Ecology is the study of how organisms interact with each other and their environment. Organisms are affected by biotic factors like other living things as well as abiotic factors like temperature, sunlight, and rocks that are non-living. A biome is a large geographic region defined by the plants and animals living there. There are two main types of biomes - terrestrial biomes like tropical forests, tundras, and deserts, as well as aquatic biomes including freshwater ecosystems like lakes and rivers, and marine ecosystems like coral reefs and oceans. Biomes provide habitat for many interconnected species but are threatened by human impacts like climate change and habitat destruction.
This is a presentation about some of the major characteristics of microorganisms (fungi, protists and bacteria)
Acknowledgement to all internet sources of this presentation.
This is a presentation about some of the major characteristics of microorganisms (fungi, protists and bacteria)
Acknowledgement to all internet sources of this presentation.
This presentation is a combination of different slides which I re-purposed. I included a reference of all the slides I used at the end of my presentation.
Environmental segments – Lithosphere: soil formation – components of soils. Hydrosphere: Hydrological cycle , water and river water composition. Fresh water –surface water and ground water.- Biosphere- Atmosphere.- regions of Atmosphere- temperature and composition in different regions – Troposphere, stratosphere, Mesosphere, Thermosphere.
Slide 1: Title Slide
Extrachromosomal Inheritance
Slide 2: Introduction to Extrachromosomal Inheritance
Definition: Extrachromosomal inheritance refers to the transmission of genetic material that is not found within the nucleus.
Key Components: Involves genes located in mitochondria, chloroplasts, and plasmids.
Slide 3: Mitochondrial Inheritance
Mitochondria: Organelles responsible for energy production.
Mitochondrial DNA (mtDNA): Circular DNA molecule found in mitochondria.
Inheritance Pattern: Maternally inherited, meaning it is passed from mothers to all their offspring.
Diseases: Examples include Leber’s hereditary optic neuropathy (LHON) and mitochondrial myopathy.
Slide 4: Chloroplast Inheritance
Chloroplasts: Organelles responsible for photosynthesis in plants.
Chloroplast DNA (cpDNA): Circular DNA molecule found in chloroplasts.
Inheritance Pattern: Often maternally inherited in most plants, but can vary in some species.
Examples: Variegation in plants, where leaf color patterns are determined by chloroplast DNA.
Slide 5: Plasmid Inheritance
Plasmids: Small, circular DNA molecules found in bacteria and some eukaryotes.
Features: Can carry antibiotic resistance genes and can be transferred between cells through processes like conjugation.
Significance: Important in biotechnology for gene cloning and genetic engineering.
Slide 6: Mechanisms of Extrachromosomal Inheritance
Non-Mendelian Patterns: Do not follow Mendel’s laws of inheritance.
Cytoplasmic Segregation: During cell division, organelles like mitochondria and chloroplasts are randomly distributed to daughter cells.
Heteroplasmy: Presence of more than one type of organellar genome within a cell, leading to variation in expression.
Slide 7: Examples of Extrachromosomal Inheritance
Four O’clock Plant (Mirabilis jalapa): Shows variegated leaves due to different cpDNA in leaf cells.
Petite Mutants in Yeast: Result from mutations in mitochondrial DNA affecting respiration.
Slide 8: Importance of Extrachromosomal Inheritance
Evolution: Provides insight into the evolution of eukaryotic cells.
Medicine: Understanding mitochondrial inheritance helps in diagnosing and treating mitochondrial diseases.
Agriculture: Chloroplast inheritance can be used in plant breeding and genetic modification.
Slide 9: Recent Research and Advances
Gene Editing: Techniques like CRISPR-Cas9 are being used to edit mitochondrial and chloroplast DNA.
Therapies: Development of mitochondrial replacement therapy (MRT) for preventing mitochondrial diseases.
Slide 10: Conclusion
Summary: Extrachromosomal inheritance involves the transmission of genetic material outside the nucleus and plays a crucial role in genetics, medicine, and biotechnology.
Future Directions: Continued research and technological advancements hold promise for new treatments and applications.
Slide 11: Questions and Discussion
Invite Audience: Open the floor for any questions or further discussion on the topic.
Professional air quality monitoring systems provide immediate, on-site data for analysis, compliance, and decision-making.
Monitor common gases, weather parameters, particulates.
