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Respiratory Tract Infections Professor Mark Pallen Dr Kamran Afzal Classified Microbiologist
Throat/Nasal Swab specimens ,[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Collection of Sputum specimens ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Respiratory tract defences ,[object Object],[object Object],[object Object],[object Object]
Predisposing factors for RTIs ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Upper respiratory tract infections  (URTIs)
1. Cold and Flu ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
2. Influenza ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
3. Sore throat (pharyngitis) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
3. Laryngitis  ,[object Object],[object Object],[object Object],[object Object]
4. Acute epiglottitis ,[object Object],[object Object]
5. Otitis media ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
6. Acute sinusitis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Lower respiratory tract infections  (LRTIs)
1. Acute bronchitis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
2. Bronchiolitis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
3. Lung abscess ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
4. Bronchiectasis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
5.  Pulmonary tuberculosis   ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],Miliary Granuloma Fibrocaseous Mycobacterium
Primary and secondary TB ,[object Object],[object Object],[object Object],[object Object]
6. Pneumonia ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Microbial Pathogens Causing Pneumonia             Pneumocystis carinii S. pneumoniae H. Influenzae M. tuberculosis Enteric aerobic gram-negative bacilli Staph. aureus Pseudomonas aeruginosa Oral anaerobes Streptococcus pneumoniae Haemophilus influenzae Mycoplasma pneumoniae Chlamydia pneumoniae Legionella pneumophila Moraxella catarrhalis Staphylococcus aureus Nocardia  spp. Mycobacterium tuberculosis Chlamydia psittacii Oral anaerobes   Viruses Fungi   Opportunistic Hospital-Acquired Community-Acquired
A. Community-acquired pneumonia ,[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object]
B. Hospital-acquired pneumonia ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Aspiration pneumonia ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
C. Opportunistic pneumonias ,[object Object],[object Object],[object Object],[object Object],[object Object],Pneumocystis carinii Aspergillus Cytomegalovirus
Anatomical Classification LOBAR PNEUMONIA BRONCHOPNEUMONIA INTERSTITIAL
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
A. Lobar Pneumonia ,[object Object],[object Object],[object Object]
Pathology ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object]
B. Bronchopneumonia ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Viral pneumonia ,[object Object],[object Object],[object Object]
C. Atypical Pneumonia ,[object Object],[object Object],[object Object],[object Object]
Comparison Not prominent Prominent  (myalgia, fatigue, N/V, diarrhea) Extra-pulmonary symptoms Purulent Scanty  Sputum Productive cough Dry cough Cough Abrupt Gradual Onset S. pneumoniae ,  H. influenzae ,  K. pneumoniae ,  mixed aerobic and anaerobic oral flora M. pneumoniae ,  L.   pneumophilia,   C. pneumophilla,   viruses, protozoa and fungi Etiology TYPICAL PNEUMONIA ATYPICAL PNEUMONIA
Investigations ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Treatment ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
 
 
 
 
LAW OF CONSERVATION OF KNOWLEDGE ,[object Object],[object Object]

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RTIs

  • 1. Respiratory Tract Infections Professor Mark Pallen Dr Kamran Afzal Classified Microbiologist
  • 2.
  • 3.
  • 4.
  • 5.
  • 6.
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  • 8. Upper respiratory tract infections (URTIs)
  • 9.
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  • 11.
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  • 14.
  • 15.
  • 16. Lower respiratory tract infections (LRTIs)
  • 17.
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  • 19.
  • 20.
  • 21.
  • 22.
  • 23.
  • 24.
  • 25. Microbial Pathogens Causing Pneumonia             Pneumocystis carinii S. pneumoniae H. Influenzae M. tuberculosis Enteric aerobic gram-negative bacilli Staph. aureus Pseudomonas aeruginosa Oral anaerobes Streptococcus pneumoniae Haemophilus influenzae Mycoplasma pneumoniae Chlamydia pneumoniae Legionella pneumophila Moraxella catarrhalis Staphylococcus aureus Nocardia spp. Mycobacterium tuberculosis Chlamydia psittacii Oral anaerobes Viruses Fungi   Opportunistic Hospital-Acquired Community-Acquired
  • 26.
  • 27.
  • 28.
  • 29.
  • 30.
  • 31. Anatomical Classification LOBAR PNEUMONIA BRONCHOPNEUMONIA INTERSTITIAL
  • 32.
  • 33.
  • 34.
  • 35.
  • 36.
  • 37.
  • 38.
  • 39. Comparison Not prominent Prominent (myalgia, fatigue, N/V, diarrhea) Extra-pulmonary symptoms Purulent Scanty Sputum Productive cough Dry cough Cough Abrupt Gradual Onset S. pneumoniae , H. influenzae , K. pneumoniae , mixed aerobic and anaerobic oral flora M. pneumoniae , L. pneumophilia, C. pneumophilla, viruses, protozoa and fungi Etiology TYPICAL PNEUMONIA ATYPICAL PNEUMONIA
  • 40.
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