Blood is a connective tissue composed of plasma and cellular elements. Plasma, which makes up 55% of blood, contains water, proteins, organic molecules, and inorganic substances. It transports nutrients, gases, hormones, and removes waste. The cellular elements include red blood cells, white blood cells, and platelets. Plasma proteins such as albumin maintain colloidal pressure and blood viscosity while globulins provide immunity. Common conditions affecting plasma protein levels include malnutrition, liver disease, and inflammation.
1) The site (Organs and subcellular localization)
2) Reactions including High quality diagrams showing the reaction with structures.
3) Pathway regulation (Key enzymes and allosteric effectors shown clearly on the pathway with different colors and/or fonts) and hormonal regulation.
Lipoprotein metabolism - (transport of lipids in the Blood)Ashok Katta
This presentation explains metabolism of lipoproteins (Chylomicron, VLDL, LDL, HDL) in very simple way. The presentation contains lots of animation to explain metabolism of individual lipoproteins.
Comprehensive description of various primary dyslipidemias, cholesterol transport and molecular mechanisms involved.
View in slideshow after downloading for better experience.
Prepared in Dec 2013.
Cholesterol (from the Ancient Greek chole- (bile) and stereos (solid), followed by the chemical sufffix -ol for an alcohol) is an organic molecule. It is a sterol (or modified steroid), a type of lipid. Cholesterol is biosynthesized by all animal cells and is an essential structural component of animal cell membranes.
Cholesterol also serves as a precursor for the biosynthesis of steroid hormones, bile acid and vitamin D. Cholesterol is the principal sterol synthesized by all animals. In vertebrates, hepatic cells typically produce the greatest amounts. It is absent among prokaryotes (bacteria and archaea), although there are some exceptions, such as Mycoplasma, which require cholesterol for growth.
cholesterol is essential because it is involved in synthesis of
1. steroidal hormone
2.vitamin-d
3.bile acids
4. it is also structural component of cell membrane
IN PLASMA MEMBRANE
Cholesterol is important in the membrane as it helps to maintain cell membrane stability at varying temperatures. Cholesterol is bound to neighbouring phospholipid molecules via hydrogen bonds and therefore at low temperatures, reduces their packing.
2. TRANSPORTATION
Cholesteryl ester, a dietary lipid, is an ester of cholesterol. The ester bond is formed between the carboxylate group of a fatty acid and the hydroxyl group of cholesterol. Cholesteryl esters have a lower solubility in water due to their increased hydrophobicity. Esters are formed by replacing at least one –OH (hydroxyl) group with an –O–alkyl (alkoxy) group. They are hydrolyzed by pancreatic enzymes, cholesterol esterase, to produce cholesterol and free fatty acids
cholesterol is also important to maintain structure of lipoprotein
Cholesterol travels through the blood on proteins called “lipoproteins.” Two types of lipoproteins carry cholesterol throughout the body:
1.LDL (low-density lipoprotein), sometimes called “bad” cholesterol, makes up most of your body's cholesterol.
2.HDL (high-density lipoprotein) called “good cholesterol” makes a less part of your body’s cholesterol
This powerpoint presentation is about the metabolism of steriods and cholesterol
it gives the pathways and enzymes involved in them
hope this presentation of ours is beneficial to you and informative as well <3
1) The site (Organs and subcellular localization)
2) Reactions including High quality diagrams showing the reaction with structures.
3) Pathway regulation (Key enzymes and allosteric effectors shown clearly on the pathway with different colors and/or fonts) and hormonal regulation.
Lipoprotein metabolism - (transport of lipids in the Blood)Ashok Katta
This presentation explains metabolism of lipoproteins (Chylomicron, VLDL, LDL, HDL) in very simple way. The presentation contains lots of animation to explain metabolism of individual lipoproteins.
Comprehensive description of various primary dyslipidemias, cholesterol transport and molecular mechanisms involved.
View in slideshow after downloading for better experience.
Prepared in Dec 2013.
Cholesterol (from the Ancient Greek chole- (bile) and stereos (solid), followed by the chemical sufffix -ol for an alcohol) is an organic molecule. It is a sterol (or modified steroid), a type of lipid. Cholesterol is biosynthesized by all animal cells and is an essential structural component of animal cell membranes.