Introduction:
RNA interference (RNAi) or Post-Transcriptional Gene Silencing (PTGS) is an important biological process for modulating eukaryotic gene expression.
It is highly conserved process of posttranscriptional gene silencing by which double stranded RNA (dsRNA) causes sequence-specific degradation of mRNA sequences.
dsRNA-induced gene silencing (RNAi) is reported in a wide range of eukaryotes ranging from worms, insects, mammals and plants.
This process mediates resistance to both endogenous parasitic and exogenous pathogenic nucleic acids, and regulates the expression of protein-coding genes.
What are small ncRNAs?
micro RNA (miRNA)
short interfering RNA (siRNA)
Properties of small non-coding RNA:
Involved in silencing mRNA transcripts.
Called “small” because they are usually only about 21-24 nucleotides long.
Synthesized by first cutting up longer precursor sequences (like the 61nt one that Lee discovered).
Silence an mRNA by base pairing with some sequence on the mRNA.
Discovery of siRNA?
The first small RNA:
In 1993 Rosalind Lee (Victor Ambros lab) was studying a non- coding gene in C. elegans, lin-4, that was involved in silencing of another gene, lin-14, at the appropriate time in the
development of the worm C. elegans.
Two small transcripts of lin-4 (22nt and 61nt) were found to be complementary to a sequence in the 3' UTR of lin-14.
Because lin-4 encoded no protein, she deduced that it must be these transcripts that are causing the silencing by RNA-RNA interactions.
Types of RNAi ( non coding RNA)
MiRNA
Length (23-25 nt)
Trans acting
Binds with target MRNA in mismatch
Translation inhibition
Si RNA
Length 21 nt.
Cis acting
Bind with target Mrna in perfect complementary sequence
Piwi-RNA
Length ; 25 to 36 nt.
Expressed in Germ Cells
Regulates trnasposomes activity
MECHANISM OF RNAI:
First the double-stranded RNA teams up with a protein complex named Dicer, which cuts the long RNA into short pieces.
Then another protein complex called RISC (RNA-induced silencing complex) discards one of the two RNA strands.
The RISC-docked, single-stranded RNA then pairs with the homologous mRNA and destroys it.
THE RISC COMPLEX:
RISC is large(>500kD) RNA multi- protein Binding complex which triggers MRNA degradation in response to MRNA
Unwinding of double stranded Si RNA by ATP independent Helicase
Active component of RISC is Ago proteins( ENDONUCLEASE) which cleave target MRNA.
DICER: endonuclease (RNase Family III)
Argonaute: Central Component of the RNA-Induced Silencing Complex (RISC)
One strand of the dsRNA produced by Dicer is retained in the RISC complex in association with Argonaute
ARGONAUTE PROTEIN :
1.PAZ(PIWI/Argonaute/ Zwille)- Recognition of target MRNA
2.PIWI (p-element induced wimpy Testis)- breaks Phosphodiester bond of mRNA.)RNAse H activity.
MiRNA:
The Double-stranded RNAs are naturally produced in eukaryotic cells during development, and they have a key role in regulating gene expression .
A brief information about the SCOP protein database used in bioinformatics.
The Structural Classification of Proteins (SCOP) database is a comprehensive and authoritative resource for the structural and evolutionary relationships of proteins. It provides a detailed and curated classification of protein structures, grouping them into families, superfamilies, and folds based on their structural and sequence similarities.
Observation of Io’s Resurfacing via Plume Deposition Using Ground-based Adapt...Sérgio Sacani
Since volcanic activity was first discovered on Io from Voyager images in 1979, changes
on Io’s surface have been monitored from both spacecraft and ground-based telescopes.
Here, we present the highest spatial resolution images of Io ever obtained from a groundbased telescope. These images, acquired by the SHARK-VIS instrument on the Large
Binocular Telescope, show evidence of a major resurfacing event on Io’s trailing hemisphere. When compared to the most recent spacecraft images, the SHARK-VIS images
show that a plume deposit from a powerful eruption at Pillan Patera has covered part
of the long-lived Pele plume deposit. Although this type of resurfacing event may be common on Io, few have been detected due to the rarity of spacecraft visits and the previously low spatial resolution available from Earth-based telescopes. The SHARK-VIS instrument ushers in a new era of high resolution imaging of Io’s surface using adaptive
optics at visible wavelengths.
