1) Closed-chest cardiac massage is an effective technique for maintaining circulation and oxygenation of the heart and brain during cardiac arrest, without requiring opening of the chest.
2) The technique involves rhythmic external compression of the sternum to squeeze blood out of the heart, and was successful in resuscitating 20 cardiac arrest patients with a 70% survival rate and no neurological deficits.
3) Case reports demonstrate the technique successfully resuscitating patients from cardiac standstill during anesthesia induction and surgery, with no long-term effects.
It is a heart valve situated between the left ventricle and the aorta.
The valve regulates the oxygenated blood being pumped to the rest of the body from the left ventricle.
Conditions like aortic valve stenosis may hamper the valve function.
Evaluation of Mixed Valvular Heart Disease on Echossuser1fdca4
Multiple valvular disease is the combination of regurgitant or stenotic lesions on more than one cardiac valve. Mixed valve disease occurs in the presence of stenotic and regurgitant lesions on the same valve. These conditions are very prevalent and impose particular challenges for both the assessment of the severity of valvular lesions and decisions regarding treatment allocation. This presentation discusses the evaluation of patients with multiple concomitant valvular heart disease pathologies and key findings on echocardiography. It also reviews reviews pathology and treatment of multiple valvular disease.
It is a heart valve situated between the left ventricle and the aorta.
The valve regulates the oxygenated blood being pumped to the rest of the body from the left ventricle.
Conditions like aortic valve stenosis may hamper the valve function.
Evaluation of Mixed Valvular Heart Disease on Echossuser1fdca4
Multiple valvular disease is the combination of regurgitant or stenotic lesions on more than one cardiac valve. Mixed valve disease occurs in the presence of stenotic and regurgitant lesions on the same valve. These conditions are very prevalent and impose particular challenges for both the assessment of the severity of valvular lesions and decisions regarding treatment allocation. This presentation discusses the evaluation of patients with multiple concomitant valvular heart disease pathologies and key findings on echocardiography. It also reviews reviews pathology and treatment of multiple valvular disease.
The technique of pulmonary resection had dramatically changed from mass ligation of pulmonary hilum to individual ligation of hilar structures and recently to video-assisted thoracoscopic pulmonary resection. However, the safe performance of lung resection requires a perfect knowledge of hilar anatomy and a technique with which the surgeon is familiar.
Repolarization ST wave Abnormalities
Precise guide for Allied Health Science Students especially cardiac specialty students, DGNM, B.Sc Nursing & M.Sc Nursing Students regarding Repolarization ST wave Abnormalities.
cardiac arrest is the sudden cessation of heart beat and normal cardiac function resulting in loss of effective circulation. cardiopulmonary resuscitation (CPR) is the immediate first aid treatment in case of a cardiac arrest. CPR has to be initiated within 10 seconds after cardiac arrest. cardiac arrest can be determined by palpating for carotid pulse. carotid pulse is absent in case of cardiac arrest.
A treadmill exercise stress test is used to determine the effects of exercise on the heart. Exercise allows doctors to detect abnormal heart rhythms (arrhythmias) and diagnose the presence or absence of coronary artery disease.
This test involves walking in place on a treadmill while monitoring the electrical activity of your heart. Throughout the test, the speed and incline of the treadmill increase. The results show how well your heart responds to the stress of different levels of exercise.
Description
A technologist will explain the test to you, take a brief medical history, and answer any questions you may have. Your blood pressure, heart rate, and electrocardiogram (ECG) will be monitored before, during, and after the test.
You will be asked to sign a consent form. This form is required before the test can proceed.
You will be asked to remove all upper body clothing, and to put on a gown with the opening to the front.
Adhesive electrodes will be put onto your chest to capture an ECG. The sites where the electrodes are placed will be cleaned with alcohol and shaved if necessary. A mild abrasion may also be used to ensure a good quality ECG recording.
Your resting blood pressure, heart rate, and ECG will be recorded.
You will be asked to walk on a treadmill. The walk starts off slowly, then the speed and incline increases at set times. It is very important that you walk as long as possible because the test is effort-dependent.
You will be monitored throughout the test. If a problem occurs, the technologist will stop the test right away. It is very important for you to tell the technologist if you experience any symptoms, such as chest pain, dizziness, unusual shortness of breath, or extreme fatigue.
Following the test, you will be asked to lie down. Your blood pressure, heart rate, and ECG will be monitored for three to five minutes after exercise.
