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Biosynthetic_Pathways
The document discusses biosynthetic pathways of secondary metabolites and the biogenesis of various pharmaceutically important compounds. It outlines the main metabolic pathways, including the acetate mevalonate and shikimic acid pathways, detailing the biosynthesis of compounds like menthol, vitamin A, and various alkaloids. Additionally, it highlights the precursors for carbohydrates, steroids, fatty acids, aromatic amino acids, and flavonoids.
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Biosynthetic_Pathways
- 1. Biosynthetic Studies And BasicMetabolic Pathways DR. SIDDHI UPADHYAY H.O.D. & ASSOCIATE PROFESSOR Dept. of Pharmacognosy and Phytochemistry SIGMA INSTITUTE OF PHARMACY
- 2. CONTENT •Brief introduction tobiosynthetic pathways of secondary metabolite. Biogenesis of pharmaceutically important compounds •Acetate mevalonate: Menthol, Vitamin-A, Diosgenin, β-amyrin, Glycyrrhetinic acid, Carotenoids •Shikimic acid: Atropine, Quinine, Reserpine, Morphine, Podophyllotoxin, Ephedrine, Colchicine, Ergot Alkaloids •Acetate malonate: Linoleic acid, Omega-3 fatty acid
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- 4. BASIC BIOSYNTHETIC PATHWAYS 1.Calvin cycle - precursor for carbohydrates 2. Acetate Mevalonate Pathway - precursor for steroids, terpenoids 3. Acetate Malonate Pathway - precursor for fatty acids 4. Polyacetate Malonate Pathway - precursor for anthraquinones 5. Shikimic Acid Pathway - precursor for aromatic amino acids 6. Amino Acid Pathway - precursor for aliphatic amino acids 7. Flavonoid Pathway - precursor for flavonoids
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- 18. Biosynthesis of Omega-3fatty acids They are PUFA (polyunsaturated fatty acids) named EPA (Eicosapentaenoic Acid), DHA (Docosahexaenoic Acid)
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- 27. Biosynthesis of ErgotAlkaloids
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