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Respiratory Tract Infections Associate Professor Raymond Lin Head, Clinical Microbiology BLT18/2008
 
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[object Object],[object Object],[object Object],[object Object]
Normal oropharyngeal flora ,[object Object],[object Object],[object Object],[object Object],[object Object]
 
Pathogens ,[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object]
Upper respiratory cavity infections ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Eustachian tube in infants – wider & horizontal
 
 
Otitis externa ,[object Object],[object Object],[object Object]
Otitis externa
sinusitis
“ CROUP” laryngo-tracheo-bronchitis hoarse voice, barking cough  severe cases - airway obstruction Laryngitis Parainfluenza viruses
Bronchitis Bronchiolitis Bronchiectasis
Pleural effusion Empyema Pneumothorax
Pneumonia ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Pneumonia - pathogens ,[object Object],[object Object],[object Object],[object Object],[object Object],Viruses more important in children.
Pneumonia ,[object Object],[object Object],[object Object]
Cooling tower - a possible source of  Legionella  infection
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Pneumonia – immunocompromised patients ,[object Object],[object Object],[object Object]
Hospital pathogens
Laboratory approaches ,[object Object],[object Object],[object Object],[object Object],[object Object]
Investigations ,[object Object],[object Object],[object Object],[object Object]
Investigations ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Investigations ,[object Object],[object Object],[object Object],[object Object],[object Object]
 
Sputum specimen composed of  saliva  and  purulent  material
 
 
 
Organisms that can be missed in a sputum BAL -  Legionella -  Pneumocystis jiroveci Respiratory Tract Specimens
 
 
 
 
 
 
Mycobacteria TB bacillus Mycobacterium tuberculosis Non-TB bacilli many species M leprae, M avium, M kansasi etc
TB bacillus Mycobacterium tuberculosis Acid fast bacilli (AFB) when stained with ZN technique Normal habitat infected humans infected cattle Pathogenicity about 10 million people affected 3 million deaths Spread droplets > lungs > lymph / blood > kidney, bone, joints
Mycobacterium tuberculosis ,[object Object],[object Object],[object Object],[object Object]
Tuberculosis - diagnosis ,[object Object],[object Object],[object Object]
Tests for tuberculosis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
Bordetella pertussis (“whooping cough”) ,[object Object],[object Object],[object Object],[object Object]
pertussis ,[object Object],[object Object],[object Object],[object Object],[object Object]
Summary ,[object Object],[object Object],[object Object],[object Object]

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