The data will be reviewed by a cardiologist after the test is completed. A report will be sent to the doctor(s) involved in your care.
coronary artery bypass graft surgery CABGSunil kumar
coronary artery bypass graft surgery, explanation of CABG on-pump and off-pump procedures, physiotherapy management after surgery. indications of CABG. description of the procedure, investigations before surgery, per operative and post operative management
The technique of pulmonary resection had dramatically changed from mass ligation of pulmonary hilum to individual ligation of hilar structures and recently to video-assisted thoracoscopic pulmonary resection. However, the safe performance of lung resection requires a perfect knowledge of hilar anatomy and a technique with which the surgeon is familiar.
Repolarization ST wave Abnormalities
Precise guide for Allied Health Science Students especially cardiac specialty students, DGNM, B.Sc Nursing & M.Sc Nursing Students regarding Repolarization ST wave Abnormalities.
cardiac arrest is the sudden cessation of heart beat and normal cardiac function resulting in loss of effective circulation. cardiopulmonary resuscitation (CPR) is the immediate first aid treatment in case of a cardiac arrest. CPR has to be initiated within 10 seconds after cardiac arrest. cardiac arrest can be determined by palpating for carotid pulse. carotid pulse is absent in case of cardiac arrest.
A treadmill exercise stress test is used to determine the effects of exercise on the heart. Exercise allows doctors to detect abnormal heart rhythms (arrhythmias) and diagnose the presence or absence of coronary artery disease.
This test involves walking in place on a treadmill while monitoring the electrical activity of your heart. Throughout the test, the speed and incline of the treadmill increase. The results show how well your heart responds to the stress of different levels of exercise.
Description
A technologist will explain the test to you, take a brief medical history, and answer any questions you may have. Your blood pressure, heart rate, and electrocardiogram (ECG) will be monitored before, during, and after the test.
You will be asked to sign a consent form. This form is required before the test can proceed.
You will be asked to remove all upper body clothing, and to put on a gown with the opening to the front.
Adhesive electrodes will be put onto your chest to capture an ECG. The sites where the electrodes are placed will be cleaned with alcohol and shaved if necessary. A mild abrasion may also be used to ensure a good quality ECG recording.
Your resting blood pressure, heart rate, and ECG will be recorded.
You will be asked to walk on a treadmill. The walk starts off slowly, then the speed and incline increases at set times. It is very important that you walk as long as possible because the test is effort-dependent.
You will be monitored throughout the test. If a problem occurs, the technologist will stop the test right away. It is very important for you to tell the technologist if you experience any symptoms, such as chest pain, dizziness, unusual shortness of breath, or extreme fatigue.
Following the test, you will be asked to lie down. Your blood pressure, heart rate, and ECG will be monitored for three to five minutes after exercise.
The data will be reviewed by a cardiologist after the test is completed. A report will be sent to the doctor(s) involved in your care.
coronary artery bypass graft surgery CABGSunil kumar
coronary artery bypass graft surgery, explanation of CABG on-pump and off-pump procedures, physiotherapy management after surgery. indications of CABG. description of the procedure, investigations before surgery, per operative and post operative management
If You Build It, Will They Come? - How to Increase Learning AdoptionB.J. Schone
Designing and building learning materials is a tough enough job, but what happens when you spend weeks or months on a project and nobody even bothers to use it? This presentation will explore more than a dozen ideas for increasing user adoption of learning materials through a series of strategies and tactics you can begin using immediately.
Increasing user adoption requires an in-depth understanding of your users, including their jobs, behaviors, wants, and needs. Once you understand these elements, you can design your implementation approach and introduce on-going activities to increase adoption.
In this presentation, we will explore the psychology of the user, the intent of the organization, and the actions you can take as a learning professional to drive adoption and improve the performance of your users.
RAE-Revista de Administração de Empresas, foi lançada em maio de 1961, com perfil acadêmico-científico, dedicada a professores, pesquisadores e estudantes. É o mais tradicional periódico acadêmico-científico de administração no Brasil, com publicação ininterrupta desde seu lançamento. Acesse: www.fgv.br/rae
Personally designed (content + graphics design), officially accredited REQB® - Foundation Level Requirements Manager courseware.
Trademarks are properties of the holders, who are not affiliated with courseware author.