Cholesterol also serves as a precursor for the biosynthesis of steroid hormones, bile acid and vitamin D. Cholesterol is the principal sterol synthesized by all animals. In vertebrates, hepatic cells typically produce the greatest amounts. It is absent among prokaryotes (bacteria and archaea), although there are some exceptions, such as Mycoplasma, which require cholesterol for growth.
cholesterol is essential because it is involved in synthesis of
1. steroidal hormone
2.vitamin-d
3.bile acids
4. it is also structural component of cell membrane
IN PLASMA MEMBRANE
Cholesterol is important in the membrane as it helps to maintain cell membrane stability at varying temperatures. Cholesterol is bound to neighbouring phospholipid molecules via hydrogen bonds and therefore at low temperatures, reduces their packing.
2. TRANSPORTATION
Cholesteryl ester, a dietary lipid, is an ester of cholesterol. The ester bond is formed between the carboxylate group of a fatty acid and the hydroxyl group of cholesterol. Cholesteryl esters have a lower solubility in water due to their increased hydrophobicity. Esters are formed by replacing at least one –OH (hydroxyl) group with an –O–alkyl (alkoxy) group. They are hydrolyzed by pancreatic enzymes, cholesterol esterase, to produce cholesterol and free fatty acids
cholesterol is also important to maintain structure of lipoprotein
Cholesterol travels through the blood on proteins called “lipoproteins.” Two types of lipoproteins carry cholesterol throughout the body:
1.LDL (low-density lipoprotein), sometimes called “bad” cholesterol, makes up most of your body's cholesterol.
2.HDL (high-density lipoprotein) called “good cholesterol” makes a less part of your body’s cholesterol
This powerpoint presentation is about the metabolism of steriods and cholesterol
it gives the pathways and enzymes involved in them
hope this presentation of ours is beneficial to you and informative as well <3
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BLOOD composition&functions of blood,plasma proteins.(The Guyton and Hall...Maryam Fida
BLOOD composition&functions of blood,plasma proteins
Blood is a connective tissue in fluid form.
It is considered as the ‘fluid of life’ because it carries oxygen from lungs to all parts of the body and carbon dioxide from all parts of the body to the lungs.
It is known as ‘fluid of growth’ because it carries nutritive substances from the digestive system and hormones from endocrine gland to all the tissues.
The blood is also called the ‘fluid of health’ because it protects the body against the diseases and gets rid of the waste products and unwanted substances by transporting them to the excretory organs like kidneys
function
1. Nutrient Function:
Supplies nutrients like glucose, amino acids, lipids.
2. Respiratory:
carries oxygen to the tissues and transport CO² to lungs for expiration.
3. Excretory:
removes waste products from tissues and carried to the excretory organs like kidneys, skin, liver etc.
4. Regulation of body temperature
5. Defensive function:
WBCs are responsible for this function (Neutophils and monocytes) engulf the bacteria by phagocytosis.
Lymphocytes are involved in immunity.
Eosinophils are responsible for detoxification, disintegration( to break or separate into constituent elements or parts) and removal of foreign proteins.
6. Storage function
Blood cells:
1) Red blood cells or Erythroctes.
2) White blood cells or leukocytes.
3) Platelets or Thrombocytes.
Plasma is the intercellular matrix of the blood
Composition of plasma
Plasma Proteins 7-9%
Albumin
Globulin
Fibrinogen
Dissolved solutes 3%
Water 90%
albumin
Smallest in molecular weight
Synthesized by liver
Provide osmotic pressure. This is needed to maintain volume and pressure of blood
GLOBULIN
Transport and storage proteins
TYPES :
Alpha & beta : transport lipids and fat soluble vitamins (liver)
Gamma globulins : antibodies produced by lymphocytes
(IgD) belong to the group of gamma globulins and serve as defense proteins (antibodies).
IgG is the most abundant immunoglobulin, can cross the placental barrier (maternofetal transmission).
fibrinogen
Imp. clotting factor
Largest molecular weight
Helps in coagulation of blood
All the plasma proteins are synthesized in liver except ?? Gamma globulins (which are derived from B cells)
What is difference between plasma and serum ??
Plasma – fibrinogen = serum
Give the structure and steps of synthesis of Hb.
Give normal values & list functions of Hb.
List physiological & pathological alterations in Hb conc.
describe the fate of Hb.
Give the structure and steps of synthesis of Hb.
Give normal values & list functions of Hb.
