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Cerebral palsy
By
Dr. Krati Omar
Introduction
• The term cerebral palsy was first used in 1843 by the
English orthopedic surgeon William Little
• It was known for many years as
“Little’s disease”
Cerebral Palsy (CP)
• CP describe a group of permanent disorders of the
development of movement and posture, causing
activity limitation, that are attributed to non-
progressive disturbance that occurred in the
developing fetal or infant brain
• The motor disorders of CP are often accompanied by
disturbance of sensation, cognition, perception,
communication, and secondary problem is
musculoskeletal disorders
A report: the definition and classification of cerebral palsy April 2006, Peter Rosenbaum et.al
Cerebral palsy
• Cerebral palsy (CP) is a broad spectrum of motor
disability which is non progressive and is caused by
damaged to brain at or around birth
• It is a disorder which develops due to damage to CNS
• This damage can happen before, during, or
immediately after the birth of child
Cerebral palsy
• Damaged brain is not able to cope up with the
physical demand of growing body and the increasing
demand of the environment surrounding the child
• CP are the most common cause of childhood
disability
Motor disorder of CP
Musculoskeletal problem
Sensation
behavior
seizures
Perception
Cognition
Communi
cation
Incidence
• The prevalence of CP has consistently been reported
to be about 2-2.5 per 1000 live birth (1 in every 400
children) over the last 20 years in the western world
Etiology
Prenatal cause Perinatal cause Postnatal cause
Prenatal cause
• Vascular events such as a middle cerebral artery infract
• Maternal infection during the first and second trimester
1. Rubella
2. Cytomegalovirus
3. Toxoplasmosis
• Metabolic disorders
• Genetic syndromes
• Hypoglycemia
Perinatal cause
• Problems during labor and delivery
a. Obstructed labor
b. Antepartun hemorrhage
c. Cord prolapsed
• Vascular causes: occlusion of the internal carotid and
midcerebral artery during birth can lead to
hemiplegia
• Prematurity: premature babies are more common to
brain damage either due to trauma during delivery
and later on due to immature respiratory and
cardiovascular system
• Develop hypoxia, low blood pressure, low blood
sugar, jaundice and hemorrhage because of liver
immaturity
• Low birth weight (<2500gm.)
• Trauma:
a. Disproportion
b. Breech delivery
c. Forceps delivery
d. Distortion of head
e. Tearing of tentorium
• Asphyxia: it can occur by accidents and burns, Multiple
deliveries can cause asphyxia of the second or third
infant
Types of Pelvis
Postnatal cause
• Delayed cry: cause asphyxia to the brain causing CP
• Severe jaundice: Presence of high levels of bilirubin
cause basal ganglia damage leading to athetoid
cerebral palsy and high tone deafness
• Infections: meningitis, malaria and septicemia
Risk factors before pregnancy
• Maternal factors:
a. Delayed onset of menstruation
b. Irregular menstruation
c. Long intermenstrual intervals
d. Long intervals between pregnancies
e. Relationship with previous fetal death
• Medical conditions:
a. Intellectual disabilities
b. Seizures
Risk factor during pregnancy
• Multiple pregnancies associated with:
- Preterm delivery
- Poor intrauterine growth
- Intrapartum complication
Risk factor during labor
Cause of Perinatal Asphyxia
 Prolapsed cord
 Massive intrapartum hemorrhage
 Prolonged or traumatic delivery due to cephalopelvic
or abnormal presentation
 Large baby with shoulder dystocia
Event associated with causal factors
 Prolonged second-stage labor
 Premature separation of placenta
 Abnormal fetal position
In preterm can include:
 Meconium-stained fluid
 Tight nuchal cord
Symptoms of CP
Abnormal
strength
Associated
handicapPosture
and
balance
Persistent
motor delay
Abnormal
reflexes
Abnormal
tone
Loss of
control
Cognitive
deficit
Diagnosis
