CHIMERA (Genetics)
Melvin Alex
Hybrid vs Chimera
X
Horse Donkey
Mule
Chimera (Genetics)
A chimera is a mixture of two separate
organisms, with discrete parts of each.
Sheep-Goat Chimeras
Chimeras in mythology
Naturally occurring chimeras are rare,
usually found only in same species
Free martin fetus with conjoined circulation:
The key to understanding immunological tolerance
Fetal-Maternal chimerism in humans
Dr. Lee Nelson
Humanzee
• Human STEM cells are
injected into a chimp
blastocysts
• It will help us to find how cells
grow and interact inside an
animal.
By, Mriganka
Humans and Chimps share a LOT of DNA!
Procedure
Delete
specific
piece of
animal DNA
Inject
embryo with
human
STEM cells
Embryo is
then put
back inside
animal
Applications
• Xenotransplantation
• To understand how our cells grow and interact inside an animal.
• To make functional human tissues
• Immunological tolerance
ETHICAL ISSUES
• Because it involves research on human embryos.
• It disregards the welfare of animals and animal species
involved.
• More specifically, because it disregards the welfare of higher
primates involved.
Conclusion
• “Chimps share 98% of the human genome, and a fully mature chimp
has the equivalent mental abilities and consciousness of a four-year-
old human. Fusing a human and chimpanzee embryo—which
researchers say is feasible—could produce a creature so human that
questions regarding its moral and legal status would throw 4,000
years of ethics into chaos. Would such a creature enjoy human
rights? Would it have to pass some kind of ‘humanness' test to win
its freedom? Would it be forced into doing menial labor or be used to
perform dangerous activities?”

Chimera (genetics)