Performance appraisal problems and solutionszonaharper2
In this file, you can ref useful information about performance appraisal problems and solutions such as performance appraisal problems and solutions methods, performance appraisal problems and solutions tips, performance appraisal problems and solutions forms, performance appraisal problems and solutions phrases … If you need more assistant for performance appraisal problems and solutions, please leave your comment at the end of file.
Cardiopulmonary resuscitation (CPR) is an emergency procedure that combines chest compressions often with artificial ventilation in an effort to manually preserve intact brain function until further measures are taken to restore spontaneous blood circulation and breathing in a person who is in cardiac arrest.
Cardiopulmonary resuscitation (CPR) is an emergency procedure that combines chest compressions often with artificial ventilation in an effort to manually preserve intact brain function until further measures are taken to restore spontaneous blood circulation and breathing in a person who is in cardiac arrest.
Advanced Trauma Life Support : Part 1 - Basic Life SupportMayank Jain
For medical students, pg residents, nursing students, and other medical professionals. Contains medical jargon and advice, not for use by general public. For use only under a trained instructor.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
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CLOSED-CHEST CARDIAC MASSAGE
1. CLOSED-CHEST CARDIAC MASSAGE
W. B. Kouwenhoven, Dr. Ing., James R. Jude, M.D.
and
G. Guy Knickerbocker, M.S.E., Baltimore
When cardiac arrest occurs, either as standstill
or as ventricular fibrillation, the circulation must
be restored promptly; otherwise anoxia will result Cardiac resuscitation after cardiac arrest
in irreversible damage. There are two techniques or ventricular fibrillation has been limited by
that may be used to meet the emergency: one is to the need for open thoracotomy and direct
open the chest and massage the heart directly and cardiac massage. As a result of exhaustive
the other is to accomplish the same end by a new animal experimentation a method of external
method of closed-chest cardiac massage. The latter transthoracic cardiac massage has been de-
method is described in this communication. The veloped. Immediate resuscitative measures
closed-chest alternating current defibrillator ' that can now be initiated to give not only mouthx=req--
was developed in our laboratories has proved to be to-nose artificial respiration but also ade-
an effective and reliable means of arresting ven¬ quate cardiac massage without thoracotomy.
tricular fibrillation. Its counter-shock must be sent The use of this technique on 20 patients has
through the chest promptly, or else cardiac anoxia given an over-all permanent survival rate of
will have developed to such a degree that the heart 70%. Anyone, anywhere, can now initiate
will no longer be able to resume forceable contrac¬ cardiac resuscitative procedures. All that is
tions without assistance. Our experience has indi¬ needed are two hands.
cated that external defibrillation is not likely to be
followed by the return of spontaneous heart action,
unless the counter-shock is applied within less than
three minutes after the onset of ventricular fibrilla¬ one-half minutes after the onset of induced ven¬
tion. tricular fibrillation. They reported that this time
A study was undertaken of means of extending limitation might be extended to as long as eight
this time limitation without opening the chest. A minutes by rhythmical application of pressure on
method was sought that would provide adequate the thorax in the region of the heart. In tests which
circulation to maintain the tone of the heart and the lasted 10 to 15 minutes 19 animals survived and 17
nourishment of the central nervous system. This died. These authors, however, gave no specific
method was to be at once readily applicable, safe information as to the method of application of the
to use, and requiring a minimum of gadgets. pressure. Rainer and Bullough7 treated cardiac
One of the first attempts at enhancing circulation arrest in children by lowering the head about 10
in the arrested heart was a closed-chest method degrees, placing one arm underneath the patient's
reported by Boehm in 1878. Working with cats,
2 knees, and flexing the legs and buttocks against the
he grasped the chest in his hands at the area of chest. They reported eight successful resuscitations
in patients ranging from 8 weeks to 13 years in age.
greatest expansion and applied rhythmic pressure.
His results were quite striking in some series of Stout 8 in 1957 reported the successful use of this
tests. Tournade and co-workers reported that by
3 method in one adult.
an abrupt compression of the thorax of a dog in
Experiment
cardiac arrest blood pressures of 60 to 100 mm. Hg
With dogs used as the experimental animal, car¬
could be produced. No survival studies were given.
