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CHAPTER 3
Tissues
Principles of
Human Anatomy
13th Edition
Gerard J. Tortora & Mark T. Nielsen
Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.
Four Major Families of Tissues
 Epithelial tissue
 Connective tissue
 Muscular tissue
 Nervous tissue
Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.
Types of Tissues
Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.
Cell Junctions
 Cell junctions
 There are five major types of cell junctions
 Tight junctions
 Adherens junctions
 Desmosomes
 Hemidesmosomes
 Gap junctions
Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.
Cell Junctions
Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.
Comparison Between Epithelial and Connective Tissue
Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.
Epithelial Tissue
 General features
 Cells are arranged in continuous sheets
 Cells have lateral surfaces, apical (free)
surface, and basal surface
Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.
Surface of Epithelial Cells
Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.
Epithelium
 Numerous cell junctions that securely attach
neighboring cells
 Avascular
 High capacity for cell division
 Numerous functions
Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.
CLINICAL CONNECTION
 Papanicolaou test
Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.
Covering and Lining Epithelium
 Arrangement of cells into layers reflects their
location and function
 Simple (unilaminar) epithelium
 Pseudostratified epithelium
 Stratified (multilaminar) epithelium
Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.
Covering and Lining Epithelium
 Cells may be categorized by cell shape
 Squamous
 Cuboidal
 Columnar
 Transitional
Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.
Cell Shapes and Arrangement of Layers
Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.
Types of Epithelial Tissues
 Simple epithelium
 Simple squamous
 Simple cuboidal
 Simple columnar
 Nonciliated
 Ciliated
 Pseudostratified columnar
Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.
Clinical Connection
 Papanicolaou test
Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.
Epithelial Tissues
Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.
Simple Cuboidal
Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.
Nonciliated Simple Columnar Epithelium
Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.
Ciliated Simple Columnar Epithelium
Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.
Pseudostratified Columnar
Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.
Stratified Epithelial Tissues
 Stratified squamous
 Stratified cuboidal
 Stratified columnar
 Transitional
Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.
Stratified Squamous Epithelium
Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.
Stratified Cuboidal Epithelium
Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.
Stratified Columnar Epithelium
Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.
Transitional Epithelium
Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.
Glandular Epithelium
 Specialized epithelial cells organized to form
glands that secrete substances into ducts,
onto a surface, or into the blood
 Endocrine glands
 Exocrine glands
Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.
Endocrine Glands
Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.
Exocrine Glands
 Structurally classified into unicellular and
multicellular glands
Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.
Exocrine Glands
Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.
Glands - Classification: Simple and
Compound
 Simple tubular
 Simple branched tubular
 Simple coiled tubular
 Simple acinar
 Simple branched acinar
 Compound tubular
 Compound acinar
 Compound tubuloacinar
Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.
Multicellular Exocrine Glands
Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.
Functional Classification of Exocrine
Glands
 Merocrine
 Apocrine
 Holocrine
Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.
Functional
Classification of
Multicellular
Exocrine Glands
Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.
Connective Tissue
 Connective tissue is one of the most
abundant and widely distributed tissues in the
body
 Fibroblasts
 Macrophages
 Plasma cells
 Mast cells
 Adipocytes
 White blood cells
Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.
Representative Cells and Fibers in
Connective Tissue
Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.
Connective Tissue Extracellular
Matrix
 Glycosaminoglycans (GAGs)
 Hyaluronic acid
Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.
Fibers Embedded in Extracellular
Matrix
 Collagen
 Elastic
 Reticular
Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.
Connective Tissue
 Embryonic connective tissue
 Mature
 Loose
 Dense
 Cartilage
 Bone
 Liquid
Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.
Clinical Connection
 Marfan syndrome
Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.
Mesenchyme
Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.
Mucous Connective Tissue
Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.
Aerolar Connective Tissue
Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.
Adipose Tissue
Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.
Clinical Connection
 Liposuction
 Cryolipolysis
Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.
Reticular Connective Tissue
Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.
Dense Regular Connective Tissue
Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.
Dense Irregular Connective Tissue
Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.
Elastic Connective Tissue
Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.
Hyaline Cartilage
Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.
Fibrocartilage
Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.
Elastic Cartilage
Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.
Clinical Connection
 Tissue engineering
Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.
Bone Tissue
Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.
Blood – Liquid Connective Tissue
Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.
Membranes
 Epithelial membranes
 Mucous membranes (mucosa)
 Serous membranes (serosa)
 Cutaneous membrane (skin)
 Synovial membranes
Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.
Membranes
Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.
Membranes
Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.
Membranes
Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.
Membranes
Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.
Muscular Tissue
 Muscular tissue consists of cells, usually
called muscle fibers
 There are three major types
 Skeletal
 Cardiac
 Smooth
Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.
Muscular Tissue
Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.
Cardiac Tissue
Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.
Smooth Muscle Tissue
Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.
Nervous Tissue
 Nervous tissue consists of two major kinds of
cells
 Neurons and neuroglia
Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.
Nervous Tissue
Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.
Aging and Tissues
 Tissues heal faster and leave less obvious
scars in the young than in the aged
 The extracellular components of tissues,
such as collagen and elastic fibers, change
with age
Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.
End of Chapter 3
Copyright 2014 John Wiley & Sons, Inc.
All rights reserved. Reproduction or translation of this
work beyond that permitted in section 117 of the 1976
United States Copyright Act without express
permission of the copyright owner is unlawful. Request
for further information should be addressed to the
Permission Department, John Wiley & Sons, Inc. The
purchaser may make back-up copies for his/her own
use only and not for distribution or resale. The
Publishers assumes no responsibility for errors,
omissions, or damages caused by the use of these
programs or from the use of the information herein.
Copyright © 2014 John Wiley & Sons, Inc. All rights reserved.

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ch03.ppt