment ASAP • Definitive surgery performed several days later
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  • 9. SIRS 1983 SYSTEMIC IMMUNE RESPONSE SYNDROME • Condition characterised by systemic inflammation, organ dysfunction, and organ failure. • Subset of cytokine storm, abnormal regulation of various cytokines • Inflammatory response to sepsis, trauma, hypoperfusion
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  • 11. CARS 1996 COMPENSATORY ANTI-INFLAMMATORY RESPONSE SYNDROME • CARS - systemic deactivation of the immune system tasked with restoring homeostasis from an inflammatory state • More than just cessation of SIRS Bone RC. Sir Isaac Newton, sepsis, SIRS, and CARS. Crit Care Med. 1996;24(7):1125–8
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  • 13. THE ‘FIRST HIT’ Threshold for fatal inflammatory response DEATH: from multiorgan failure or adult respiratory distress syndrome 1st Hit: the trauma inflammatory response time The ‘natural’ systemic inflammatory response
  • 14. THE ‘SECOND HIT’ Threshold for fatal inflammatory response 1st Hit: the trauma inflammatory response time 2nd Hit: the surgery The exaggerated response brought about by the 2nd hit of surgery
  • 15. THE ‘SECOND HIT’ Threshold for fatal inflammatory response 1st Hit: the trauma inflammatory response time 2nd Hit: the surgery In some individuals the lengthy surgery of early total care exacerbates the the systemic inflammatory response resulting in death
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  • 19. POLYTRAUMA • Defined as “a clinical state following injury to the body leading to profound physiometabolic changes involving multisystem’’. • Patient with anyone of the following combination of injuries TWO MAJOR SYSTEM INJURY + ONE MAJOR LIMB INJURY. ONE MAJOR SYSTEM INJURY + TWO MAJOR LIMB INJURY. ONE MAJOR SYSTEM INJURY + ONE OPEN GRADE III SKELETAL INJURY. UNSTABLE PELVIS FRACTURE WITH ASSOCIATED VISCERAL INJURY.
  • 20. • The term “polytrauma” has been frequently defined in terms of a high Injury Severity Score • The internationally accepted threshold of an ISS 16 is based on the description as being predictive of a mortality risk above 10% . Boyd, C.R.; Tolson, M.A.; Copes,W.S. Evaluating trauma care: The TRISS method. Trauma Score and the Injury Severity Score. J. Trauma 1987, 27, 370–378. [CrossRef] [PubMed]
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  • 28. PATIENTS FOR DC SURGERY • 4 groups of patients • Stable: go for Early Total Care • Borderline: ? • Unstable: go for Damage Control Surgery • Extremis: Damage Control Surgery or ITU • Borderline patients are more difficult to define
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  • 32. TIMING OF RETURN AFTER DC SURGERY • Days 2-5 are not safe • During this period: • Marked inflammatory response ongoing • Increased capillary permeability leads to generalized oedema • Cardiac output is high • Patient is fragile • A 2nd hit at this stage could be fatal • Pape et al: prospective study – • multiply injured patients undergoing surgery between days 2 and 4 had a significantly increased inflammatory response compared with patients operated on between days 6 and 8
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  • 40. JTO; Volume 02 / Issue 02 / May 2014
  • 41. EAP • Early Appropriate Care • Acceptance different patients respond differently to first and second hits • Consider severity of initial injury • Consider response to resuscitation • What further surgery required • Continued re assessment and ability to change from ETO TO DCO
  • 42. 20 YO, MALE 01/02/06 – 15:48 • #BOS • #Nasal bone • APC pelvic injury • # R Supracondylar femur • # R Tibia shaft (open) • # L Tibial plateau (open) • # Bimalleolar L ankle
  • 43. PRE HOSPITAL • Intubated • Pre hospital arrest • Hr 144, Systolic 60 • GCS 3
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  • 46. • External fixator • Pelvis • R leg • L leg • Debridement washout, fasciotomy and vac dressing • R thigh • R lower leg • L lower leg • Laparotomy 4 HRS
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  • 48. • Plating pubic symphysis • Intramedullary nail • R femur retrograde • R tibia • Change of Vacs Day 6
  • 49. • ORIF L Tibial plateau • ORIF L fibula • Free Flap R tibia • Rotation flap L Tibia Day 9
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  • 52. SUMMARY • Multiply injured patients may have a profound and life-threatening inflammatory response • A ‘second hit’ of long definitive surgery can result in a fatal inflammatory response • The second hit can be avoided using early ‘damage control surgery’ followed by late ‘definitive care’