Cancer cell metabolism: special Reference to Lactate PathwayAADYARAJPANDEY1
Normal Cell Metabolism:
Cellular respiration describes the series of steps that cells use to break down sugar and other chemicals to get the energy we need to function.
Energy is stored in the bonds of glucose and when glucose is broken down, much of that energy is released.
Cell utilize energy in the form of ATP.
The first step of respiration is called glycolysis. In a series of steps, glycolysis breaks glucose into two smaller molecules - a chemical called pyruvate. A small amount of ATP is formed during this process.
Most healthy cells continue the breakdown in a second process, called the Kreb's cycle. The Kreb's cycle allows cells to “burn” the pyruvates made in glycolysis to get more ATP.
The last step in the breakdown of glucose is called oxidative phosphorylation (Ox-Phos).
It takes place in specialized cell structures called mitochondria. This process produces a large amount of ATP. Importantly, cells need oxygen to complete oxidative phosphorylation.
If a cell completes only glycolysis, only 2 molecules of ATP are made per glucose. However, if the cell completes the entire respiration process (glycolysis - Kreb's - oxidative phosphorylation), about 36 molecules of ATP are created, giving it much more energy to use.
IN CANCER CELL:
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
introduction to WARBERG PHENOMENA:
WARBURG EFFECT Usually, cancer cells are highly glycolytic (glucose addiction) and take up more glucose than do normal cells from outside.
Otto Heinrich Warburg (; 8 October 1883 – 1 August 1970) In 1931 was awarded the Nobel Prize in Physiology for his "discovery of the nature and mode of action of the respiratory enzyme.
WARNBURG EFFECT : cancer cells under aerobic (well-oxygenated) conditions to metabolize glucose to lactate (aerobic glycolysis) is known as the Warburg effect. Warburg made the observation that tumor slices consume glucose and secrete lactate at a higher rate than normal tissues.
THE IMPORTANCE OF MARTIAN ATMOSPHERE SAMPLE RETURN.Sérgio Sacani
The return of a sample of near-surface atmosphere from Mars would facilitate answers to several first-order science questions surrounding the formation and evolution of the planet. One of the important aspects of terrestrial planet formation in general is the role that primary atmospheres played in influencing the chemistry and structure of the planets and their antecedents. Studies of the martian atmosphere can be used to investigate the role of a primary atmosphere in its history. Atmosphere samples would also inform our understanding of the near-surface chemistry of the planet, and ultimately the prospects for life. High-precision isotopic analyses of constituent gases are needed to address these questions, requiring that the analyses are made on returned samples rather than in situ.
Earliest Galaxies in the JADES Origins Field: Luminosity Function and Cosmic ...Sérgio Sacani
We characterize the earliest galaxy population in the JADES Origins Field (JOF), the deepest
imaging field observed with JWST. We make use of the ancillary Hubble optical images (5 filters
spanning 0.4−0.9µm) and novel JWST images with 14 filters spanning 0.8−5µm, including 7 mediumband filters, and reaching total exposure times of up to 46 hours per filter. We combine all our data
at > 2.3µm to construct an ultradeep image, reaching as deep as ≈ 31.4 AB mag in the stack and
30.3-31.0 AB mag (5σ, r = 0.1” circular aperture) in individual filters. We measure photometric
redshifts and use robust selection criteria to identify a sample of eight galaxy candidates at redshifts
z = 11.5 − 15. These objects show compact half-light radii of R1/2 ∼ 50 − 200pc, stellar masses of
M⋆ ∼ 107−108M⊙, and star-formation rates of SFR ∼ 0.1−1 M⊙ yr−1
. Our search finds no candidates
at 15 < z < 20, placing upper limits at these redshifts. We develop a forward modeling approach to
infer the properties of the evolving luminosity function without binning in redshift or luminosity that
marginalizes over the photometric redshift uncertainty of our candidate galaxies and incorporates the
impact of non-detections. We find a z = 12 luminosity function in good agreement with prior results,
and that the luminosity function normalization and UV luminosity density decline by a factor of ∼ 2.5
from z = 12 to z = 14. We discuss the possible implications of our results in the context of theoretical
models for evolution of the dark matter halo mass function.
5. BIOTIC FACTORS
• The living factors in the environment.
• “bio” means life
•Biotic factors in a river include: fishes,
phytoplanktons, crabs, and plants near it
6. ABIOTIC FACTORS
• The non-living factors in the environment.
