Hypertrophic pyloric stenosis is a condition in infants where the muscle surrounding the pylorus (opening from the stomach to the small intestine) thickens, causing projectile vomiting after feeding. It most often affects young babies, especially boys. Surgery to cut the thickened pyloric muscle (pyloromyotomy) corrects the problem and stops the vomiting. With proper pre- and post-operative care including IV fluids, feeding, monitoring for complications, infants usually recover well after surgery.