Killick and Eve reported that the rocking tech¬
4 diac arrest in the form of ventricular fibrillation
was induced. In the initial experiments more than
nique of artificial respiration, by which a patient is 100 dogs, weighing from 5 to 24 kg. (11 to 52
tilted about 60 degrees in each direction from the
horizontal plane, will produce a change in the lb.), were used in testing various methods of mov¬
blood pressure at the atrium from 38 to 76 mm. Hg. ing blood by massaging the intact chest. A safe and
Eve 5 hypothesized that this change will produce
effective method of "massaging the heart" without
sufficient blood flow to nourish the heart and the thoracotomy was developed. Adequate circulation
for periods as long as 30 minutes was easily main¬
brain. In 1947 Gurvich and Yuniev 6 found that a
tained with the dog in ventricular fibrillation. A
capacitor discharge sent through the chest of a dog closed-chest defibrillating shock would result in
would be followed by a resumption of the cardiac the immediate return of normal sinus rhythm in
function if applied not later than one or one and such animals.
In fig. 1 are shown sections taken from the re¬
Lecturer in Surgery (Dr. Kouwenhoven), Resident Surgeon (Dr.
Jude), and Assistant in Surgery (Mr. Knickerbocker), Johns Hopkins
cording of the variations in blood flow, blood pres¬
University School of Medicine. sure, and electrocardiogram of a dog whose heart
Downloaded from www.jama.com by guest on November 10, 2010
2. was in ventricular fibrillation for eight minutes. slightly to permit full expansion of the chest. The
Simultaneously recorded on a four-channel recorder operator should be so positioned that he can use
were the blood flow in a carotid artery, the instan¬ his body weight in applying the pressure. Sufficient
taneous and average pressures in a femoral artery, pressure should be used to move the sternum 3 or
and the cardiogram. The tracings in the first column 4 cm. toward the vertebral column.
of figure 1 are the normal values of these respective Closed-chest cardiac massage provides some ven¬
phenomena immediately before fibrillation was in¬ tilation of the lungs, and if there is only one person
duced by a 110-volt shock. The second column present in a case of arrest, attention should be
shows the build-up of blood flow and pressures that
took place when closed-chest cardiac massage was
started, one minute after the onset of fibrillation.
The third column is a record of what took place
about seven minutes later. Note that vigorous
fibrillation has been maintained throughout the
entire period. The fourth and last column shows
the immediate return of normal sinus rhythm when
the closed chest defibrillator shock was given. The
electrocardiograph was temporarily disconnected
when the counter shock was applied.
Method—The method of closed-chest cardiac
massage developed during these animal studies is
simple to apply; it is one that needs no com¬
plex equipment. Only the human hand is required.
The principle of the method as applied to man is
readily seen by consideration of the anatomy of the
bony thorax and its contained organs. The heart is
limited anteriorly by the sternum and posteriorly
by the vertebral bodies. Its lateral movement is
restricted by the pericardium. Pressure on the
sternum compresses the heart between it and the
spine, forcing out blood. Relaxation of the pressure
allows the heart to fill. The thoracic cage in uncon¬
scious and anesthetized adults is surprisingly mo¬
bile. The method of application is shown in figure
2. With the patient in a supine position, preferably
on a rigid support, the heel of one hand with the
Fig 2.—Position of hands during massage of adult.
concentrated the massage. If there are two or
on
more persons one should massage the
present,
heart while the other gives mouth-to-nose respira¬
tion.
ClinicalApplication.—About nine months prior
to time of at Johns Hopkins Hospital, clin¬
writing,
ical application of closed-chest cardiac massage was
Fig. 1 .—Record of blood flow, pressures, and electrocardio¬ successfully illustrated in a case of cardiac arrest.
gram of dog whose heart was in ventricular fibrillation for Initially, it was felt that the method might be useful
eight minutes. I: normal initial values; II: start of closed- in treating arrest in children, whose ribs are known
chest massage; III: seventh minute of massage; IV: closed- to be flexible, but that it would not be effective in
chest defibrillation. adults. This latter assumption was proved to be in¬
correct, since the chest of an unconscious adult was
other on top of it is placed on the sternum just found to be remarkably flexible.
