This document summarizes how organic molecules facilitate chemical reactions. It discusses mechanical and chemical changes, noting that chemical changes rearrange molecular bonds to form new substances and often release or absorb energy. The rate of reactions can be influenced by factors like temperature, pH, and catalysts. Enzymes are organic catalysts that are proteins and facilitate biochemical reactions by lowering the activation energy needed. Enzymes are specific to the reactions they catalyze and work through a lock and key mechanism of binding to substrates.