Biodiversity depletion refers to the reduction or loss of plant and animal species. It can occur due to natural causes like floods, earthquakes, and diseases, or anthropogenic causes like urbanization, expansion of agriculture, deforestation, pollution, acidification of soil and water, mining, desertification, and loss of soil fertility. All of these human activities can destroy natural habitats and eliminate important species, contributing to overall biodiversity depletion. Protecting biodiversity will require collective global efforts to reduce human impacts and preserve natural resources for future generations.