• Cranial ultrasound : High risk preterm infants
• Computed tomography (CT)
• Magnetic resonance imaging (MRI): Brain tissue and
structures
Classification
Topographical
classification
According to
type
Diaplegia
Hemiplegia
Quadriplegia
Spastic
Athetoid
Ataxic
mixed
Diaplegia
Hypoxia
A white
matter infarct in
the periventricular
areas
Spastic
Diaplegia
Diaplegia
• Involvement of four limbs with leg more affected
than hands
• Disturbance in gait
• Balance problem
• Coordination
Anterior
pelvic tilt
Bilateral hip
internal
rotation
Bilateral knee
flexion
Equinovalgus
foot position
Hemiplegia
• It is a subtype of spastic CP
• Involvement of one side of body (upper and lower limb)
• Periventricular white matter abnormalities cause
hemiplegic CP
• Upper extremity is more affected then lower extremity
• More distal involvement then proximal involvement
Hemiplegia
• Muscle spasticity on the affected side decreases
muscle and bone growth
• Decrease range of motion (ROM)
• contractures and limb-length discrepancies on the
involved side
Posture of children with hemiplegic CP
• Shoulder protraction
• Elbow flexion
• Wrist flexion and ulnar deviation
• Pelvic retraction
• Hip internal rotation and flexion
• Knee flexion and
• Forefoot contact only due to plantar flexed foot
Quadriplegia
• Involvement of four limbs
• In this arms are more affected than leg
• It is also called double Hemiplegia
• Extensive lesions affecting the basal ganglia or
occipital area often lead to visual impairments and
seizures
Spastic CP
• Spasticity occurs in approximately 75% of all children
with CP
• “Hypertonia in which resistance to passive
movement increases with increasing velocity of
movement.”
Spastic CP
Athetoid CP
• Athetoid cerebral palsy children exhibits slow,
purposeless, involuntary movements which flow into
each other.
• It occurs due to basal ganglia damage commonly
seen in children who suffers from an attack of
jaundice following birth.
• They may follow abnormal pattern
• The tone in these children generally fluctuates
Athetoid CP
Ataxic CP
• Ataxic CP is primarily a disorder of balance and
control in the timing of coordinated movements
along with weakness, incoordination a wide-based
gait, and tremor
• This type of CP results from deficits in the cerebellum
Ataxic CP
Hypotonic CP
Gross motor function classification system
(GMFCS)
• GMFCS created by Palisano and colleagues in 1997
• It is a classification system based on gross motor
function of children with CP 12 to 18 year
• The GMFCS was develop to measure the “severity of
movement disability” in children with CP
• There are five levels in the test
GMFCS levels
• Level I Walks at home, school, outdoors, and in the
community
• Climbs stairs without using a railing
• Performs gross motor skills such as running and jumping
with limitations of speed, balance, and coordination
• Level II Walks in most settings; difficulties in walking
when carrying objects
• Uses physical assistance, hand‐held walking devices
when there are difficulties with long distances, inclines,
climbs stairs using a railing.
• Level III Walks with hand‐held mobility devices in most
indoor settings; limitations in walking outdoors.
• Climbs stairs using a railing with supervision or
• assistance. Use of wheeled mobility over long distances
and depending on arm function may self‐propel a manual
wheelchair for sports
• Level IV Walks short distances with physical assistance or
uses powered mobility.
• At school and in the community children are transported
in a manual wheelchair or use power mobility.
• Level V Transported in a manual wheelchair in all
settings. Some achieve self‐mobility using powered
mobility with extensive adaptation of seating.
Children have limited control of head, trunk, arms,
and legs.
References
• Pediatric physical therapy, Jan S. Tecklin, fifth edition page no.
187-194
• Physiotherapy in Neuro-conditions, Glady Samuel Raj page no.
