Bronchoconstrictor Drugs

1. BRONCHO CONSTRICTORS
PREPARED BY:
USHA RANI KANDULA,
ASSISTANT PROFESSOR,
DEPARTMENT OF ADULT HEALTH NURSING,
ARSI UNIVERSITY,ASELLA,ETHIOPIA,
SOUTH EAST AFRICA.

2. DEFINITION
 The beta 2 receptors, which are
located in the bronchioles of the
lungs, thus reducing bronchodilation
and produce bronchoconstriction
and asthma in susceptible people.
 Bronchoconnstriction is produced as
a side effect of many drugs.

3. -PROPRANOLOL
-NADOLOL
-PINDOLOL
-SOTALOL
-TIMOLOL
The common drugs--

4. PROPRANOLOL

5. PROPRANOLOL
 Propranolol is a non-selective beta
blocker, which blocks the action of
epinephrine on both beta1 and beta
II adrenergic receptors.

6. PROPRANOLOL MOA
 Propranolol is rapidly and completely
absorbeb with peak plasma levels
achieved approximately 1-3 hours
after ingestion.
 It dimnishes cardiac output, having
both negative and chronotropic
effects.

7.  Blocking beta II receptors in the
lungs of susceptible patients causes
contraction of the bronchiolar
smooth muscles.
 This can precipitate a respiratory
crisis in patients with COPD or
asthma.

8. DOSE
 Orally : 10-90 mg
 IV: A concentration of 1mg/ml
 It also available in capsules as
80,120 or 160mg.

9. NADOLOL

10. Nadolol
 Nadolol is a non-selective beta
blocker used in the treatment of high
blood pressure, migraine headache
and chest pain.

11. NADOLOL MOA
 Nadolol is a beta-specific
sympatholytic, which non-selectively
blocks beta I adrenergic receptors,
which located in the heart, inhibiting
the effects of the catecholamines,
epinephrine and norepinephrine and
decrease the heart rate and blood
pressure.

12. DOSE
 Oral (tablets) : 20,40,80,120 and 160 mg

13. SOTALOL

14. Sotalol
 Sotalol is a drug used in individuals
with rhythm disturbances of the
heart and to treat hypertension in
some individuals.

15. TIMOLOL

16.  Timolol maleate is a non-selective
beta-adrenergic receptor blocker.
 It is used to treat high blood
pressure and prevent heart attacks
and prevent migraine headaches.

17. NURSING
RESPONSIBILITIES

18. Nursing responsibilities
 Assess the client for signs of
coronary artery disease and ask the
client to describe his/her anginal
attacks.
 Inquire about the clients use of beta
blockers or other medications to
relieve the pain.

19.  Check the patient pulse rate before
administration of beta blocker may slow
the sinus rate and produce bradycardia.
 Monitor the clients blood pressure for
hypotension.
 Monitor for hypoglycemia.
 Evaluate therapeutic effect of the
medication.

20. PATIENT EDUCATION

21.  Learn to take own pulse and blood
pressure.
 Learn to monitor blood sugar levels.
 Never stop medications.

22. THANKING YOU