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Dr.Vikram Patil
JSS Medical College, JSS AHER
Mysuru
COVID19: RADIOLOGICAL MANIFESTATIONS
MORE THAN MEETS THE EYE
COVID-19:
SINGLE PATHOPHYSIOLOGY,MULTIPLE MANIFESTATIONS
Initial reports of SARS-CoV-2 infection pointed to a highly transmissible pneumonia,
Extensive clinical experience and research have demonstrated that COVID-19 is actually a complex
multisystem disorder.
On a molecular level, infection via the ACE2 receptor initiates a cascade of cell signaling events
resulting in generation of inflammatory cytokines, prothrombotic molecules, and acute phase reactants
These serve to both amplify the immune system’s response as well as damage the surrounding tissue.
Clinical and radiographic findings are the macroscopic manifestations of these microscopic findings:
• Edema secondary to increased tissue permeability and immune cell response,
• Micro and macrothrombi with distal ischemia, and
• Tissue inflammation.
CARDIOTHORACIC:
• Clinical Manifestations:
• Cough
• Dyspnea
• Sore Throat
• Rhinorrhea
• Chest pain
GROUND GLASS:
CONSOLIDATION:
HALO SIGN:
REVERSE HALO SIGN:
CRAZY PAVING:
CONSOLIDATIVE OPACITIES WITH ROUNDED MORPHOLOGY
CAVITATION:
FIBROSIS:
BRONCHIECTASIS:
CYSTIC LUNG DISEASE:
RSNA CONSENSUS STATEMENT
STAGES:
PNEUMOTHORAX:
PNEUMOMEDIASTINUM:
ARDS:
PULMONARY EMBOLISM:
PET-CT:
RESOLUTION:
• DAY 9 DAY 46 DAY 160
MYOCARDIAL INFARCTION:
MYOCARDITIS:
VENTRICULAR THROMBUS:
NEUROLOGIC/ NEUROVASCULAR
• Clinical Manifestations
• Altered Mental status
• Anosmia
• Lethargy
• Stroke
• Confusion
• Paresthesia
• Aphasia
• Amnesia
ACUTE INFARCT:
DENSE MCA:
B/L MCA INFARCT WITH ICA OBSTRUCTION:
MICROBLEED:
CVT:
HEMORRHAGIC VENOUS INFARCT:
ACUTE SUBDURAL HEMORRHAGE:
OLFACTORY LOBE CHANGES:
• Loss of smell
PRES:
LEUKOENCEPHALOPATHY:
ENCEPHALITIS:
VASCULITIS:
GASTROINTESTINAL
• Clinical Manifestations:
• Nausea
• Vomiting
• Diarrhea
• Abdominal pain
GASTRITIS:
COLITIS:
PROCTOLITIS:
PANCREATITIS:
ACUTE CHOLECYTITIS:
HEPATITIS: PERIPORTAL EDEMA
BOWEL OBSTRUCTION:
BOWEL ISCHEMIA:
GENITO-URINARY
• Clinical Manifestations
• Elevated Creatinine
• Proteinuria
• Hematuria
• Hyperkalemia:
RAISED ECHOES:
RENAL INFARCTION:
BLADDER HEMORRHAGE:
VASCULAR:
• Clinical Manifestations
• Edema
• Pulselesness
• Pallor
• Skin changes
• Necrosis
ARTERIAL THROMBUS:
VENOUS THROMBUS:
DVT:
OVARIAN VEIN THROMBUS:
ARTERIAL THROMBUS:
SPLENIC INFARCT:
RHABDOMYOLYSIS:
NEW QUESTIONS ….
HYPOXIC ISCHEMIC ENCEPHALOPATHY:
NEONATE
POST VACCINATION:
ARTIFICIAL INTELLIGENCE:
FUNGAL SINUSITIS:
• POST COVID RECOVERY
• MUCORMYCOSIS
CONTRAST ENHANCEMENT:
MANY UNANSWERED QUESTIONS??????
Covid-19 Radiological Manifestations
Covid-19 Radiological Manifestations

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