This document describes various normal and abnormal red blood cell and white blood cell morphologies seen in blood cell examination. It discusses normal red blood cells and then various red blood cell abnormalities including hypochromic, poikilocytes, spherocytes, elliptocytes, target cells, and sickle cells. It also details the normal maturation process of granulocytes from myeloblast to neutrophil and the morphological characteristics of myeloblasts, promyelocytes, myelocytes, metamyelocytes, bands, and segmented neutrophils. Finally, it shows images and descriptions of normal lymphocytes, monocytes, eosinophils, basophils, and platelets.

1. Blood cell morphology
Dr RASHAD S. M. Al-KHWLANY

2. Normal RBCs

3. Reticulocyte

4. Hypochromic RBCs

5. Hypochromic RBCs

6. Poikilocytes

7. Anisocytosis

8. Spherocytes (Microcyte)

9. Spherocytes (Microcyte)

10. Spherocytes (Microcyte)

11. Macrocyte (Megalocytes)

12. Macrocyte (Megalocytes)

13. Elliptocytes (ovalocytes)

14. Elliptocytes (ovalocytes)

15. Target cell

16. Target cell

17. Tear drop cell (Dacryocytes)

18. Tear drop cell (Dacryocytes)

19. Basophilic stippling

20. Polychromatic erythrocytes

21. Howell-Jolly bodies

22. Acanthocytes

23. Acanthocytes

24. Burr cells (crenated cells)

25. Burr cells (crenated cells)

26. Sickle cells (drepanocytes)

27. Sickle cells (drepanocytes)

28. Stomatocytes

29. Stomatocytes

30. Rouleaux

31. Rouleaux

32. Schizocytes (fragmentocytes)

33. Schizocytes (fragmentocytes)

34. Blister Cells

35. Siderocytes

36. Erythrocyte recognizable
maturation

37. WBC Morphology

39. The granulocytic maturation series
Myeloblast Promyelocyte Myelocyte Metamyelocyte Band Neutrophil

40. The maturation sequence
Myeloblast Promyelocyte Myelocyte Metamyelocyte Band Neutrophil

41. Morphological Maturation for Granulocytes

42. Examples: N/C ratio
N/C ratio decreases
as cell matures
Myeoblast
Myelocyte
Metamyelocyte Band Neutrophil

43. Nuclear Shape
The shape of the nucleus may aid in the identification of a cell
From regular round to
irregular in shape as
the cell matures

44. Myeloblast

45. Myeloblast

46. Myeloblast

47. Myeloblast

48. Myeloblast and
Polychromatophilic
normoblasts

49. Myeloblast

50. Myeloblasts, and Lymphocyte

51. Myeloblast, band neutrophil

52. Myeloblasts with few granules,
type 2 and 3

53. Myeloblasts with Auer rods
These rods are only found in myeloblasts and not in
any other blasts, such as lymphoblast or monoblast
on megakaryoblast

55. Auer Rods

56. Promyelocyte

57. Promyelocyte

58. Promyelocyte

59. Promyelocyte or also called
progranulocyte

60. Promyelocyte

61. Myeloblast and Promyelocyte
for comparison
Myeloblast
Promyelocyte

62. Myelocyte

63. Myelocyte

64. Eosino and Neutro myelocytes

65. Eosino and Neutro Myelocyte

66. Band neutrophil,
metamyelocyte, neutrophilic
myelocyte

67. Early Eosino and Neutro
Myelocytes
One Eosinophilic myelocyte (lower left), 1 neutrophilic myelocyte,
1 segmented neutrophil, 1 orthochromic NRBC

68. Neutrophilic Myelocyte

69. Neutrophilic Myelocyte

70. Metamyelocyte

71. Metamyelocyte

72. Neutro Metamyelocyte

73. Eosinophilic Metamyelocyte

74. Bands or Stabs

75. Neutro Band

76. Eosinophilic Band and Neutro Band

77. Eosinophil

78. Basophil

79. Basophil

80. Basophil

81. Basophil

82. Monocyte

83. Plasma cell

84. Atypical Lymphocytes

85. Neutro filaments

87. Red arrow = Band neutrophil, Green arrow = Segmented neutrophil, Yellow arrow =
Myeloblast in transition to promyelocyte, Blue arrow = promyelocyte, Black arrows =
Plasma cells.