List physiological & pathological alterations in Hb conc.
describe the fate of Hb.
dimensions, normal count and functions of RBC.
list of abnormal forms of RBCs
define erythropoiesis, give the different steps.
details of regulation of erythropoiesis =
- erythropoietin
- Vit.B12
- Folic acid
-Factors for Hb
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
2. Define blood, Give its composition and
functions.
Name the plasma proteins, give their
normal values and functions.
3. Blood – is a liquid connective tissue derived from
mesoderm that fills the heart and blood vessels.
physical characteristics
Colour - opaque red due to pigment- haemoglobin.
4. Volume – average adult is 5 -6 L
(8% of body weight)
pH -7.4 ( 7.38 – 7.42) alkaline in nature
Taste - salty
Viscosity – five times >water
5. Specific gravity –
It is the ratio of weight of blood to the weight of
an equal volume of water at 4∘C
Sp. gr. of whole blood - 1.050-1.060 .
Sp.gr. of RBC (1.090) is greater than that of
plasma (1.030)
6. Blood consist of two main parts-
1) Plasma – 55%
2 ) Cellular elements– 45% (PCV or
Haematocrit value)
10. c) Inorganic substances (1% of the solids)
- Na, K, Ca, Mg, Cl, I, Fe, Po4 and Cu.
d) Gases – O2, CO2& N2.
11. 2. Cellular elements – 45%
a) RBC or Erythrocytes (5-6.5 millions / mm3 )
b) WBC or leucocytes (4000-11000/mm3)
c)Platelets or thrombocytes (1.5-4 lac/mm3 )
13. SERUM
- Plasma minus clotting factor ( I, II, V, VIII )
is called Serum.
- Serum contains higher serotonin level (5HT) because
of break down of platelets during clotting.
- Use- 1. biochemical investigations
2. cell culture media
14. Nutritive function –
- It carries glucose, amino acids, fatty acids,
vitamins, electrolytes from gut to tissues.
Respiratory functions –
- It carries O2 from lungs to tissues & carries CO2
from tissues to lungs.
15. • Excretory functions –
- Transport metabolic waste products like
urea, uric acid and creatinine to excretory
organs for disposal.
•Transport function –
- hormones , enzymes & antibodies are
transported to target tissue to modulate
metabolic process .
16. Protective function –
Imp. role in defense
-Phagocytosis- Neutrophils and monocytes
-Immune response -lymphocytes and gamma
globulins
-Detoxification and removal of foreign proteins -
Eosinophils
17. Homeostatic function-
Imp. role in maintaining internal environment of
body.
-water and electrolyte balance of the body.
- Act as buffers- haemoglobin and plasma proteins
18. Maintenance of body temperature –
regulates body temperature.
Reason:-
- specific heat of blood is high
-High heat conductivity of blood
- High latent heat of evaporation of blood
- Body color –
- Provides natural color to the body
- In anaemia and hypovolemia, body becomes pale
19. Maintenance of blood pressure and osmotic
pressure -
Viscosity help in BP maintenance
Fibrinogen and globulins play an Imp. role in blood
viscosity because of asymmetrical shape.
Albumin mainly exerts colloidal osmotic pressure
which help in exchange of fluid at tissue level.
21. Function of plasma protein
1. Maintain colloidal osmotic pressure. (albumin)
2. Maintain viscosity of blood. (fibrinogen & globulin)
3. Maintain acid base balance in body.
4. Helps in coagulation of blood. (fibrinogen & prothrombin)
5. Provides immunity to body. (gamma globulin)
6. Reservoir of protein to body.
7. Transport of Co2, vit A,D,E, thyroxin, cortisol, bile salt, Cu.
8. Provide stability to blood and prevent Rouleaux formation.
(fibrinogen & globulin)
22. 1) Hypoproteinaemia – generalized decrease in
levels of plasma proteins. Leads to severe edema.
- A/E - Dietary deficiency and starvation.
- Malabsorption syndrome like sprue.
- Liver diseases like hepatitis, cirrhosis.
- Renal diseases like nephrotic syndrome.
- Haemorrhage and extensive burns.
- Hereditary and Congenital inborn defect .
23. Hyperproteinaemia – Increase in plasma protein level.
A/E – Acute Inflammatory conditions
- Acute tissue destruction as in myocardial infarction
- Chronic inflammation and malignancies.
- Multiple myeloma – increase Bence Jones proteins.
24. LAQ-
1. Describe the composition & functions of blood.
SAQ-
1. Functions of blood
2. Plasma protein