enuresis involves the inability to awaken from sleep in response to a voiding stimulus (i.e., a full bladder), coupled with excessive nighttime urine production or decreased functional capacity of the bladder
Hydrocephalus
introduction
Hydrocephalus, also known years ago as “water on the brain”, is a condition where the circulation system of the body’s cerebrospinal fluid (CSF) is not functioning properly. The CSF accumulates in the brain and causes intracranial pressure. A shunt is usually placed to equalize the flow of CSF, which requires surgery. The diagnosis and surgery can be very frightening for the parents as well as the child
definition
Hydrocephalus is a condition characterized by an excess of cerebrospinal fluid (CSF) within the ventricular and subarachnoid spaces of the cranial cavity
INCIDENCE
It is found in 1-3 of every 1000 born children in world wide
Classification
Non communicating. In the non communicating type of congenital hydrocephalus, an obstruction occurs in the free circulation of CSF.
Communicating. In the communicating type of hydrocephalus, no obstruction of the free flow of the CSF exists between the ventricles and the spinal theca; rather, the condition is caused by defective absorption of CSF, thus causing increased pressure on the brain or spinal cord.
CAUSES
Obstruction. The most common problem is a partial obstruction of the normal flow of CSF, either from one ventricle to another or from the ventricles to other spaces around the brain.
Poor absorption. Less common is a problem with the mechanisms that enable the blood vessels to absorb CSF; this is often related to inflammation of brain tissues from disease or injury.
Overproduction. Rarely, the mechanisms for producing CSF create more than normal and more quickly than it can be absorbed.
PATHOPHYSIOLOGY
CLINICAL MANIFESTATION
Poor feeding. The infant with hydrocephalus has trouble in feeding due to the difficulty of his condition.
Large head. An excessively large head at birth is suggestive of hydrocephalus.
Bulging of the anterior fontanelles. The anterior fontanelle becomes tense and bulging, the skull enlarges in all diameters, and the scalp becomes shiny and its veins dilate.
Setting sun sign. If pressure continues to increase without intervention, the eyes appear to be pushed downward slightly with the sclera visible above the iris- the so-called setting sun sign.
High-pitched cry. The intracranial pressure may increase and the infant’s cry could become high-pitched.
Irritability. Irritability is also caused by an increase in the intracranial pressure.
Projectile vomiting. An increase in the intracranial pressure can cause projectile vomiting
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conclusions
Seizures are episodes of abnormal motor, sensory, autonomic, or psychic activity (or a combination of these) resulting from sudden excessive discharge from cerebral neurons.
Every year more than 10 million children die in developing countries due to acute respiratory infections (mostly pneumonia), diarrhea, measles, malaria, or malnutrition - and often to a combination of these illnesses. In 1990s, the WHO, in collaboration with UNICEF and many other agencies, institutions and individuals, responded to this challenge by developing a strategy known as the Integrated Management of Childhood Illness (IMNCI).This strategy adopted in India as Integrated Management of Neonatal and Childhood Illness (IMNCI). IMNCI caters to two groups of children
• 0-2 months, referred to as young infants.
• 2 months to 5 years, referred to as children.
Pica is explained in very simple wording and style by the help of a scenario. Easy to remember and present due to interesting pictures. Helpful for medical students, parents having child with pica and knowledge seekers.
enuresis involves the inability to awaken from sleep in response to a voiding stimulus (i.e., a full bladder), coupled with excessive nighttime urine production or decreased functional capacity of the bladder
Hydrocephalus
introduction
Hydrocephalus, also known years ago as “water on the brain”, is a condition where the circulation system of the body’s cerebrospinal fluid (CSF) is not functioning properly. The CSF accumulates in the brain and causes intracranial pressure. A shunt is usually placed to equalize the flow of CSF, which requires surgery. The diagnosis and surgery can be very frightening for the parents as well as the child
definition
Hydrocephalus is a condition characterized by an excess of cerebrospinal fluid (CSF) within the ventricular and subarachnoid spaces of the cranial cavity
INCIDENCE
It is found in 1-3 of every 1000 born children in world wide
Classification
Non communicating. In the non communicating type of congenital hydrocephalus, an obstruction occurs in the free circulation of CSF.
Communicating. In the communicating type of hydrocephalus, no obstruction of the free flow of the CSF exists between the ventricles and the spinal theca; rather, the condition is caused by defective absorption of CSF, thus causing increased pressure on the brain or spinal cord.