233-249
• Treatment of cerebral palsy and motor delay, Sophie Levitt ,
Ann Addition, 6th edition page no. 1-24
• Physical therapy for children, Robert J. Palisano et al, fifth
edition, page 450
• Neurologic Intervention for Physical Therapist Assistants,
Martin Kessler, page 362-370
Thank you

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Cerebral palsy

  • 2. Introduction • The term cerebral palsy was first used in 1843 by the English orthopedic surgeon William Little • It was known for many years as “Little’s disease”
  • 3. Cerebral Palsy (CP) • CP describe a group of permanent disorders of the development of movement and posture, causing activity limitation, that are attributed to non- progressive disturbance that occurred in the developing fetal or infant brain • The motor disorders of CP are often accompanied by disturbance of sensation, cognition, perception, communication, and secondary problem is musculoskeletal disorders A report: the definition and classification of cerebral palsy April 2006, Peter Rosenbaum et.al
  • 4. Cerebral palsy • Cerebral palsy (CP) is a broad spectrum of motor disability which is non progressive and is caused by damaged to brain at or around birth • It is a disorder which develops due to damage to CNS • This damage can happen before, during, or immediately after the birth of child
  • 5. Cerebral palsy • Damaged brain is not able to cope up with the physical demand of growing body and the increasing demand of the environment surrounding the child • CP are the most common cause of childhood disability
  • 6.
  • 7. Motor disorder of CP Musculoskeletal problem Sensation behavior seizures Perception Cognition Communi cation
  • 8. Incidence • The prevalence of CP has consistently been reported to be about 2-2.5 per 1000 live birth (1 in every 400 children) over the last 20 years in the western world
  • 9. Etiology Prenatal cause Perinatal cause Postnatal cause
  • 10. Prenatal cause • Vascular events such as a middle cerebral artery infract • Maternal infection during the first and second trimester 1. Rubella 2. Cytomegalovirus 3. Toxoplasmosis • Metabolic disorders • Genetic syndromes • Hypoglycemia
  • 11. Perinatal cause • Problems during labor and delivery a. Obstructed labor b. Antepartun hemorrhage c. Cord prolapsed • Vascular causes: occlusion of the internal carotid and midcerebral artery during birth can lead to hemiplegia
  • 12. • Prematurity: premature babies are more common to brain damage either due to trauma during delivery and later on due to immature respiratory and cardiovascular system • Develop hypoxia, low blood pressure, low blood sugar, jaundice and hemorrhage because of liver immaturity • Low birth weight (<2500gm.)
  • 13. • Trauma: a. Disproportion b. Breech delivery c. Forceps delivery d. Distortion of head e. Tearing of tentorium • Asphyxia: it can occur by accidents and burns, Multiple deliveries can cause asphyxia of the second or third infant
  • 15. Postnatal cause • Delayed cry: cause asphyxia to the brain causing CP • Severe jaundice: Presence of high levels of bilirubin cause basal ganglia damage leading to athetoid cerebral palsy and high tone deafness • Infections: meningitis, malaria and septicemia
  • 16. Risk factors before pregnancy • Maternal factors: a. Delayed onset of menstruation b. Irregular menstruation c. Long intermenstrual intervals d. Long intervals between pregnancies e. Relationship with previous fetal death
  • 17. • Medical conditions: a. Intellectual disabilities b. Seizures
  • 18. Risk factor during pregnancy • Multiple pregnancies associated with: - Preterm delivery - Poor intrauterine growth - Intrapartum complication
  • 19. Risk factor during labor Cause of Perinatal Asphyxia  Prolapsed cord  Massive intrapartum hemorrhage  Prolonged or traumatic delivery due to cephalopelvic or abnormal presentation  Large baby with shoulder dystocia
  • 20. Event associated with causal factors  Prolonged second-stage labor  Premature separation of placenta  Abnormal fetal position In preterm can include:  Meconium-stained fluid  Tight nuchal cord
  • 21. Symptoms of CP Abnormal strength Associated handicapPosture and balance Persistent motor delay Abnormal reflexes Abnormal tone Loss of control Cognitive deficit
  • 22. Diagnosis • Cranial ultrasound : High risk preterm infants • Computed tomography (CT) • Magnetic resonance imaging (MRI): Brain tissue and structures
  • 24.
