Biomechanics is the study of biological systems using mechanical principles. It draws from biology and physics to describe the movement of living organisms. Biomechanics aids in understanding human movement through analyzing kinetics, which examines causes of motion like forces and torques, and kinematics, which describes motion in terms of displacement, velocity and acceleration. Proper biomechanical analysis is important for understanding injuries and designing rehabilitation.
Introduction to kinesiology (Biomechanics- Physiotherapy) vandana7381
Chapter 1: Introduction to Kinesiology ( Biomechanics) for physical therapy students.
Reference: JOINT STRUCTURE AND FUNCTION - by Pamela K. Levangie.
Easy to understand and with lot of examples.
Introduction to kinesiology (Biomechanics- Physiotherapy) vandana7381
Chapter 1: Introduction to Kinesiology ( Biomechanics) for physical therapy students.
Reference: JOINT STRUCTURE AND FUNCTION - by Pamela K. Levangie.
Easy to understand and with lot of examples.
Biomechanics of Tendon, Ligament, Cartilage,, Bone
Wolf's Law
Mechnical Behavior
stress strain curve (Young's Moudulas)
viscoelasticity
time depended and rate depended properties
creep stress relaxation, hyteresis,
Thank You
Goniometry is the measuring of angles created by the bones of the body at the joints.1, 2, 3
The term goniometry is derived from two Greek words, gonia meaning angle and metron, meaning measure. 1, 2, 3, 4, 5,
System to measure the joint ranges in each plane of the joint is termed goniometry. 4
These measurements are done with instrument such as goniometer, a tape measure, inclinometers or by visual estimate.
Posture - a perquisite for functional abilities in daily life. Posture is a combination of anatomy and physiology with inherent application of bio-mechanics and kinematics. Sitting, standing, walking are all functional activities depending on the ability of the body to support that posture to carry out each activity. Injuries and pathologies either postural or structural can massively change the bio-mechanics of posture and thus affect functional abilities.
Biomechanics of Tendon, Ligament, Cartilage,, Bone
Wolf's Law
Mechnical Behavior
stress strain curve (Young's Moudulas)
viscoelasticity
time depended and rate depended properties
creep stress relaxation, hyteresis,
Thank You
Goniometry is the measuring of angles created by the bones of the body at the joints.1, 2, 3
The term goniometry is derived from two Greek words, gonia meaning angle and metron, meaning measure. 1, 2, 3, 4, 5,
System to measure the joint ranges in each plane of the joint is termed goniometry. 4
These measurements are done with instrument such as goniometer, a tape measure, inclinometers or by visual estimate.
Posture - a perquisite for functional abilities in daily life. Posture is a combination of anatomy and physiology with inherent application of bio-mechanics and kinematics. Sitting, standing, walking are all functional activities depending on the ability of the body to support that posture to carry out each activity. Injuries and pathologies either postural or structural can massively change the bio-mechanics of posture and thus affect functional abilities.
Introduction, Translational Motion, Rotational Motion, Analogous Elements, Electrical Elements, Analogous System, Force - Voltage Analogy, Torque Voltage Analogy, Force - Current Analogy, and Steps to solve problems on analogous systems.
Single degree of freedom system free vibration part -i and iiSachin Patil
Dynamics of Machinery Unit -I ( SPPU Pune) Single Degree of Freedom Free Vibration - Fundamentals of Vibration , Determination of natural Frequency , Problems on Spring in Series and Parallel , Problems on Equilibrium and Energy Method
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Ocular injury ppt Upendra pal optometrist upums saifai etawah
Biomechanics concepts
1. BIOMECHANICS
CONCEPTS
BIOMECHANICS
Study of Biological Systems by
Means of Mechanical Principles
father of Mechanics
Sir Isaac Newton
2. Biology Physics
Skeletal Muscular Nervous Mechanics
system system system
Kinetics Kinematics
22-Jun-12 P.Ratan (MPT, Ortho & Sports) 2
3. HUMAN MOVEMENT ANALYSIS
BIOMECHANICS KINESIOLOGY
KINETICS KINEMATICS FUNCTIONAL
Linear Angular Linear Angular
Position Position
Velocity Velocity Force Torque
Acceleration Acceleration
22-Jun-12 P.Ratan (MPT, Ortho & Sports) 3
4. Basic types of Motion
Linear
Rectilinear
Curvilinear
Angular or rotational
Combined or general
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5. Human Analysis
Internal: mechanical factors
creating and controlling
movement inside the body
External: factors affecting
motion from outside the body
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6. Kinematics
Describes motion
Time
Position
Displacement
Velocity
Acceleration
Vectors
Angular and linear quantities
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8. Kinetics
Explains causes of motion Axis
Mass
amount of matter (kg)
Inertia: resistance to being moved
Moment of Inertia (rotation) I = m·r2
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9. Kinetics
Force: push or pull that tends to
produce acceleration
Important factor in injuries
Vector
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10. Kinetics
Idealized force vector
Force couple system
F
F’ F M=Fd
d d d
= =
F F
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11. Kinetics: Force
Force & Injury factors
Magnitude
Location
Direction
Duration
Frequency
Variability
Rate
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12. Kinetics: Force System
Linear
Parallel
Concurrent
General
Force Couple
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13. Center of Mass (COm) or
Gravity (COG)
It is an imaginary point where
there is intersection of all 3
cardinal plane.