CAUSES
Obstruction. The most common problem is a partial obstruction of the normal flow of CSF, either from one ventricle to another or from the ventricles to other spaces around the brain.
Poor absorption. Less common is a problem with the mechanisms that enable the blood vessels to absorb CSF; this is often related to inflammation of brain tissues from disease or injury.
Overproduction. Rarely, the mechanisms for producing CSF create more than normal and more quickly than it can be absorbed.
PATHOPHYSIOLOGY
CLINICAL MANIFESTATION
Poor feeding. The infant with hydrocephalus has trouble in feeding due to the difficulty of his condition.
Large head. An excessively large head at birth is suggestive of hydrocephalus.
Bulging of the anterior fontanelles. The anterior fontanelle becomes tense and bulging, the skull enlarges in all diameters, and the scalp becomes shiny and its veins dilate.
Setting sun sign. If pressure continues to increase without intervention, the eyes appear to be pushed downward slightly with the sclera visible above the iris- the so-called setting sun sign.
High-pitched cry. The intracranial pressure may increase and the infant’s cry could become high-pitched.
Irritability. Irritability is also caused by an increase in the intracranial pressure.
Projectile vomiting. An increase in the intracranial pressure can cause projectile vomiting
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,
,
,
,
,
,
,
,
,
,
conclusions
Seizures are episodes of abnormal motor, sensory, autonomic, or psychic activity (or a combination of these) resulting from sudden excessive discharge from cerebral neurons.
Every year more than 10 million children die in developing countries due to acute respiratory infections (mostly pneumonia), diarrhea, measles, malaria, or malnutrition - and often to a combination of these illnesses. In 1990s, the WHO, in collaboration with UNICEF and many other agencies, institutions and individuals, responded to this challenge by developing a strategy known as the Integrated Management of Childhood Illness (IMNCI).This strategy adopted in India as Integrated Management of Neonatal and Childhood Illness (IMNCI). IMNCI caters to two groups of children
• 0-2 months, referred to as young infants.
• 2 months to 5 years, referred to as children.
Pica is explained in very simple wording and style by the help of a scenario. Easy to remember and present due to interesting pictures. Helpful for medical students, parents having child with pica and knowledge seekers.
Seizure disorder is one of the important topic in children and adult also. here i explained the seizure disorder in pediatrics, include all most content for nurses level
complete information for the management and care of patient suffering from epilepsy definition ,classification, types, pathophysiology ,clinical manifestation, diagnostic evaluation, medical management, nursing management, care provided to the patient suffering from epilepsy .
Defecation
Normal defecation begins with movement in the left colon, moving stool toward the anus. When stool reaches the rectum, the distention causes relaxation of the internal sphincter and an awareness of the need to defecate. At the time of defecation, the external sphincter relaxes, and abdominal muscles contract, increasing intrarectal pressure and forcing the stool out
The Valsalva maneuver exerts pressure to expel faeces through a voluntary contraction of the abdominal muscles while maintaining forced expiration against a closed airway. Patients with cardiovascular disease, glaucoma, increased intracranial pressure, or a new surgical wound are at greater risk for cardiac dysrhythmias and elevated blood pressure with the Valsalva maneuver and need to avoid straining to pass the stool.
Normal defecation is painless, resulting in passage of soft, formed stool
CONSTIPATION
Constipation is a symptom, not a disease. Improper diet, reduced fluid intake, lack of exercise, and certain medications can cause constipation. For example, patients receiving opiates for pain after surgery often require a stool softener or laxative to prevent constipation. The signs of constipation include infrequent bowel movements (less than every 3 days), difficulty passing stools, excessive straining, inability to defecate at will, and hard feaces
IMPACTION
Fecal impaction results from unrelieved constipation. It is a collection of hardened feces wedged in the rectum that a person cannot expel. In cases of severe impaction the mass extends up into the sigmoid colon.
DIARRHEA
Diarrhea is an increase in the number of stools and the passage of liquid, unformed feces. It is associated with disorders affecting digestion, absorption, and secretion in the GI tract. Intestinal contents pass through the small and large intestine too quickly to allow for the usual absorption of fluid and nutrients. Irritation within the colon results in increased mucus secretion. As a result, feces become watery, and the patient is unable to control the urge to defecate. Normally an anal bag is safe and effective in long-term treatment of patients with fecal incontinence at home, in hospice, or in the hospital. Fecal incontinence is expensive and a potentially dangerous condition in terms of contamination and risk of skin ulceration
HEMORRHOIDS
Hemorrhoids are dilated, engorged veins in the lining of the rectum. They are either external or internal.