88. Eosinophils

89. Seg.Neutro, Lymphocyte and
monocyte

90. Immature Mature

91. Pronormoblast and Myeloblast
‫ا‬ ‫على‬ ‫التعرف‬ ‫في‬ ‫يفيد‬ ‫ان‬ ‫يمكن‬ ‫الستوبالزم‬ ‫لون‬ ‫إذا‬ ،‫المختلفة‬ ‫الخاليا‬ ‫بين‬ ‫الستوبالزم‬ ‫لون‬ ‫يختلف‬ ‫كيف‬ ‫انظر‬
‫المختلفة‬ ‫لخاليا‬
.
‫مختلفة‬ ‫خاليا‬ ‫بين‬ ‫يفرق‬ ‫أو‬ ‫الخلية‬ ‫نفس‬ ‫من‬ ‫المختلفة‬ ‫األطوار‬ ‫بين‬ ‫يفرق‬ ‫أن‬ ‫يمكن‬
.
‫سيت‬ ‫لديها‬ ‫التي‬ ‫الخاليا‬ ‫مثال‬
‫اللون‬ ‫داكن‬ ‫وبالزم‬
‫الصورة‬ ‫هذه‬ ‫في‬ ‫أكثر‬
(
‫ال‬ ‫األسهم‬
‫بيض‬
‫اء‬
)
‫خاليا‬ ‫عليها‬ ‫يطلق‬ ‫والتي‬ ‫متطورة‬ ‫الغير‬ ‫الحمراء‬ ‫للخاليا‬ ‫بصلة‬ ‫تمت‬
‫الـ‬
Pronormoblast
.
‫الـ‬ ‫خلية‬ ‫الى‬ ‫يشير‬ ‫األحمر‬ ‫السهم‬ ‫بينما‬
Myeloblast

92. Promyelocyte and Polychromatophilic normoblast
Promyelocyte with
azurophilic granules that
also cover the nucleus
Neutrophil
Polychromatophilic
normoblast

93. Inclusion bodies: Auer rods
Auer Rods (which are
aggregates of
azurophilic granules)
are found only in
Myeloblasts and
promyelocytes
‫الـ‬ ‫شفت‬ ‫علطول‬ ‫يعنى‬Auer Rods ‫على‬ ‫الخلية‬ ‫تشخص‬
‫انها‬Myeloblast ‫عيونك‬ ‫مغمض‬ ‫وأنت‬
.
‫الحالة‬ ‫وتشخص‬
‫انها‬ ‫على‬Acute Myeloblastic Leukemia
(AML)
Auer rod
Auer Rods. Auer rods are rods or spindle-shaped, cytoplasmic
inclusions. They stain red-purple and are 1 to 6 microns long and
less than 1.5 microns thick. They are frequently found in leukemias.
Auer rod

94. Multiple Auer Rods in Promyelocytes
‫الـ‬
Auer Rods
‫الـ‬ ‫خاليا‬ ‫في‬ ‫توجد‬ ‫وعادة‬ ‫متعددة‬
.Promyelocytes
‫العصي‬ ‫هذي‬ ‫تجد‬ ‫عندما‬
(
Auer Rods
)
‫انها‬ ‫على‬ ‫الحالة‬ ‫تشخص‬
Acute
Myeloblastic Leukemia (AML)
‫انها‬ ‫على‬ ‫تشخص‬ ‫الحالة‬ ‫فان‬ ‫عادة‬ ‫متعددة‬ ‫تجدها‬ ‫عندما‬ ‫ولكن‬
Acute Promyelocytic Leukemia (AML-M3)
‫خلية‬ ‫على‬ ‫ويطلق‬
Promyelocyte
‫بالـ‬ ‫متعددة‬ ‫عصي‬ ‫على‬ ‫تحتوي‬ ‫التي‬
Faggot Cell

95. Normal Blood Cells

96. Neutrophils

97. Band form Neutrophils
• There are smaller
numbers of cells of
neutrophil lineage with
non-segmented nuclei.
They are referred to as
neutrophil band cells or
band forms. They are less
mature than segmented
neutrophils.
• An increased number of
band cells is referred to as
a'left shift'.

98. Eosinophil

99. Basophil

100. Basophils

101. Granulation and type of granules
Basophil
Seg. Neutrophil
Eosinophil

102. Normal lumphocytes

103. Normal monocyte

104. Monocytes

105. Platelet aggregates