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NUTRITION AND CANCER
Obesity
 Adult Obesity Rate by State 1990
Obesity
 Adult Obesity Rate by State, 2014
BMI Scale
 A weight that is greater than what is
considered healthy for a given height
 BMI scale BMI
Overweight 25-29.9
Obese >30-34.9
Obese, severe 35-39.9
Obese, morbidity >40
Cancers Associated with Obesity
Breast Colon Rectum
Stomach Esophagus Kidney
Thyroid Pancreas Prostate
Gallbladder
So What’s the Relationship?
 Fat tissue produces excess estrogen
 Higher insulin levels/insulin-like growth factor-1
 Fat cells produce adiposkines
 Chronic low level inflammation
 Maybe related to food types
3 Phases of Nutrition
Prevention
Treatment
Survivorship
Treatment Goals
 Prevent or resolve nutrition deficiencies
 Weight maintenance
 Preserve lean body mass
 Minimize nutrition-related side effects
 Maximize quality of life
Care Team
Rock Star RD
Nutrition Impact Systems
Fatigue Constipation Anorexia
Xerostomia Nausea Emesis
Gas/bloating Reflux SOB
Diarrhea Early Satiety Smell bother
TasteAlteration Mucositis Dysphagia
Weight Loss Weakness
Common Nutrition Questions
Can I drink alcohol during treatment?
1. RDs will discourage and defer
2. Alcohol may impair drug breakdown
3. Increase side effects
4. Sore mouth
Supplements & Vitamins
 Typically discouraged unless ordered
 Defer to Oncologist
 Encouraged whole foods with color
Does Sugar Feed Cancer?
 Recommendation is to avoid added sugars
 Avoid spikes in insulin levels
 Excess insulin = cell growth
Soy & Flaxseed
 If soy was a staple in your diet-continue to eat it-
if not, don’t start per the AICR
 A few servings per week as part of a plant based
diet
 Flaxseed: 2 small studies favorable for breast and
prostate cancer.
 Flaxseed is a great “FLAXative”
Red Meat
 Many organizations support a reduction or
avoidance of red and processed meats
 Links: Colorectal, Prostate, Stomach, Breast,
Ovarian and Lung
 High temp cooking / grilling higher fat meats
and the production of amines
 Heme iron may produce compounds damage
cells
 Nitrites
 Sugar Neu5Gc
World Cancer Research Fund and
AICR
‘The association between consumption of red and
processed meats and cancer, particularly
colorectal cancer is very consistent’
‘red or processed meats are convincing or
probable source s of some cancers’
Survivorship and Nutrition
AICR Recommendations for Cancer Prevention
1. Become lean but not underweight
2. Physical activity 30 mins/day every day
3. Avoid simple sugars
4. Eat more vegs, fruits, whole grains, beans
5. Limit red and processed meats
6. Limit alcohol (2) men and (1) women
7. Limit salty and processed foods
8. Do not take supplements to prevent cancer
9. No smoking
Moving to the Next Level
Lifestyle changes
Weight Management
Nutrition
Activity
Making Changes
Creating Change
AICR Prevention
 Diet with variety of vegetables, fruits, whole
grains, beans, low in red meat/processed meats
 2/3 plate vegetables, fruits, whole grains
 Nobody is perfect nor do we have to be
American Institute for Cancer Research/WorldCancer Fund (2007)
Red Meat
 Link with colorectal cancer
 NIH research
 World Cancer Research Fund and AICR
‘red or processed meats are convincing or
probably sources of some cancers’
 Research is limited but suggestive
• AIRC encouraging meatless meals or to use as
a condiment vs the main event
Alcohol
 AICR recommends to abstain
 Increases circulating estrogen levels
 1 –Women 2- Men
Links
Breast Esophageal Pancreatic
Liver Colon Throat
Mouth Rectum
Salt and Supplements
 Limit consumption of salty foods
 Limit consumption of processed foods
 Do not use supplements to protect against
cancer
Goal for Survivorship
Monitoring/Screenings
Weight Management
Dietary Modifications
Physical Activity
Nutrition and cancer

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Nutrition and cancer