FLATULENCE
As gas accumulates in the lumen of the intestines, the bowel wall stretches and distends (flatulence). It is a common cause of abdominal fullness, pain, and cramping. Normally intestinal gas escapes through the mouth (belching) or the anus (passing of flatus)
FECAL INCONTINENCE
Fecal incontinence is the inability to control passage of feces and gas from the anus. Incontinence harms a patient’s body image
PREPARATION AND GIVING OF LAXATIVESACCORDING TO POTTER AND PERRY,
An enema is the instillation of a solution into the rectum and sig
R3 Stem Cells and Kidney Repair A New Horizon in Nephrology.pptxR3 Stem Cell
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India Clinical Trials Market: Industry Size and Growth Trends [2030] Analyzed...Kumar Satyam
According to TechSci Research report, "India Clinical Trials Market- By Region, Competition, Forecast & Opportunities, 2030F," the India Clinical Trials Market was valued at USD 2.05 billion in 2024 and is projected to grow at a compound annual growth rate (CAGR) of 8.64% through 2030. The market is driven by a variety of factors, making India an attractive destination for pharmaceutical companies and researchers. India's vast and diverse patient population, cost-effective operational environment, and a large pool of skilled medical professionals contribute significantly to the market's growth. Additionally, increasing government support in streamlining regulations and the growing prevalence of lifestyle diseases further propel the clinical trials market.
Growing Prevalence of Lifestyle Diseases
The rising incidence of lifestyle diseases such as diabetes, cardiovascular diseases, and cancer is a major trend driving the clinical trials market in India. These conditions necessitate the development and testing of new treatment methods, creating a robust demand for clinical trials. The increasing burden of these diseases highlights the need for innovative therapies and underscores the importance of India as a key player in global clinical research.
Medical Technology Tackles New Health Care Demand - Research Report - March 2...pchutichetpong
M Capital Group (“MCG”) predicts that with, against, despite, and even without the global pandemic, the medical technology (MedTech) industry shows signs of continuous healthy growth, driven by smaller, faster, and cheaper devices, growing demand for home-based applications, technological innovation, strategic acquisitions, investments, and SPAC listings. MCG predicts that this should reflects itself in annual growth of over 6%, well beyond 2028.
According to Chris Mouchabhani, Managing Partner at M Capital Group, “Despite all economic scenarios that one may consider, beyond overall economic shocks, medical technology should remain one of the most promising and robust sectors over the short to medium term and well beyond 2028.”
There is a movement towards home-based care for the elderly, next generation scanning and MRI devices, wearable technology, artificial intelligence incorporation, and online connectivity. Experts also see a focus on predictive, preventive, personalized, participatory, and precision medicine, with rising levels of integration of home care and technological innovation.
The average cost of treatment has been rising across the board, creating additional financial burdens to governments, healthcare providers and insurance companies. According to MCG, cost-per-inpatient-stay in the United States alone rose on average annually by over 13% between 2014 to 2021, leading MedTech to focus research efforts on optimized medical equipment at lower price points, whilst emphasizing portability and ease of use. Namely, 46% of the 1,008 medical technology companies in the 2021 MedTech Innovator (“MTI”) database are focusing on prevention, wellness, detection, or diagnosis, signaling a clear push for preventive care to also tackle costs.
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QA Paediatric dentistry department, Hospital Melaka 2020Azreen Aj
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2. DEFINITION
Convulsion is the involuntary
contraction or series of contractions
of voluntary muscles. It occurs due
to disturbances of the brain
functions resulting from abnormal
excessive electrical discharges from
brain.
4. 3. Infant and young children –
Febrile convulsion
CNS infections
Post infectious & post vaccinal
encephalopathy.
Metabolic disturbances.
Traumatic
Intracranial space occupying lesions.
Drugs and poisons.
Idiopathic epilepsy
5. FEBRILE SEIZURE
Febrile convulsion refers to the
seizures associated with fever but
excluding those related to CNS
infections. It is the commonest cause
of convulsions in early childhood. It is
related to abrupt increase in body
temperature rather than degree of
temperature.
6. TYPES -
1. Typical febrile seizure –
These are generalized than focal and last
less than 10 mins. It is usually found in
children between 6 months to 5 years of
age.
