Cancer, obesity and nutrition - Roel Tolentino

Cancer, Obesity andCancer, Obesity and
NutritionNutrition
Roel S. Tolentino, MD, MBA,Roel S. Tolentino, MD, MBA, FPCS, FACS, FPSGS, FPSO, FMOSPFPCS, FACS, FPSGS, FPSO, FMOSP
General Surgery – Surgical Oncology
Wellness Coach

Prof. Roel Tolentino, MD, MBA
De La Salle University –De La Salle University – BS. Biology;BS. Biology;
MedicineMedicine
Manila Med –Manila Med – General SurgeryGeneral Surgery
SLMC –SLMC – Surgical OncologySurgical Oncology
Ateneo GSB -Ateneo GSB - MBAMBA
Memorial Sloan Kettering Cancer Center (NYC)
University Hospitals of Columbia University and Cornell Medical College (NYC)
MD Anderson Cancer (Texas)
Beijing Cancer Hospital (China)
Chongqing Medical University (China)
Suining Central Hospital (China)

Oxidative Stress
Free Radicals
Inflammation
Antioxidants
Degenerative Diseases

Ingredients of a Healthy Lifestyle
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Degenerative disease
• a disease in which the function or structure
of the affected tissues or organs will
increasingly deteriorate over
time
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Degenerative disease
11/24/16 10

Metabolism
• all chemical reactions involved in
maintaining the living state of the
cells and the organism.
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Oxidative stress
• imbalance between the production
of free radicals and
neutralization by antioxidants.
11/24/16 21
BAD
GOOD

• Inflammation is a vital part of the body's
immune response.
• It is the body's attempt to heal itself after an
injury.
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Inflammation
- overactive immune system results in the
body being flooded with defense cells and
hormones that damage tissues.
11/24/16 25

Foods That Promote Inflammation
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Antioxidants
• Water Soluble – Vit C and B (for blood)
• Fat Soluble – Vit. E and A (covering of cell)
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a) Phase I – Decreasing the Risk
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b) Phase II – Maximize Antioxidants
and the Immune System
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c) Phase III – Empowering the
Repair System
11/24/16 39

Leukoplakia
Prevention to cancer
progression:
-Vit. A
-Beta carotene
-Vit. C
-Vit. E
11/24/16 43

Antioxidants kill cancer cells
11/24/16 44

Antioxidants protect normal cells
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Cholesterol bad to your health?

• accumulation of calcium and fatty materials
(cholesterol and triglyceride).
11/24/16 51

• Vitamin E
• Vitamin C
• Glutathione
• Phytonutrients
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201611 inches off my waistline11 inches off my waistline
45 lbs off my previous weight45 lbs off my previous weight

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glucosamineglucosamine
Omega 3Omega 3

Osteoarthritis - Treatment
Glucosamine - maintains health of cartilage

Vit. E
(Carbohydrate blocker, Chromium tablet)
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Diabetes

Low Carb and Increased Protein Diet
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Diabetes

• Epigallocatechin gallate (EGCG)Epigallocatechin gallate (EGCG)
• antioxidant
• promotes weight loss by promoting diet-diet-
inducedinduced thermogenesisthermogenesis and fat oxidationfat oxidation

• ChromiumChromium
• aid to controlling blood sugar in people with diabetes or
prediabetes
• may lower cholesterol
• used as weight-loss supplement

• Kidney Bean ExtractKidney Bean Extract
• inhibits amylase
• reduces absorption of starch
• reduction in body fat

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Cancer, obesity and nutrition - Roel Tolentino

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