  • 2. Obesity  Adult Obesity Rate by State 1990
  • 3. Obesity  Adult Obesity Rate by State, 2014
  • 4. BMI Scale  A weight that is greater than what is considered healthy for a given height  BMI scale BMI Overweight 25-29.9 Obese >30-34.9 Obese, severe 35-39.9 Obese, morbidity >40
  • 5. Cancers Associated with Obesity Breast Colon Rectum Stomach Esophagus Kidney Thyroid Pancreas Prostate Gallbladder
  • 6. So What’s the Relationship?  Fat tissue produces excess estrogen  Higher insulin levels/insulin-like growth factor-1  Fat cells produce adiposkines  Chronic low level inflammation  Maybe related to food types
  • 7. 3 Phases of Nutrition Prevention Treatment Survivorship
  • 8. Treatment Goals  Prevent or resolve nutrition deficiencies  Weight maintenance  Preserve lean body mass  Minimize nutrition-related side effects  Maximize quality of life
  • 10. Nutrition Impact Systems Fatigue Constipation Anorexia Xerostomia Nausea Emesis Gas/bloating Reflux SOB Diarrhea Early Satiety Smell bother TasteAlteration Mucositis Dysphagia Weight Loss Weakness
  • 11. Common Nutrition Questions Can I drink alcohol during treatment? 1. RDs will discourage and defer 2. Alcohol may impair drug breakdown 3. Increase side effects 4. Sore mouth
  • 12. Supplements & Vitamins  Typically discouraged unless ordered  Defer to Oncologist  Encouraged whole foods with color
  • 13. Does Sugar Feed Cancer?  Recommendation is to avoid added sugars  Avoid spikes in insulin levels  Excess insulin = cell growth
  • 14. Soy & Flaxseed  If soy was a staple in your diet-continue to eat it- if not, don’t start per the AICR  A few servings per week as part of a plant based diet  Flaxseed: 2 small studies favorable for breast and prostate cancer.  Flaxseed is a great “FLAXative”
  • 15. Red Meat  Many organizations support a reduction or avoidance of red and processed meats  Links: Colorectal, Prostate, Stomach, Breast, Ovarian and Lung  High temp cooking / grilling higher fat meats and the production of amines  Heme iron may produce compounds damage cells  Nitrites  Sugar Neu5Gc
  • 16. World Cancer Research Fund and AICR ‘The association between consumption of red and processed meats and cancer, particularly colorectal cancer is very consistent’ ‘red or processed meats are convincing or probable source s of some cancers’
  • 17. Survivorship and Nutrition AICR Recommendations for Cancer Prevention 1. Become lean but not underweight 2. Physical activity 30 mins/day every day 3. Avoid simple sugars 4. Eat more vegs, fruits, whole grains, beans 5. Limit red and processed meats 6. Limit alcohol (2) men and (1) women 7. Limit salty and processed foods 8. Do not take supplements to prevent cancer 9. No smoking
  • 18. Moving to the Next Level Lifestyle changes Weight Management Nutrition Activity
  • 21.
  • 22. AICR Prevention  Diet with variety of vegetables, fruits, whole grains, beans, low in red meat/processed meats  2/3 plate vegetables, fruits, whole grains  Nobody is perfect nor do we have to be American Institute for Cancer Research/WorldCancer Fund (2007)
  • 23. Red Meat  Link with colorectal cancer  NIH research  World Cancer Research Fund and AICR ‘red or processed meats are convincing or probably sources of some cancers’  Research is limited but suggestive • AIRC encouraging meatless meals or to use as a condiment vs the main event
  • 24. Alcohol  AICR recommends to abstain  Increases circulating estrogen levels  1 –Women 2- Men Links Breast Esophageal Pancreatic Liver Colon Throat Mouth Rectum
  • 25. Salt and Supplements  Limit consumption of salty foods  Limit consumption of processed foods  Do not use supplements to protect against cancer
  • 26. Goal for Survivorship Monitoring/Screenings Weight Management Dietary Modifications Physical Activity