The fits occur within 24 hours of onset of
fever and usually single per febrile episode.
There is no reoccurrence between 12 – 18
hours of attack.
CSF study and EEG are normal after attack.
7. CAUSES -
Family history of convulsion usually
present.
Higher incidence occurs in twins and
children of consanguineous parents.
The condition may have genetic
predisposition or may be due to
immature neuronal membrane response
to rise to body temperature.
8. 2. Atypical febrile convulsion –
They predispose to idiopathic epilepsy.
The children may have focal convulsion of
more than 20 mins duration even
without significant fever.
There may be abnormal EEG for two
weeks after the attack.
9. MANAGEMENT
Anticonvulsive drugs. Diazepam 0.3mg/kg IV
Phenobarbitol 5mg/kg IM.
Sodium valproate 10 -20 mg/kg/day.
Antipyretics to reduce fever.
Clear airway and administer oxygen if needed.
Hydration and nutritional status to be
maintained by IV solutions.
Rest and comfortable position should be given.
Maintain the personal hygiene.
10. EPILEPSY -
It is recurrent, episodic, paroxysmal
transient disturbances of brain function
due to abnormal electrical activity of
neurons.
it is manifestated as abnormal, motor,
sensory or psychomotor phenomena
and often with impaired or loss of
consciousness.
13. An aura –
A peculiar sensation with dizziness occurs
in about one third epileptic children
before tonic – clonic seizure.
Tonic spasm phase –
Child’s entire body becomes stiff, face
may become pale and distorted, eyes
fixed in one position, back may be
arched, head turned to backward or in
one side, arms are fixed and hands are
clenched.
14. child fall on ground.
Loss of consciousness.
frothy discharge from mouth.
Ineffective breathing and cyanosis.
Weak and irregular pulse.
Duration of this phase is 30 secs.
15. Clonic phase –
it is manifestated with rhythmic jerky
movements due to alternating
contraction of muscle group, which
usually starts from one part and
generalized including face muscle.
The child may pass stool and urine
involuntarily.
May have tongue bite.
Duration is from few minutes to few
hours.
16. Postictal state –
the child is usually become sleepy,
confused or exhausted.
May complaint of headache.
The child may not be able to recall the
episode.
17. Absence seizure (petit mal) –
it rarely appears before 5 years of age.
the child may loss contact with
environment for few seconds.
may appear day dreaming.
may discontinue the activity suddenly.
seizure may present as rolling of eyes,
nodding of head, slight head movement
and smacking of lips.
18. STATUS EPILEPTICUS
It is a state of continuing recurrent
seizure that prolonged for more than 30
minutes or occurs in series without
regaining consciousness in between
attack.
it is a case of medical emergency.
The child may have cardiac arrest.
19. MYOCLONIC
SEIZURE(INFANTILE SPASM)
This seizure occurs in infants usually
between 3 to 8 months of age.
It associated with cerebral hemorrhage
and mental retardations.
The child present with sudden forceful
myoclonic contraction involving muscles
of trunk, neck and extremities.
The duration is less than 1 min.
20. NEONATAL SEIZURE
Neonatal seizure are present as subtle,
multi focal clonic, focal clonic, generalized
tonic and myoclonic types.
Subtle seizure may be present with eye
blinking, fluttering and buccolingual
movement.
21. DIAGNOSIS
History taking and physical examination.
Neurological examination.
CSF test
Blood examination
Urine examination.
EEG, CT scan, MRI
22. MANAGEMENT -
Management is depends on identified
cause.
Management mainly done with –
drug therapy
Diet therapy
Surgical management
23. DRUG THERAPY -
Antiepileptic drugs –
Phenobarbital – 3 to 5 mg/kg/day.
Diphenylhydantoin – 5 to 8 mg/kg/day.
Carbamazepine – 10 to 20 mg/kg/day
Diazepan – 0.2 mg/kg/dose IV
Sodium valproate – 15 to 20 mg/kg/day
Ethosuximide – 10 to 20 mg/kg/day
24. DIET THERAPY -
Ketogenic diet given to raise the seizure
threshold with calculated amount of
proteins and fats without carbohydrates.
This child should not given IV fluid with
dextrose.
26. NURSING DIAGNOSIS -
Risk for injury related to convulsion
episode.
Ineffective breathing related to spasm of
respiratory muscles.
Soicial isolation related to misconception.
Altered self esteem related to lack of
control over seizure.
Knowledge deficit related to long term
care.