cephalad to the xiphoid. Firm pressure is applied During the 10 months prior to writing this meth¬
vertically downward about 60 times per minute. At od alone has been applied on 20 patients aged from
the end of each pressure stroke the hands are lifted 2 months to 80 years. In 13 of these patients artifi-
Downloaded from www.jama.com by guest on November 10, 2010
3. cial respiration was applied simultaneously with the Nov. 17,1959, the patient was again returned to the
massage; the duration of the massage varied from operating room for a left mastoidectomy, after
less than 1 minute to 65 minutes. In seven cases preoperative medication with 60 mg. of pentobarbi-
records were obtained of either the blood pressure tal and 0.25 mg. of scopolamine. The patient
or of the electrical activity of the heart (by electro¬ was yomiting continuously on arrival in the anes¬
cardiogram) during the episode. Systolic pressures thesia room, and his pulse was irregular. The induc¬
tion of anesthesia stormy because of the pa¬
was
tient's nausea. He given open-drop anesthesia
was
mm Hg with fluothane and intubation was performed with
120- ease. At this point his pulse suddenly disappeared,
80- as did the blood pressure and
apical beat. Closed-
40-
AJVJVJUVÀjy. chest cardiac massage was carried out for one
minute and the patient responded with a good
return of pulse, blood pressure, and respirations.
Fig. 3.—Blood pressure produced in an adult by closed-
chest cardiac massage. The operation was canceled, and the patient re¬
turned to the ward. He had no further difficulties
during massage ranged from 60 to 100 mm. Hg. and no central nervous system damage.
Figure 3 shows the blood pressures recorded on an Case 3.—An 80-year-old woman was admitted
adult. The hearts of 3 of the 20 patients treated with a large tumor of the thyroid and had a
were in ventricular fibrillation, and all were de- tracheostomy with biopsy of the thyroid on Nov. 5,
fibrillated by a closed-chest A. C. deffbrillator 1959. The diagnosis was papillary adenocarcinoma
shock. All 20 patients were resuscitated and, at time of the thyroid. She was returned to the operating
of writing, 14 of them are alive without central room three days later for a definitive procedure
nervous system damage and without undergoing after premedication with 100 mg. of pentobarbital
thoracotomy. and 0.5 mg. of atropine. She was given anesthesia
Report of Cases with thiopental sodium and fluothane. Succinylcho-
line in divided doses was also given. Intubation
Four cases of cardiac standstill and one case of
was performed through the tracheostomy. A few
ventricular fibrillation are reported below.
minutes thereafter the blood pressure became un¬
Case L—A 35-year-old woman was admitted in
obtainable and the administration of fluothane was
July, 1959, through the emergency room, with acute immediately stopped. There was no apical or peri¬
cholecystitis. After premedieation with 8 mg. of mor¬
phine sulfate, 0.4 mg. of atropine, and 100 mg. of pheral pulse. External cardiac massage was begun
pentobarbital (Nembutal), she was taken, one and immediately and carried out for a period of two
one-half hours later, to the operating room where minutes. Mephentermine (Wyamine), 30 mg., and
anesthesia was induced with thiopental sodium and phenylephrine (Neo-Synephrine) hydrochloride, 1
succinylcholine. Intubation was attempted, but diffi¬ mg., were given intravenously. A good pulse and
culty was encountered, with inability to ventilate the
patient. She became pulseless and cyanotic and her
respirations disappeared. External cardiac massage
was instituted, without artificial respiration. After
two minutes a strong transthoracic pulse developed,
together with spontaneous shallow respirations.
Blood pressure returned to 130/80 mm. Hg and
pulse to 100 beats per minute. Intubation pro¬
ceeded thereafter, with some difficulty but no fur¬
ther cardiac problems. The patient underwent a
cholecystectomy for acute hydrops of the gallblad¬
der and had anuneventful recovery. She was dis¬
charged five days later
without neurological signs
or symptoms and has been entirely normal on sub¬
sequent follow-up examinations.
Case 2.—A 9-year-old boy with chronic mastoidi-
tis was admitted and on Nov. 5, 1959, had a mas-
Fig. 4 (case 5).—First defibrillation shock, followed by
toidectomy. Postoperatively the patient was very standstill and return of fibrillation.
cyanotic. Respirations stopped in the recovery room
but a weak heart beat was obtainable. The child blood pressure returned about 90 seconds after the
was given mouth-to-mouth respiration and cardiac
assistance with external cardiac massage for about
beginning of massage. The operation was com¬
pleted without difficulty and the patient had no
30 seconds. He responded to this with good return sign of central nervous system damage in the post¬
of all functions and had no further difficulty. On operative period.