  • 25. Diaplegia Hypoxia A white matter infarct in the periventricular areas Spastic Diaplegia
  • 26. Diaplegia • Involvement of four limbs with leg more affected than hands • Disturbance in gait • Balance problem • Coordination
  • 27. Anterior pelvic tilt Bilateral hip internal rotation Bilateral knee flexion Equinovalgus foot position
  • 28. Hemiplegia • It is a subtype of spastic CP • Involvement of one side of body (upper and lower limb) • Periventricular white matter abnormalities cause hemiplegic CP • Upper extremity is more affected then lower extremity • More distal involvement then proximal involvement
  • 29. Hemiplegia • Muscle spasticity on the affected side decreases muscle and bone growth • Decrease range of motion (ROM) • contractures and limb-length discrepancies on the involved side
  • 30. Posture of children with hemiplegic CP • Shoulder protraction • Elbow flexion • Wrist flexion and ulnar deviation • Pelvic retraction • Hip internal rotation and flexion • Knee flexion and • Forefoot contact only due to plantar flexed foot
  • 31.
  • 32. Quadriplegia • Involvement of four limbs • In this arms are more affected than leg • It is also called double Hemiplegia • Extensive lesions affecting the basal ganglia or occipital area often lead to visual impairments and seizures
  • 33.
  • 34.
  • 35. Spastic CP • Spasticity occurs in approximately 75% of all children with CP • “Hypertonia in which resistance to passive movement increases with increasing velocity of movement.”
  • 37. Athetoid CP • Athetoid cerebral palsy children exhibits slow, purposeless, involuntary movements which flow into each other. • It occurs due to basal ganglia damage commonly seen in children who suffers from an attack of jaundice following birth. • They may follow abnormal pattern • The tone in these children generally fluctuates
  • 39. Ataxic CP • Ataxic CP is primarily a disorder of balance and control in the timing of coordinated movements along with weakness, incoordination a wide-based gait, and tremor • This type of CP results from deficits in the cerebellum
  • 42. Gross motor function classification system (GMFCS) • GMFCS created by Palisano and colleagues in 1997 • It is a classification system based on gross motor function of children with CP 12 to 18 year • The GMFCS was develop to measure the “severity of movement disability” in children with CP • There are five levels in the test
  • 44. • Level I Walks at home, school, outdoors, and in the community • Climbs stairs without using a railing • Performs gross motor skills such as running and jumping with limitations of speed, balance, and coordination • Level II Walks in most settings; difficulties in walking when carrying objects • Uses physical assistance, hand‐held walking devices when there are difficulties with long distances, inclines, climbs stairs using a railing.
  • 45. • Level III Walks with hand‐held mobility devices in most indoor settings; limitations in walking outdoors. • Climbs stairs using a railing with supervision or • assistance. Use of wheeled mobility over long distances and depending on arm function may self‐propel a manual wheelchair for sports • Level IV Walks short distances with physical assistance or uses powered mobility. • At school and in the community children are transported in a manual wheelchair or use power mobility.
  • 46. • Level V Transported in a manual wheelchair in all settings. Some achieve self‐mobility using powered mobility with extensive adaptation of seating. Children have limited control of head, trunk, arms, and legs.
  • 47. References • Pediatric physical therapy, Jan S. Tecklin, fifth edition page no. 187-194 • Physiotherapy in Neuro-conditions, Glady Samuel Raj page no. 233-249 • Treatment of cerebral palsy and motor delay, Sophie Levitt , Ann Addition, 6th edition page no. 1-24 • Physical therapy for children, Robert J. Palisano et al, fifth edition, page 450 • Neurologic Intervention for Physical Therapist Assistants, Martin Kessler, page 362-370