Imaginary point where all the
mass of the body or system is
concentrated
Point where the body’s mass is
equally distributed
22-Jun-12 P.Ratan (MPT, Ortho & Sports) 13
14. Pressure
P = F/A
Units (Pa = N m2)
In the human body also
called stress
Important predisposing
factor for injuries
22-Jun-12 P.Ratan (MPT, Ortho & Sports) 14
15. Moments of Force
(Torque)
Effect of a force that tends
to cause rotation about an
axis
M = F ·d (Nm)
If F and d are
Force through axis
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16. Moments of Force
(Torque)
Force components
Rotation
Stabilizing or destabilizing
component
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17. Moments of Force
(Torque)
Net Joint Moment
Sum of the moments acting
about an axis
Human: represent the
muscular activity at a joint
Concentric action
Eccentric action
Isometric
22-Jun-12 P.Ratan (MPT, Ortho & Sports) 17
18. Moments of Force
(Torque)
Large moments tends to produce injuries on the
musculo-skeletal system
Structural deviation leads to different MA’s
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20. 1st Law of Motion
A body a rest or in a
uniform (linear or angular)
motion will tend to remain
at rest or in motion unless
acted by an external force
or torque
Whiplash injuries
22-Jun-12 P.Ratan (MPT, Ortho & Sports) 20
21. 2nd Law of Motion
A force or torque acting on a body will produce an
acceleration proportional to the force or torque
F = m ·a or T= I ·
F
22-Jun-12 P.Ratan (MPT, Ortho & Sports) 21
22. 3rd Law of Motion
For every action there is an
equal and opposite reaction
(torque and/or force)
Contact forces: GRF, other
players etc.
GRF
22-Jun-12 P.Ratan (MPT, Ortho & Sports) 22
23. Equilibrium
Sum of forces and the sum of
moments must equal zero
F=0
M=0
Dynamic Equilibrium
Must follow equations of motions
F=mxa
T=Ix
22-Jun-12 P.Ratan (MPT, Ortho & Sports) 23
24. Work & Power
Mechanical Work
W= F ·d (Joules)
W= F ·d·cos ( )
Power: rate of work
d
P = W/ t (Watts)
W W
P = F ·v
P = F ·(d/t)
22-Jun-12 P.Ratan (MPT, Ortho & Sports) 24
25. Mechanical Energy
Capacity or ability to
do work
Accounts for most
severe injuries
Classified into
Kinetic (motion)
Potential (position or
deformation)
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26. Kinetic Energy
Body’s motion
Linear or Angular
KE=.5·m·v2
KE =.5 ·I· 2
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27. Potential Energy
Gravitational: potential to
perform work due to the
height of the body
Ep= m·g·h
Strain: energy stored due to
deformation
Es= .5·k·x2
22-Jun-12 P.Ratan (MPT, Ortho & Sports) 27
28. Total Mechanical Energy
Body segment’s: rigid (nodeformable), no strain
energy in the system
TME = Sum of KE, KE , PE
TME = (.5·m ·v2)+(.5 ·I · 2)+(m ·g ·h )
22-Jun-12 P.Ratan (MPT, Ortho & Sports) 28
29. Momentum
P
Quantity of motion
p=m ·v (linear)
Conservation of Momentum
Transfer of Momentum
Injury may result when momentum
transferred exceeds the tolerance
of the tissue
Impulse = Momentum
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30. Angular Momentum
Quantity of angular
motion
H=I · (angular)
Conservation of angular
momentum
Transfer of angular
momentum
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31. Collisions
Large impact forces due to short impact time
Elastic deformation
Plastic deformation (permanent change)
Elasticity: ability to return to original shape
Elastoplastic collisions
Some permanent deformation
Transfer and loss of energy & velocity
Coefficient of restitution
e=Rvpost/Rvpre
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32. Friction
Resistance between two bodies
trying to slide
Imperfection of the surfaces
Microscopic irregularities -
asperities
Static friction
f< s·N
f
Kinetic
f=µk·N N
22-Jun-12 P.Ratan (MPT, Ortho & Sports) 32