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4. Case 4.—A 12-year-old boy developed sudden Summary
cardiac arrest Jan. 22, 1960, while undergoing
on
Closed-chest cardiac massage has been proved to
an excision of a verrucus linearis of the scalp.
be effective in cases of cardiac arrest. It has pro¬
Under thiopental and fluothane anesthesia the
vided circulation adequate to maintain the heart
patient became anoxic, with an irregular pulse fol¬ and the central nervous system, and it has provided
lowed by arrest. Local infiltration with epinephrine-
saline solution may have contributed. The pupils
an opportunity to bring a defibrillator to the scene
dilated and the patient was pulseless and without
respiration for at least one minute before external
massage was begun. After one minute of massage a
good pulse and pressure returned. The operation
was completed without difficulty. Postoperatively
the patient had transitory blindness and bilateral
Babinski reflex. Nystagmus was also present. Over
36 hours the neurological findings returned to
normal. The remainder of the postoperative course
was uneventful.
Case 5.—A 45-year-old man was brought to the
emergency room of the hospital with excruciating
substernal chest pains radiating down both arms on
Jan. 6, 1960. He was conscious when admitted.
While removing his clothing, preparatory to exami¬
nation, he fell to the floor. His respirations ceased,
and there were no heart sounds and no pulse. The
house officer immediately began closed-chest car¬
diac massage. An electrocardiogram was taken and
showed the heart to be in ventricular fibrillation.
The patient began to breathe spontaneously. Ten
minutes after the start of external massage artificial Fig. 6 (case 5).—Cardiogram taken two hours after de-
respiration by endotracheal tube was first begun. fibrillation, showing anterior myocardial infarction.
External heart massage and artificial respiration
were continued for 20 minutes, while a closed-chest if necessary. Supportive drug treatment and other
A. C. defibrillator was being brought to the emer¬ measures may be given. The necessity for
a thora¬
gency room. cotomy is eliminated. The real value of the method
Two defibrillator shocks were given; the first lies in the fact that it can be used wherever the
(fig. 4) temporarily arrested the fibrillation. After emergency arises, whether that is in or out of the
the second shock (fig. 5) the heart resumed natural hospital.
beats. An electrocardiographic tracing (fig. 6) taken This study was supported by a grant from the National
two hours later showed an anterior myocardial Heart Institute, National Institutes of Health.
infarction. Subsequent tracings confirmed the diag¬ References
nosis.
1. Kouwenhoven, W. B.; Milnor, W. R.; Knickerbocker,
G. G.; and Chestnut, W. R.: Closed Chest Defibrillation of
Heart, Surgery 42:550-561 (Sept.) 1957.
2. Boehm, R.: V. Arbeiten aus dem pharmakologischen
Institute der Universitl=a"tDorpat: 13. Ueber Wiederbelebung
nach Vergiftungen und Asphyxie, Arch. exper. Path. u. Phar-
makol. 8:68-101, 1878.
3. Tournade, A.; Rocchisani, L.; and Mely, G.: Etude
expl=e'rimentaledes effets circulatoires qu'entrainent la respira-
tion artificielle et la compression saccadl=e'edu thorax chez le
chien Compt. rend. Soc. de biol. 117:1123-1126, 1934.
4. Killick, E. M., and Eve, F. C.: Physiological Investiga-
tion of Rocking Method of Artificial Respiration, Lancet
2:740-742 (Sept. 30) 1933.
5. Eve, F. C.: Artificial Circulation Produced by Rocking:
Its Use in Drowning and Anaesthetic Emergencies, Brit. M. J.
Fig. 5 (case 5).—Second defibrillation shock, followed by 2:295-296 (Aug. 23) 1947.
natural beats. 6. Gurvich, H. L., and Yuniev, G. S.: Restoration of Heart
Rhythm During Fibrillation by Condenser Discharge, Am.
The patient had no sign of central nervous system Rev. Soviet Med. 4:252-256 (Feb.) 1947.
damage, except amnesia for the period of cardiac 7. Rainer, E. H., and Bullough, J.: Respiratory and Car-
diac Arrest During Anesthesia in Children, Brit. M. J. 2:
massage plus two hours. He has followed, without 1024-1028 (Nov. 2) 1957.
incident, the usual course of treatment fer myo¬ 8. Stout, H. A.: Cardiac Arrest: Massage Without Incision,
cardial infarction. J. Oklahoma M. Assoc. 3:112-114 (March) 1957.
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