• Abiotic factors in a river include: rocks, sand,
temperature, sunlight, etc…
9. RECITATION
• TELL IF THE FOLLOWING ARE BIOTIC OR ABIOTIC
• PREDATORS
• WATER
• ROCKS
• PARASITES
• TREES
• GRASS
• CLIMATE
• AIR
• RAINFALL
• FROST
• FUNGI
• CARNIVORES
10. WHAT IS A BIOME?
A biome is a specific geographic area notable for the
species living there. A biome can be made up of
many ecosystems.
11. Is biome the same as
ecosystem?
No. Ecosystem is the interaction between living and
non-living things.
13. I. TERRESTRIAL BIOMES
• These biomes contain smaller but related ecosystems
that are distinguished by similar plant and animal life-
forms.
• Eight major terrestrial biomes include: tropical forest,
temperate forest, taiga, tundra, desert, grassland,
savanna, and shrubland.
14. TROPICAL FOREST
• Found near the equator (Asia, Africa, South America,
and Central America)
• Temperature is always warm and varies a little (20 to
34 degrees Celsius)
• Receives abundant rainfall.
• Two types: tropical seasonal forest and tropical
rainforest
17. TAIGA
• Very cold forests
• Found in the Northern hemisphere (across North
America, Europe, and Asia)
• Temperature ranges from -10 to 14 degrees Celsius
20. TEMPERATE FOREST
• Found south of taigas (eastern parts of North America,
eastern parts of Asia, Europe, and some parts in the
Southern Hemisphere)
• Temperature ranges from 6 to 28 degrees Celsius and
changes every season
• Has well-defined seasons: summer, spring, winter,
autumn
23. TUNDRA
• Found in the Arctic circle, south of the Polar ice caps
in the Northern Hemisphere.
• Temperature ranges from -26 to 12 degrees Celsius
• Characterized by a thin layer of topsoil over the
permafrost
• Permafrost is a layer of frozen ground that reaches a
temperature below 0 degree Celsius.
25. DESERT
• Found on every continent except Europe.
• Temperature ranges from 7 to 38 degrees Celsius.
• Plants and animals are adapted to endure dry, hot
conditions.
27. SAVANNA
• Found in South Asia, Australia, South America, and in
Central and Southern Africa.
• Temperature ranges from 16 to 24 degrees Celsius
• Characterized as tropical grasslands with scattered
deciduous trees and shrubs
• A deciduous plant loses its leaves in autumn and grows
new ones in the spring.
29. GRASSLAND
• Found in Asia, North America, South America,
Australia, and Africa.
• Temperature ranges from 0 to 25 degrees Celsius.
• Covered with tall grasses in moist areas and short
grasses in drier areas.
32. SHRUBLAND
• Also called as chaparrals
• Found surrounding the Mediterranean Sea, Western
coasts of North and South America, South Africa, and
Australia.
• Temperature ranges from 1- to 40 degrees Celsius.
• Region is dominated by either small trees or shrubs.
• Leaves of the plants in shrublands are called
evergreen.
35. II. AQUATIC BIOMES
•Water covers almost three-fourths of the Earth’s
surface and is also a home to aquatic organisms.
•Aquatic biomes are classified into two types:
freshwater and marine biomes
•These biomes differ in salinity (dissolved salt
level – NaCl, Mg, Calcium sulfates, and
bicarbonates)
40. STREAMS
• a body of water with surface water flowing within the bed and banks
of a channel
41. WETLANDS
• a distinct ecosystem that is flooded by water, either permanently or
seasonally, where oxygen-free processes prevail.
42. MARINE BIOMES
•Primarily made up of the saltwater oceans.
•Estuaries are areas where freshwater from rivers
meet and mix with marine water, creating
brackish water.
•Brackish - saltier than fresh water, but not as salty
as seawater.
47. ACTIVITY
• ESSAY: Answer this in your notebook.
• Impacts of biome destruction follow: Increased
flooding due to the erosion of soil and lack of trees.
Rising of the sea levels due to the melting of the
glaciers, caused by Global Warming. Disruption of the
food chain when the apex predators become extinct.
With these effects, can you explain that man is
responsible in everything he does?
Editor's Notes
Evergreen – leaves stay in branches all throughout the year.
A mangrove is a shrub or small tree that grows in coastal saline or brackish water.